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Title: A 3D Computational Head Model Under Dynamic Head Rotation and Head Extension Validated Using Live Human Brain Data, Including the Falx and the Tentorium

Journal Article · · Annals of Biomedical Engineering
 [1]; ORCiD logo [1];  [2];  [1];  [2];  [3];  [1];  [4]; ORCiD logo [1]
  1. Johns Hopkins Univ., Baltimore, MD (United States)
  2. The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD (United States)
  3. National Institutes of Health Clinical Center, Bethesda, MD (United States)
  4. Washington Univ. in St. Louis, St. Louis, MO (United States)

We employ an advanced 3D computational model of the head with high anatomical fidelity, together with measured tissue properties, to assess the consequences of dynamic loading to the head in two distinct modes: head rotation and head extension. We use a subject-specific computational head model, using the material point method, built from T1 magnetic resonance images, and considering the anisotropic properties of the white matter which can predict strains in the brain under large rotational accelerations. The material model now includes the shear anisotropy of the white matter. We validate the model under head rotation and head extension motions using live human data, and advance a prior version of the model to include biofidelic falx and tentorium. Furthermore we then examine the consequences of incorporating the falx and tentorium in terms of the predictions from the computational head model.

Research Organization:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
National Institutes of Health; USDOE
Grant/Contract Number:
89233218CNA000001
OSTI ID:
1495175
Report Number(s):
LA-UR--19-20972
Journal Information:
Annals of Biomedical Engineering, Journal Name: Annals of Biomedical Engineering Journal Issue: 9 Vol. 47; ISSN 0090-6964
Publisher:
SpringerCopyright Statement
Country of Publication:
United States
Language:
English

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Cited By (1)

Nonlinear Dynamical Behavior of the Deep White Matter during Head Impact journal July 2019