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Title: Light-Induced Reversible DNA Ligation of Gold Nanoparticle Superlattices

Journal Article · · ACS Nano

DNA-mediated self-assembly of nanoparticles has been of significant interest because it enables access to nanoparticle superstructures that cannot be synthesized otherwise. Yet, the programmability of higher order nanoparticle structures can be easily lost under DNA denaturing conditions. Here, we demonstrate that light can be employed as an external stimulus to master the stability of nanoparticle superlattices (SLs) via the promotion of a reversible photoligation of DNA in SLs. The oligonucleotides attached to the nanoparticles are encoded to ligate using 365 nm light, effectively locking the SLs and rendering them stable under DNA denaturing conditions. The reversible process of unlocking these structures is possible by irradiation with light at 315 nm, recovering the structures to their natural state. Our work inspires an alternative research direction toward postassembly manipulation of nanoparticle superstructures using external stimuli as a tool to enrich the library of additional material forms and their application in different media and environments.

Research Organization:
Univ. of Southampton (United Kingdom); Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22). Materials Sciences & Engineering Division; USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
SC0008772; SC0012704
OSTI ID:
1511760
Alternate ID(s):
OSTI ID: 1518952; OSTI ID: 1562481
Report Number(s):
BNL-212096-2019-JAAM
Journal Information:
ACS Nano, Vol. 13, Issue 5; ISSN 1936-0851
Publisher:
American Chemical Society (ACS)Copyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 25 works
Citation information provided by
Web of Science

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Cited By (2)

DNA‐ and Field‐Mediated Assembly of Magnetic Nanoparticles into High‐Aspect Ratio Crystals journal December 2019
Light‐Responsive Colloidal Crystals Engineered with DNA journal January 2020

Figures / Tables (4)