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Title: Biosynthesis and secretion of the microbial sulfated peptide RaxX and binding to the rice XA21 immune receptor

Journal Article · · Proceedings of the National Academy of Sciences of the United States of America
ORCiD logo [1]; ORCiD logo [2];  [3];  [4]; ORCiD logo [1];  [1];  [3];  [3];  [1];  [1];  [5];  [4]; ORCiD logo [2]
  1. Department of Plant Pathology, University of California, Davis, CA 95616,, The Genome Center, University of California, Davis, CA 95616,
  2. Department of Plant Pathology, University of California, Davis, CA 95616,, The Genome Center, University of California, Davis, CA 95616,, Feedstocks Division, Joint Bioenergy Institute, Emeryville, CA 94608,
  3. Technology Division, Joint Bioenergy Institute, Emeryville, CA 94608,
  4. Gregor Mendel Institute, Austrian Academy of Sciences, 1030 Vienna, Austria,
  5. Department of Microbiology &, Molecular Genetics, University of California, Davis, CA 95616
+ Show Author Affiliations

Significance Despite the importance of immune receptors in the biology of plants and animals, the precise biochemical mechanisms leading to the biosynthesis and secretion of the peptide activators of these immune receptors remain unexplored. Here, we describe the biosynthesis, processing, and secretion of a peptide activator that binds a rice immune receptor. Our studies also reveal that this peptide activator is a member of an important class of peptides present in both eukaryotic and prokaryotic species. Thus, these results provide a major advance in our knowledge of the biology of peptide ligands.

Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER)
Grant/Contract Number:
AC02-05CH11231
OSTI ID:
1505236
Journal Information:
Proceedings of the National Academy of Sciences of the United States of America, Journal Name: Proceedings of the National Academy of Sciences of the United States of America Journal Issue: 17 Vol. 116; ISSN 0027-8424
Publisher:
Proceedings of the National Academy of SciencesCopyright Statement
Country of Publication:
United States
Language:
English

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