Absence of Thiol-Disulfide Oxidoreductase DsbA Impairs cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus
Abstract
The thiol-disulfide oxidoreductase DsbA carries out oxidative folding of extra-cytoplasmic proteins by catalyzing the formation of intramolecular disulfide bonds. It has an important role in various cellular functions, including cell division. The purple non-sulfur bacterium Rhodobacter capsulatus mutants lacking DsbA show severe temperature-sensitive and medium-dependent respiratory growth defects. In the presence of oxygen, at normal growth temperature (35°C), DsbA- mutants form colonies on minimal medium, but they do not grow on enriched medium where cells elongate and lyse. At lower temperatures (i.e., 25°C), cells lacking DsbA grow normally in both minimum and enriched media, however, they do not produce the cbb3-type cytochrome c oxidase (cbb3-Cox) on enriched medium. Availability of chemical oxidants (e.g., Cu2+ or a mixture of cysteine and cystine) in the medium becomes critical for growth and cbb3-Cox production in the absence of DsbA. Indeed, addition of Cu2+ to the enriched medium suppresses, and conversely, omission of Cu2+ from the minimal medium induces, growth and cbb3-Cox defects. Alleviation of these defects by addition of redox-active chemicals indicates that absence of DsbA perturbs cellular redox homeostasis required for the production of an active cbb3-Cox, especially in enriched medium where bioavailable Cu2+ is scarce. This is the first report describingmore »
- Authors:
-
- Univ. of Pennsylvania, Philadelphia, PA (United States)
- Albert-Ludwigs-Universität Freiburg (Germany)
- Publication Date:
- Research Org.:
- Univ. of Pennsylvania, Philadelphia, PA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences, and Biosciences Division
- OSTI Identifier:
- 1510498
- Grant/Contract Number:
- FG02-91ER20052
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Frontiers in Microbiology
- Additional Journal Information:
- Journal Volume: 8; Journal ID: ISSN 1664-302X
- Publisher:
- Frontiers Research Foundation
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; disulfide bond formation; copper homeostasis; cbb3-type cytochrome c oxidase biogenesis; Rhodobacter capsulatus; respiration; photosynthesis
Citation Formats
Onder, Ozlem, Verissimo, Andreia F., Khalfaoui-Hassani, Bahia, Peters, Annette, Koch, Hans-Georg, and Daldal, Fevzi. Absence of Thiol-Disulfide Oxidoreductase DsbA Impairs cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus. United States: N. p., 2017.
Web. doi:10.3389/fmicb.2017.02576.
Onder, Ozlem, Verissimo, Andreia F., Khalfaoui-Hassani, Bahia, Peters, Annette, Koch, Hans-Georg, & Daldal, Fevzi. Absence of Thiol-Disulfide Oxidoreductase DsbA Impairs cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus. United States. https://doi.org/10.3389/fmicb.2017.02576
Onder, Ozlem, Verissimo, Andreia F., Khalfaoui-Hassani, Bahia, Peters, Annette, Koch, Hans-Georg, and Daldal, Fevzi. Thu .
"Absence of Thiol-Disulfide Oxidoreductase DsbA Impairs cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus". United States. https://doi.org/10.3389/fmicb.2017.02576. https://www.osti.gov/servlets/purl/1510498.
@article{osti_1510498,
title = {Absence of Thiol-Disulfide Oxidoreductase DsbA Impairs cbb3-Type Cytochrome c Oxidase Biogenesis in Rhodobacter capsulatus},
author = {Onder, Ozlem and Verissimo, Andreia F. and Khalfaoui-Hassani, Bahia and Peters, Annette and Koch, Hans-Georg and Daldal, Fevzi},
abstractNote = {The thiol-disulfide oxidoreductase DsbA carries out oxidative folding of extra-cytoplasmic proteins by catalyzing the formation of intramolecular disulfide bonds. It has an important role in various cellular functions, including cell division. The purple non-sulfur bacterium Rhodobacter capsulatus mutants lacking DsbA show severe temperature-sensitive and medium-dependent respiratory growth defects. In the presence of oxygen, at normal growth temperature (35°C), DsbA- mutants form colonies on minimal medium, but they do not grow on enriched medium where cells elongate and lyse. At lower temperatures (i.e., 25°C), cells lacking DsbA grow normally in both minimum and enriched media, however, they do not produce the cbb3-type cytochrome c oxidase (cbb3-Cox) on enriched medium. Availability of chemical oxidants (e.g., Cu2+ or a mixture of cysteine and cystine) in the medium becomes critical for growth and cbb3-Cox production in the absence of DsbA. Indeed, addition of Cu2+ to the enriched medium suppresses, and conversely, omission of Cu2+ from the minimal medium induces, growth and cbb3-Cox defects. Alleviation of these defects by addition of redox-active chemicals indicates that absence of DsbA perturbs cellular redox homeostasis required for the production of an active cbb3-Cox, especially in enriched medium where bioavailable Cu2+ is scarce. This is the first report describing that DsbA activity is required for full respiratory capability of R. capsulatus, and in particular, for proper biogenesis of its cbb3-Cox. We propose that absence of DsbA, besides impairing the maturation of the c-type cytochrome subunits, also affects the incorporation of Cu into the catalytic subunit of cbb3-Cox. Defective high affinity Cu acquisition pathway, which includes the MFS-type Cu importer CcoA, and lower production of the c-type cytochrome subunits lead together to improper assembly and degradation of cbb3-Cox.},
doi = {10.3389/fmicb.2017.02576},
journal = {Frontiers in Microbiology},
number = ,
volume = 8,
place = {United States},
year = {Thu Dec 21 00:00:00 EST 2017},
month = {Thu Dec 21 00:00:00 EST 2017}
}
Web of Science
Works referenced in this record:
The interplay between the disulfide bond formation pathway and cytochrome c maturation in Escherichia coli
journal, May 2012
- Mavridou, Despoina A. I.; Ferguson, Stuart J.; Stevens, Julie M.
- FEBS Letters, Vol. 586, Issue 12
Membrane-associated cytochrome cy of Rhodobacter capsulatus is an electron carrier from the cytochrome bc1 complex to the cytochrome c oxidase during respiration.
journal, February 1995
- Hochkoeppler, A.; Jenney, F. E.; Lang, S. E.
- Journal of Bacteriology, Vol. 177, Issue 3
Roles of the ccoGHIS gene products in the biogenesis of the cbb3-type cytochrome c oxidase
journal, March 2000
- Koch, Hans-Georg; Winterstein, Christine; Saribas, A. Sami
- Journal of Molecular Biology, Vol. 297, Issue 1
Intracytoplasmic Copper Homeostasis Controls Cytochrome c Oxidase Production
journal, January 2014
- Ekici, Seda; Turkarslan, Serdar; Pawlik, Grzegorz
- mBio, Vol. 5, Issue 1
Structure and mechanisms of the DsbB–DsbA disulfide bond generation machine
journal, April 2008
- Inaba, Kenji; Ito, Koreaki
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1783, Issue 4
The thioreduction component CcmG confers efficiency and the heme ligation component CcmH ensures stereo-specificity during cytochrome c maturation
journal, June 2017
- Verissimo, Andreia F.; Khalfaoui-Hassani, Bahia; Hwang, Josephine
- Journal of Biological Chemistry, Vol. 292, Issue 32
The ScoI homologue SenC is a copper binding protein that interacts directly with the cbb3-type cytochrome oxidase in Rhodobacter capsulatus
journal, November 2012
- Lohmeyer, Eva; Schröder, Sebastian; Pawlik, Grzegorz
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1817, Issue 11
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
journal, November 1987
- Schägger, Hermann; von Jagow, Gebhard
- Analytical Biochemistry, Vol. 166, Issue 2
A Requirement for Sodium in the Growth of Rhodopseudomonas spheroides
journal, June 1960
- Sistrom, W. R.
- Journal of General Microbiology, Vol. 22, Issue 3
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
journal, August 1970
- Laemmli, U. K.
- Nature, Vol. 227, Issue 5259, p. 680-685
Copper Stress Causes an in Vivo Requirement for the Escherichia coli Disulfide Isomerase DsbC
journal, August 2005
- Hiniker, Annie; Collet, Jean-Francois; Bardwell, James C. A.
- Journal of Biological Chemistry, Vol. 280, Issue 40
Involvement of SenC in Assembly of Cytochrome c Oxidase in Rhodobacter capsulatus
journal, November 2005
- Swem, D. L.; Swem, L. R.; Setterdahl, A.
- Journal of Bacteriology, Vol. 187, Issue 23
Cytochrome c biogenesis System I: An intricate process catalyzed by a maturase supercomplex?
journal, July 2014
- Verissimo, Andreia F.; Daldal, Fevzi
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1837, Issue 7
Cytochrome c biogenesis: the Ccm system
journal, June 2010
- Sanders, Carsten; Turkarslan, Serdar; Lee, Dong-Woo
- Trends in Microbiology, Vol. 18, Issue 6
Structure and Function of DsbA, a Key Bacterial Oxidative Folding Catalyst
journal, May 2011
- Shouldice, Stephen R.; Heras, Begoña; Walden, Patricia M.
- Antioxidants & Redox Signaling, Vol. 14, Issue 9
Influence of quercetin, a bioflavonoid, on the toxicity of copper to Fusarium culmorum
journal, May 1998
- Park,
- Letters in Applied Microbiology, Vol. 26, Issue 5
Biogenesis of cbb3-type cytochrome c oxidase in Rhodobacter capsulatus
journal, June 2012
- Ekici, Seda; Pawlik, Grzegorz; Lohmeyer, Eva
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1817, Issue 6
CcmI Subunit of CcmFHI Heme Ligation Complex Functions as an Apocytochrome c Chaperone during c -Type Cytochrome Maturation
journal, September 2011
- Verissimo, Andreia F.; Yang, Honghui; Wu, Xiaomin
- Journal of Biological Chemistry, Vol. 286, Issue 47
Adaptation of aerobic respiration to low O2 environments
journal, August 2011
- Han, H.; Hemp, J.; Pace, L. A.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 34
Adaptation to Oxygen: ROLE OF TERMINAL OXIDASES IN PHOTOSYNTHESIS INITIATION IN THE PURPLE PHOTOSYNTHETIC BACTERIUM, RUBRIVIVAX GELATINOSUS
journal, March 2010
- Hassani, Bahia Khalfaoui; Steunou, Anne-Soisig; Liotenberg, Sylviane
- Journal of Biological Chemistry, Vol. 285, Issue 26
An essential role for DsbA in cytochromec synthesis and formate-dependent nitrite reduction byEscherichia coli K-12
journal, October 1995
- Metheringham, Rachael; Griffiths, Lesley; Crooke, Helen
- Archives of Microbiology, Vol. 164, Issue 4
In vitro insertional mutagenesis with a selectable DNA fragment
journal, September 1984
- Prentki, Pierre; Krisch, Henry M.
- Gene, Vol. 29, Issue 3
Mutagenesis of methionine-183 drastically affects the physicochemical properties of cytochrome c1 of the bc1 complex of Rhodobacter capsulatus
journal, December 1992
- Gray, Kevin A.; Davidson, Edgar; Daldal, Fevzi
- Biochemistry, Vol. 31, Issue 47
The Structure of cbb3 Cytochrome Oxidase Provides Insights into Proton Pumping
journal, June 2010
- Buschmann, S.; Warkentin, E.; Xie, H.
- Science, Vol. 329, Issue 5989
The Disulfide Bond Formation Pathway Is Essential for Anaerobic Growth of Escherichia coli
journal, May 2017
- Meehan, Brian M.; Landeta, Cristina; Boyd, Dana
- Journal of Bacteriology, Vol. 199, Issue 16
A Temperature-Dependent Switch from Chaperone to Protease in a Widely Conserved Heat Shock Protein
journal, April 1999
- Spiess, Christoph; Beil, Alexandra; Ehrmann, Michael
- Cell, Vol. 97, Issue 3
Ornithine lipid is required for optimal steady-state amounts of c-type cytochromes in Rhodobacter capsulatus
journal, July 2006
- Aygun-Sunar, Semra; Mandaci, Sevnur; Koch, Hans-George
- Molecular Microbiology, Vol. 61, Issue 2
Unexpected Elevated Production of Aquifex aeolicus Cytochrome c 555 in Escherichia coli Cells Lacking Disulfide Oxidoreductases
journal, January 2005
- Kojima, Nobusuke; Yamanaka, Masaru; Ichiki, Shin-ichi
- Bioscience, Biotechnology, and Biochemistry, Vol. 69, Issue 7
Multi-step Assembly Pathway of the cbb3-type Cytochrome c Oxidase Complex
journal, February 2006
- Kulajta, Carmen; Thumfart, Jörg Oliver; Haid, Sybille
- Journal of Molecular Biology, Vol. 355, Issue 5
Biochemical Physiology of a Respiration-Deficient Mutant of the Photosynthetic Bacterium Rhodopseudomonas capsulata
journal, April 1972
- Marrs, B.; Stahl, C. L.; Lien, S.
- Proceedings of the National Academy of Sciences, Vol. 69, Issue 4
Unexpected Elevated Production of Aquifex aeolicus Cytochrome c 555 in Escherichia coli Cells Lacking Disulfide Oxidoreductases
journal, January 2005
- Kojima, Nobusuke; Yamanaka, Masaru; Ichiki, Shin-ichi
- Bioscience, Biotechnology, and Biochemistry, Vol. 69, Issue 7
Structure and Function of DsbA, a Key Bacterial Oxidative Folding Catalyst
journal, May 2011
- Shouldice, Stephen R.; Heras, Begoña; Walden, Patricia M.
- Antioxidants & Redox Signaling, Vol. 14, Issue 9
Overproduction or Absence of the Periplasmic Protease DegP Severely Compromises Bacterial Growth in the Absence of the Dithiol: Disulfide Oxidoreductase DsbA
journal, January 2008
- Önder, Özlem; Turkarslan, Serdar; Sun, David
- Molecular & Cellular Proteomics, Vol. 7, Issue 5
Uncovering the Transmembrane Metal Binding Site of the Novel Bacterial Major Facilitator Superfamily-Type Copper Importer CcoA
journal, January 2016
- Khalfaoui-Hassani, Bahia; Verissimo, Andreia F.; Koch, Hans-Georg
- mBio, Vol. 7, Issue 1
Cytochrome c2 is not essential for photosynthetic growth of Rhodopseudomonas capsulata
journal, April 1986
- Daldal, F.; Cheng, S.; Applebaum, J.
- Proceedings of the National Academy of Sciences, Vol. 83, Issue 7
The Dithiol:Disulfide Oxidoreductases DsbA and DsbB of Rhodobacter capsulatus Are Not Directly Involved in Cytochrome c Biogenesis, but Their Inactivation Restores the Cytochrome c Biogenesis Defect of CcdA-Null Mutants
journal, June 2003
- Deshmukh, M.; Turkarslan, S.; Astor, D.
- Journal of Bacteriology, Vol. 185, Issue 11
Isolation and Characterization of a Two-Subunit Cytochrome b − c 1 Subcomplex from Rhodobacter capsulatus and Reconstitution of Its Ubihydroquinone Oxidation (Q o ) Site with Purified Fe-S Protein Subunit †
journal, November 1998
- Valkova-Valchanova, Maria B.; Saribas, A. Sami; Gibney, Brian R.
- Biochemistry, Vol. 37, Issue 46
The roles of Rhodobacter sphaeroides copper chaperones PCuAC and Sco (PrrC) in the assembly of the copper centers of the aa3-type and the cbb3-type cytochrome c oxidases
journal, June 2012
- Thompson, Audie K.; Gray, Jimmy; Liu, Aimin
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1817, Issue 6
Membrane-associated cytochrome cy of Rhodobacter capsulatus is an electron carrier from the cytochrome bc1 complex to the cytochrome c oxidase during respiration.
journal, February 1995
- Hochkoeppler, A.; Jenney, F. E.; Lang, S. E.
- Journal of Bacteriology, Vol. 177, Issue 3
The interplay between the disulfide bond formation pathway and cytochrome c maturation in Escherichia coli
journal, May 2012
- Mavridou, Despoina A. I.; Ferguson, Stuart J.; Stevens, Julie M.
- FEBS Letters, Vol. 586, Issue 12
Novel Transporter Required for Biogenesis of cbb3-Type Cytochrome c Oxidase in Rhodobacter capsulatus
journal, January 2012
- Ekici, Seda; Yang, Honghui; Koch, Hans-Georg
- mBio, Vol. 3, Issue 1
Cytochrome c biogenesis: the Ccm system
journal, June 2010
- Sanders, Carsten; Turkarslan, Serdar; Lee, Dong-Woo
- Trends in Microbiology, Vol. 18, Issue 6
A Requirement for Sodium in the Growth of Rhodopseudomonas spheroides
journal, June 1960
- Sistrom, W. R.
- Journal of General Microbiology, Vol. 22, Issue 3
The roles of Rhodobacter sphaeroides copper chaperones PCuAC and Sco (PrrC) in the assembly of the copper centers of the aa3-type and the cbb3-type cytochrome c oxidases
journal, June 2012
- Thompson, Audie K.; Gray, Jimmy; Liu, Aimin
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1817, Issue 6
In vitro insertional mutagenesis with a selectable DNA fragment
journal, September 1984
- Prentki, Pierre; Krisch, Henry M.
- Gene, Vol. 29, Issue 3
Adaptation of aerobic respiration to low O2 environments
journal, August 2011
- Han, H.; Hemp, J.; Pace, L. A.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 34
Map of genes for carotenoid and bacteriochlorophyll biosynthesis in Rhodopseudomonas capsulata.
journal, January 1976
- Yen, H. C.; Marrs, B.
- Journal of Bacteriology, Vol. 126, Issue 2
Control of DegP-Dependent Degradation of c-Type Cytochromes by Heme and the Cytochrome c Maturation System in Escherichia coli
journal, July 2007
- Gao, T.; O'Brian, M. R.
- Journal of Bacteriology, Vol. 189, Issue 17
Structure and mechanisms of the DsbB–DsbA disulfide bond generation machine
journal, April 2008
- Inaba, Kenji; Ito, Koreaki
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1783, Issue 4
A novel scenario for the evolution of haem–copper oxygen reductases
journal, June 2001
- Pereira, Manuela M.; Santana, Margarida; Teixeira, Miguel
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1505, Issue 2-3
Improved broad-host-range plasmids for DNA cloning in Gram-negative bacteria
journal, October 1988
- Keen, N. T.; Tamaki, S.; Kobayashi, D.
- Gene, Vol. 70, Issue 1
How Replacements of the 12 Conserved Histidines of Subunit I Affect Assembly, Cofactor Binding, and Enzymatic Activity of the Bradyrhizobium japonicum cbb 3 -type Oxidase
journal, March 1998
- Zufferey, Rachel; Arslan, Engin; Thöny-Meyer, Linda
- Journal of Biological Chemistry, Vol. 273, Issue 11
Biogenesis of cbb3-type cytochrome c oxidase in Rhodobacter capsulatus
journal, June 2012
- Ekici, Seda; Pawlik, Grzegorz; Lohmeyer, Eva
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1817, Issue 6
Characterization of the gene transfer agent made by an overproducer mutant of Rhodopseudomonas capsulata
journal, June 1979
- Yen, H. C.; Hu, N. T.; Marrs, B. L.
- Journal of Molecular Biology, Vol. 131, Issue 2
The branched respiratory system of photosynthetically grown Rhodopseudomonas capsulata
journal, March 1976
- La Monica, R. F.; Marrs, B. L.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 423, Issue 3
Size of the amino acid side chain at position 158 of cytochrome b is critical for an active cytochrome bc1 complex and for photosynthetic growth of Rhodobacter capsulatus.
journal, January 1991
- Atta-Asafo-Adjei, E.; Daldal, F.
- Proceedings of the National Academy of Sciences, Vol. 88, Issue 2
An improved staining procedure for the detection of the peroxidase activity of cytochrome P-450 on sodium dodecyl sulfate polyacrylamide gels
journal, September 1976
- Thomas, Paul E.; Ryan, Dene; Levin, Wayne
- Analytical Biochemistry, Vol. 75, Issue 1
Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress
journal, July 2014
- Giuffrè, Alessandro; Borisov, Vitaliy B.; Arese, Marzia
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1837, Issue 7
The Cytochrome c Maturation Components CcmF, CcmH, and CcmI Form a Membrane-integral Multisubunit Heme Ligation Complex
journal, August 2008
- Sanders, Carsten; Turkarslan, Serdar; Lee, Dong-Woo
- Journal of Biological Chemistry, Vol. 283, Issue 44
Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form
journal, December 1991
- Schägger, Hermann; von Jagow, Gebhard
- Analytical Biochemistry, Vol. 199, Issue 2
The essential cell division protein FtsN contains a critical disulfide bond in a non‐essential domain
journal, December 2016
- Meehan, Brian M.; Landeta, Cristina; Boyd, Dana
- Molecular Microbiology, Vol. 103, Issue 3
Roles of the Soluble Cytochrome c2 and Membrane-Associated Cytochrome cy of Rhodobacter capsulatus in Photosynthetic Electron Transfer
journal, March 1994
- Jenney, Francis E.; Prince, Roger C.; Daldal, Fevzi
- Biochemistry, Vol. 33, Issue 9
Plasmids related to the broad host range vector, pRK290, useful for gene cloning and for monitoring gene expression
journal, March 1985
- Ditta, Gary; Schmidhauser, Thomas; Yakobson, Emanuel
- Plasmid, Vol. 13, Issue 2
Genetic Evidence for Parallel Pathways of Chaperone Activity in the Periplasm of Escherichia coli
journal, December 2001
- Rizzitello, A. E.; Harper, J. R.; Silhavy, T. J.
- Journal of Bacteriology, Vol. 183, Issue 23
Biochemical Physiology of a Respiration-Deficient Mutant of the Photosynthetic Bacterium Rhodopseudomonas capsulata
journal, April 1972
- Marrs, B.; Stahl, C. L.; Lien, S.
- Proceedings of the National Academy of Sciences, Vol. 69, Issue 4
Active Site of Cytochrome cbb 3
journal, February 2009
- Rauhamäki, Virve; Bloch, Dmitry A.; Verkhovsky, Michael I.
- Journal of Biological Chemistry, Vol. 284, Issue 17
Mutagenesis of methionine-183 drastically affects the physicochemical properties of cytochrome c1 of the bc1 complex of Rhodobacter capsulatus
journal, December 1992
- Gray, Kevin A.; Davidson, Edgar; Daldal, Fevzi
- Biochemistry, Vol. 31, Issue 47
The Structure of cbb3 Cytochrome Oxidase Provides Insights into Proton Pumping
journal, June 2010
- Buschmann, S.; Warkentin, E.; Xie, H.
- Science, Vol. 329, Issue 5989
Multi-step Assembly Pathway of the cbb3-type Cytochrome c Oxidase Complex
journal, February 2006
- Kulajta, Carmen; Thumfart, Jörg Oliver; Haid, Sybille
- Journal of Molecular Biology, Vol. 355, Issue 5
Missense Mutations in Cytochrome c Maturation Genes Provide New Insights into Rhodobacter capsulatus cbb 3 -Type Cytochrome c Oxidase Biogenesis
journal, November 2012
- Ekici, Seda; Jiang, Xinpei; Koch, Hans-Georg
- Journal of Bacteriology, Vol. 195, Issue 2
The [2Fe-2S] Cluster E m as an Indicator of the Iron-Sulfur Subunit Position in the Ubihydroquinone Oxidation Site of the Cytochrome bc 1 Complex
journal, November 2001
- Darrouzet, Elisabeth; Valkova-Valchanova, Maria; Daldal, Fevzi
- Journal of Biological Chemistry, Vol. 277, Issue 5
Isolation and Characterization of a Two-Subunit Cytochrome b − c 1 Subcomplex from Rhodobacter capsulatus and Reconstitution of Its Ubihydroquinone Oxidation (Q o ) Site with Purified Fe-S Protein Subunit †
journal, November 1998
- Valkova-Valchanova, Maria B.; Saribas, A. Sami; Gibney, Brian R.
- Biochemistry, Vol. 37, Issue 46
Stability of the cbb3-Type Cytochrome Oxidase Requires Specific CcoQ-CcoP Interactions
journal, June 2008
- Peters, A.; Kulajta, C.; Pawlik, G.
- Journal of Bacteriology, Vol. 190, Issue 16
Rhodobacter capsulatus Contains a Novel cb-Type Cytochrome c Oxidase without a CuA Center
journal, March 1994
- Gray, Kevin A.; Grooms, Michael; Myllykallio, Hannu
- Biochemistry, Vol. 33, Issue 10
The essential cell division protein FtsN contains a critical disulfide bond in a non‐essential domain
journal, December 2016
- Meehan, Brian M.; Landeta, Cristina; Boyd, Dana
- Molecular Microbiology, Vol. 103, Issue 3
Ornithine lipid is required for optimal steady-state amounts of c-type cytochromes in Rhodobacter capsulatus
journal, July 2006
- Aygun-Sunar, Semra; Mandaci, Sevnur; Koch, Hans-George
- Molecular Microbiology, Vol. 61, Issue 2
Isolation and Characterization of Rhodobacter capsulatus Mutants Affected in Cytochromecbb
3 Oxidase Activity
journal, January 1998
- Koch, Hans-Georg; Hwang, Olivia; Daldal, Fevzi
- Journal of Bacteriology, Vol. 180, Issue 4
Mobile Cytochrome c2 and Membrane-Anchored Cytochrome cy Are Both Efficient Electron Donors to the cbb3- and aa3-Type Cytochrome c Oxidases during Respiratory Growth of Rhodobacter sphaeroides
journal, March 2001
- Daldal, F.; Mandaci, S.; Winterstein, C.
- Journal of Bacteriology, Vol. 183, Issue 6
Rhodobacter capsulatus Contains a Novel cb-Type Cytochrome c Oxidase without a CuA Center
journal, March 1994
- Gray, Kevin A.; Grooms, Michael; Myllykallio, Hannu
- Biochemistry, Vol. 33, Issue 10
Cytochrome bd oxidase and bacterial tolerance to oxidative and nitrosative stress
journal, July 2014
- Giuffrè, Alessandro; Borisov, Vitaliy B.; Arese, Marzia
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1837, Issue 7
Characterization of the gene transfer agent made by an overproducer mutant of Rhodopseudomonas capsulata
journal, June 1979
- Yen, H. C.; Hu, N. T.; Marrs, B. L.
- Journal of Molecular Biology, Vol. 131, Issue 2
Cytochrome c2 is not essential for photosynthetic growth of Rhodopseudomonas capsulata
journal, April 1986
- Daldal, F.; Cheng, S.; Applebaum, J.
- Proceedings of the National Academy of Sciences, Vol. 83, Issue 7
Fluorescence-assisted sequential insertion of transgenes (FASIT): an approach for increasing specific productivity in mammalian cells
journal, July 2020
- Bravo, Felipe E.; Parra, Natalie C.; Camacho, Frank
- Scientific Reports, Vol. 10, Issue 1
The branched respiratory system of photosynthetically grown Rhodopseudomonas capsulata
journal, March 1976
- La Monica, R. F.; Marrs, B. L.
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 423, Issue 3
Improved broad-host-range plasmids for DNA cloning in Gram-negative bacteria
journal, October 1988
- Keen, N. T.; Tamaki, S.; Kobayashi, D.
- Gene, Vol. 70, Issue 1
Compensatory thio-redox interactions between DsbA, CcdA and CcmG unveil the apocytochrome c holdase role of CcmG during cytochrome c maturation
journal, November 2008
- Turkarslan, Serdar; Sanders, Carsten; Ekici, Seda
- Molecular Microbiology, Vol. 70, Issue 3
Cooperation between two periplasmic copper chaperones is required for full activity of the cbb 3 -type cytochrome c oxidase and copper homeostasis in Rhodobacter capsulatus : PccA-SenC interactions determine
journal, February 2016
- Trasnea, Petru-Iulian; Utz, Marcel; Khalfaoui-Hassani, Bahia
- Molecular Microbiology, Vol. 100, Issue 2
The superfamily of heme-copper respiratory oxidases.
journal, September 1994
- García-Horsman, J. A.; Barquera, B.; Rumbley, J.
- Journal of Bacteriology, Vol. 176, Issue 18
How Replacements of the 12 Conserved Histidines of Subunit I Affect Assembly, Cofactor Binding, and Enzymatic Activity of the Bradyrhizobium japonicum cbb 3 -type Oxidase
journal, March 1998
- Zufferey, Rachel; Arslan, Engin; Thöny-Meyer, Linda
- Journal of Biological Chemistry, Vol. 273, Issue 11
Size of the amino acid side chain at position 158 of cytochrome b is critical for an active cytochrome bc1 complex and for photosynthetic growth of Rhodobacter capsulatus.
journal, January 1991
- Atta-Asafo-Adjei, E.; Daldal, F.
- Proceedings of the National Academy of Sciences, Vol. 88, Issue 2
Roles of the ccoGHIS gene products in the biogenesis of the cbb3-type cytochrome c oxidase
journal, March 2000
- Koch, Hans-Georg; Winterstein, Christine; Saribas, A. Sami
- Journal of Molecular Biology, Vol. 297, Issue 1
Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata.
journal, March 1980
- Scolnik, P. A.; Walker, M. A.; Marrs, B. L.
- Journal of Biological Chemistry, Vol. 255, Issue 6
Works referencing / citing this record:
Cu Transport by the Extended Family of CcoA-like Transporters (CalT) in Proteobacteria
journal, February 2019
- Zhang, Yang; Blaby-Haas, Crysten E.; Steimle, Stefan
- Scientific Reports, Vol. 9, Issue 1