Spectrum of chronic kidney disease in China: A national study based on hospitalized patients from 2010 to 2015

Journal Article · 30 April 2019 · Nephrology

DOI: https://doi.org/10.1111/nep.13489 · OSTI ID:1510097

Huang, Yu‐Ming ^[1]; Xu, Damin ^[1]; Long, Jianyan ^[2]; Shi, Ying ^[2]; Zhang, Luxia ^[3]; Wang, Haibo ^[4]; Levin, Adeera ^[5]; Zhao, Ming‐Hui ^[6]

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1. Renal Division, Department of Medicine Peking University First Hospital, Peking University Institute of Nephrology Beijing China
2. China Standard Medical Information Research Center Shenzhen China
3. Renal Division, Department of Medicine Peking University First Hospital, Peking University Institute of Nephrology Beijing China, Peking University, Center for Data Science in Health and Medicine Beijing China
4. China Standard Medical Information Research Center Shenzhen China, Clinical Trial Unit First Affiliated Hospital of Sun Yat‐Sen University Guangzhou China
5. University of British Columbia Vancouver British Columbia Canada
6. Renal Division, Department of Medicine Peking University First Hospital, Peking University Institute of Nephrology Beijing China, Peking‐Tsinghua Center for Life Sciences Beijing PR China

ABSTRACT Aim To investigate the spectrum of chronic kidney disease (CKD) in China. Methods We used a large national in‐patient database covering 878 class three hospitals and involving 64.7 million adult patients in China from 2010 to 2015. The class 3 hospital in China is ranked as the top tier of medical system in China with at least 500 beds and the accreditation from health authorities. The specific causes of CKD were extracted from the International Classification of Diseases‐10 codes of discharge diagnoses. Results A total of 4.5% of hospitalized patients (1.8 million) were identified as CKD, with an increased percentage from 2010 (3.7%) to 2015 (4.7%). Increasing trends of diabetic kidney disease and hypertensive nephropathy were observed from 2010 to 2015 (19.5% vs 24.3% and 11.5% vs 15.9%, respectively), especially for urban residents from north China. The proportion of obstructive nephropathy also increased gradually (10.3% in 2010 vs 15.6% in 2015) and constituted another important cause of CKD for patients, especially for those from south China and rural residents. Conclusion The spectrum of CKD is changing in China, with variations over time and geographic regions, which has implication regarding developing the prevention strategy of CKD.

• Sponsoring Organization: USDOE
• OSTI ID: 1510097
• Journal Information: Nephrology, Journal Name: Nephrology Vol. 24 Journal Issue: 7; ISSN 1320-5358
• Publisher: Wiley-BlackwellCopyright Statement
• Country of Publication: Country unknown/Code not available
• Language: English