Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction

Survase, Shrikant A.; Zebroski, Ryan; Bayuadri, Cosmas; Wang, Ziyu; Adamos, Georgios; Nagy, Grigore; Pylkkanen, Vesa

doi:10.1016/j.biortech.2019.02.024

Title: Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction

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Abstract

The aim was to demonstrate an industrially relevant pilot scale integrated process to produce butanol and other solvents from lignocellulosic sugars produced with AVAP® biomass fractionation technology from southern pine wood. The concentrated sugars were concurrently fermented using genetically engineered Clostridium acetobutylicum to n-butanol, acetone, isopropanol and ethanol in continuous membrane assisted cell recycle fermentation with steady-state solvent productivity exceeding 10 g/L/h. The solvents from the cell free permeate were recovered with extractant of butyl butyrate in a continuous liquid-liquid extraction column and aqueous product (raffinate) along with unused sugars, nutrients, and metabolic intermediates were recycled back to the fermentors. The total solvent yield approached 0.30 g/g sugars.

Authors:

Survase, Shrikant A. ^[1]; Zebroski, Ryan ^[1]; Bayuadri, Cosmas ^[1]; Wang, Ziyu ^[1]; Adamos, Georgios ^[2]; Nagy, Grigore ^[3]; Pylkkanen, Vesa ^[4]

American Process Inc., Thomaston, GA (United States)
API Europe, Athens (Greece)
American Process Inc., Cluj-Napoca (Romania)
American Process Inc., Atlanta, GA (United States)

Publication Date:: Tue Feb 05 00:00:00 EST 2019

Research Org.:: American Process Inc., Atlanta, GA (United States)

Sponsoring Org.:: USDOE Office of Energy Efficiency and Renewable Energy (EERE), Sustainable Transportation Office. Bioenergy Technologies Office

OSTI Identifier:: 1504134

Alternate Identifier(s):: OSTI ID: 1778513

Grant/Contract Number:: EE0006879

Resource Type:: Accepted Manuscript

Journal Name:: Bioresource Technology

Additional Journal Information:: Journal Volume: 280; Journal ID: ISSN 0960-8524

Publisher:: Elsevier

Country of Publication:: United States

Language:: English

Subject:: 09 BIOMASS FUELS; continuous butanol fermentation; butyl butyrate extraction; high cell density culture; membrane recycle fermentor; pine sugars

Citation Formats


                    Survase, Shrikant A., Zebroski, Ryan, Bayuadri, Cosmas, Wang, Ziyu, Adamos, Georgios, Nagy, Grigore, and Pylkkanen, Vesa. Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction.  United States: N. p., 2019. 
Web.  doi:10.1016/j.biortech.2019.02.024.

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                    Survase, Shrikant A., Zebroski, Ryan, Bayuadri, Cosmas, Wang, Ziyu, Adamos, Georgios, Nagy, Grigore, & Pylkkanen, Vesa. Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction.  United States.  https://doi.org/10.1016/j.biortech.2019.02.024

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                    Survase, Shrikant A., Zebroski, Ryan, Bayuadri, Cosmas, Wang, Ziyu, Adamos, Georgios, Nagy, Grigore, and Pylkkanen, Vesa. Tue .  
"Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction".  United States.  https://doi.org/10.1016/j.biortech.2019.02.024.  https://www.osti.gov/servlets/purl/1504134.

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@article{osti_1504134,

  title        = {Membrane assisted continuous production of solvents with integrated solvent removal using liquid-liquid extraction},

  author       = {Survase, Shrikant A. and Zebroski, Ryan and Bayuadri, Cosmas and Wang, Ziyu and Adamos, Georgios and Nagy, Grigore and Pylkkanen, Vesa},

  abstractNote = {The aim was to demonstrate an industrially relevant pilot scale integrated process to produce butanol and other solvents from lignocellulosic sugars produced with AVAP® biomass fractionation technology from southern pine wood. The concentrated sugars were concurrently fermented using genetically engineered Clostridium acetobutylicum to n-butanol, acetone, isopropanol and ethanol in continuous membrane assisted cell recycle fermentation with steady-state solvent productivity exceeding 10 g/L/h. The solvents from the cell free permeate were recovered with extractant of butyl butyrate in a continuous liquid-liquid extraction column and aqueous product (raffinate) along with unused sugars, nutrients, and metabolic intermediates were recycled back to the fermentors. The total solvent yield approached 0.30 g/g sugars.},

  doi          = {10.1016/j.biortech.2019.02.024},

  journal      = {Bioresource Technology},

  number       = ,

  volume       = 280,

  place        = {United States},

  year         = {Tue Feb 05 00:00:00 EST 2019},

  month        = {Tue Feb 05 00:00:00 EST 2019}

}

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https://doi.org/10.1016/j.biortech.2019.02.024

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