Mussel-Inspired Hydrogel Composite with Multi-Stimuli Responsive Behavior
Abstract
A mussel-inspired adhesive hydrogel with pH, temperature, and near-infrared (NIR) light–responsive behavior is designed here. The hydrogel system is formulated by combining chitosan modified with catechol motifs, thermo-responsive poly(N-isopropylacrylamide) terminated with catechols, and light-absorbing polypyrrole nanoparticles (PpyNPs). The effects of catechol concentration, molar ratio of Fe3+ to catechol units, pH, and the incorporation of the PpyNPs on the mechanical property of the formed hydrogel are investigated. The responsive behaviors of the resulting hydrogel composite to pH, temperature, and NIR light are also demonstrated. The obtained hydrogel also shows promising adhesive property to glass and steel substrates. It is anticipated that the fabricated adhesive hydrogel with multi-responsive behavior, especially NIR light response, can potentially be useful in a wide range of biomedical applications, such as remotely controlled release systems and removable sealant materials.
- Authors:
-
[1]
- Case Western Reserve Univ., Cleveland, OH (United States). Dept. of Macromolecular Science and Engineering
- Univ. of California, Berkeley, CA (United States). Dept. of Bioengineering
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Chemical Sciences Division
- Publication Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Case Western Reserve Univ., Cleveland, OH (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22); National Science Foundation (NSF)
- OSTI Identifier:
- 1511921
- Grant/Contract Number:
- AC05-00OR22725; CHE 1608457; CMMI NM 1333651; STC-0423914
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Macromolecular Materials and Engineering
- Additional Journal Information:
- Journal Volume: 304; Journal Issue: 7; Journal ID: ISSN 1438-7492
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING; adhesive properties; catechol-rich polymers; Fe3+–catechol complexation; multi-stimuli responsiveness; near-infrared light responsiveness
Citation Formats
Yan, Yun‐Hui, Rong, Li‐Han, Ge, Jin, Tiu, Brylee David B., Cao, Peng‐Fei, and Advincula, Rigoberto C. Mussel-Inspired Hydrogel Composite with Multi-Stimuli Responsive Behavior. United States: N. p., 2019.
Web. doi:10.1002/mame.201800720.
Yan, Yun‐Hui, Rong, Li‐Han, Ge, Jin, Tiu, Brylee David B., Cao, Peng‐Fei, & Advincula, Rigoberto C. Mussel-Inspired Hydrogel Composite with Multi-Stimuli Responsive Behavior. United States. doi:10.1002/mame.201800720.
Yan, Yun‐Hui, Rong, Li‐Han, Ge, Jin, Tiu, Brylee David B., Cao, Peng‐Fei, and Advincula, Rigoberto C. Tue .
"Mussel-Inspired Hydrogel Composite with Multi-Stimuli Responsive Behavior". United States. doi:10.1002/mame.201800720. https://www.osti.gov/servlets/purl/1511921.
@article{osti_1511921,
title = {Mussel-Inspired Hydrogel Composite with Multi-Stimuli Responsive Behavior},
author = {Yan, Yun‐Hui and Rong, Li‐Han and Ge, Jin and Tiu, Brylee David B. and Cao, Peng‐Fei and Advincula, Rigoberto C.},
abstractNote = {A mussel-inspired adhesive hydrogel with pH, temperature, and near-infrared (NIR) light–responsive behavior is designed here. The hydrogel system is formulated by combining chitosan modified with catechol motifs, thermo-responsive poly(N-isopropylacrylamide) terminated with catechols, and light-absorbing polypyrrole nanoparticles (PpyNPs). The effects of catechol concentration, molar ratio of Fe3+ to catechol units, pH, and the incorporation of the PpyNPs on the mechanical property of the formed hydrogel are investigated. The responsive behaviors of the resulting hydrogel composite to pH, temperature, and NIR light are also demonstrated. The obtained hydrogel also shows promising adhesive property to glass and steel substrates. It is anticipated that the fabricated adhesive hydrogel with multi-responsive behavior, especially NIR light response, can potentially be useful in a wide range of biomedical applications, such as remotely controlled release systems and removable sealant materials.},
doi = {10.1002/mame.201800720},
journal = {Macromolecular Materials and Engineering},
number = 7,
volume = 304,
place = {United States},
year = {2019},
month = {4}
}
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