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Title: Microscale and Nanoscale Electrophotonic Diagnostic Devices

Abstract

Detecting and identifying infectious agents and potential pathogens in complex environments and characterizing their mode of action is a critical need. Traditional diagnostics have targeted a single characteristic, e.g. spectral response, surface receptor, mass, intrinsic conductivity, etc. However, advances in detection technologies have identified emerging approaches in which multiple modes of action are combined to obtain enhanced performance characteristics. Particularly appealing in this regard, electrophotonic devices capable of coupling light to electron translocation have experienced rapid recent growth and offer significant advantages for diagnostics. In this chapter, we explore three specific promising approaches that combine electronics and photonics: (a) assays based on closed bipolar electrochemistry coupling electron transfer to color or fluorescence (b) sensors based on localized surface plasmon resonances, and (c) emerging nanophotonics approaches, such as those based on zero-mode waveguides and metamaterials.

Authors:
 [1];  [2];  [1];  [1];  [1]
  1. Univ. of Notre Dame, Notre Dame, IN (United States)
  2. Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Publication Date:
Research Org.:
Univ. of Notre Dame, Notre Dame, IN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1494119
Grant/Contract Number:  
FG02-07ER15851
Resource Type:
Accepted Manuscript
Journal Name:
Cold Spring Harbor Perspectives in Medicine
Additional Journal Information:
Journal Volume: 10; Journal Issue: 7; Journal ID: ISSN 2157-1422
Publisher:
Cold Spring Harbor Laboratory Press
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Fu, Kaiyu, Xu, Wei, Hu, Jiayun, Lopez, Arielle, and Bohn, Paul W. Microscale and Nanoscale Electrophotonic Diagnostic Devices. United States: N. p., 2018. Web. doi:10.1101/cshperspect.a034249.
Fu, Kaiyu, Xu, Wei, Hu, Jiayun, Lopez, Arielle, & Bohn, Paul W. Microscale and Nanoscale Electrophotonic Diagnostic Devices. United States. doi:10.1101/cshperspect.a034249.
Fu, Kaiyu, Xu, Wei, Hu, Jiayun, Lopez, Arielle, and Bohn, Paul W. Mon . "Microscale and Nanoscale Electrophotonic Diagnostic Devices". United States. doi:10.1101/cshperspect.a034249. https://www.osti.gov/servlets/purl/1494119.
@article{osti_1494119,
title = {Microscale and Nanoscale Electrophotonic Diagnostic Devices},
author = {Fu, Kaiyu and Xu, Wei and Hu, Jiayun and Lopez, Arielle and Bohn, Paul W.},
abstractNote = {Detecting and identifying infectious agents and potential pathogens in complex environments and characterizing their mode of action is a critical need. Traditional diagnostics have targeted a single characteristic, e.g. spectral response, surface receptor, mass, intrinsic conductivity, etc. However, advances in detection technologies have identified emerging approaches in which multiple modes of action are combined to obtain enhanced performance characteristics. Particularly appealing in this regard, electrophotonic devices capable of coupling light to electron translocation have experienced rapid recent growth and offer significant advantages for diagnostics. In this chapter, we explore three specific promising approaches that combine electronics and photonics: (a) assays based on closed bipolar electrochemistry coupling electron transfer to color or fluorescence (b) sensors based on localized surface plasmon resonances, and (c) emerging nanophotonics approaches, such as those based on zero-mode waveguides and metamaterials.},
doi = {10.1101/cshperspect.a034249},
journal = {Cold Spring Harbor Perspectives in Medicine},
number = 7,
volume = 10,
place = {United States},
year = {2018},
month = {8}
}

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