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Title: Molecular Targeted NIR-II Probe for Image-Guided Brain Tumor Surgery

Journal Article · · Bioconjugate Chemistry
ORCiD logo [1];  [2];  [3];  [3];  [3];  [4];  [5];  [2]; ORCiD logo [3]
  1. Molecular Imaging Program at Stanford (MIPS), Bio-X Program, and Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, Stanford, California, 94305-5344, United States, Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Department of Biomedical Sciences, Rigshospitalet and University of Copenhagen, 2200 Copenhagen N, Denmark
  2. Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Department of Biomedical Sciences, Rigshospitalet and University of Copenhagen, 2200 Copenhagen N, Denmark
  3. Molecular Imaging Program at Stanford (MIPS), Bio-X Program, and Department of Radiology, Canary Center at Stanford for Cancer Early Detection, Stanford University, Stanford, California, 94305-5344, United States
  4. Finsen Laboratory, Rigshospitalet, 2200 Copenhagen N, Denmark, Biotech Research and Innovation Centre (BRIC), University of Copenhagen, 2200 Copenhagen N, Denmark
  5. Department of Plastic Surgery, Breast Surgery and Burns Treatment, Rigshospitalet and University of Copenhagen, 2100 Copenhagen Ø, Denmark
+ Show Author Affiliations

Not Available

Research Organization:
Stanford Univ., CA (United States); Univ. of Copenhagen (Denmark)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER); USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
Grant/Contract Number:
SC0008397
OSTI ID:
1493382
Journal Information:
Bioconjugate Chemistry, Journal Name: Bioconjugate Chemistry Journal Issue: 11 Vol. 29; ISSN 1043-1802
Publisher:
American Chemical SocietyCopyright Statement
Country of Publication:
United States
Language:
English

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Use of methylene blue and near-infrared fluorescence in thyroid and parathyroid surgery journal December 2017
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Estimating progression-free survival in patients with glioblastoma using routinely collected data journal September 2017
The Value of Extent of Resection of Glioblastomas: Clinical Evidence and Current Approach journal December 2014
A novel plectin/integrin-targeted bispecific molecular probe for magnetic resonance/near-infrared imaging of pancreatic cancer journal November 2018
A tantalum oxide-based core/shell nanoparticle for triple-modality image-guided chemo-thermal synergetic therapy of esophageal carcinoma journal July 2017
Preoperative Examination and Intraoperative Identification of Hepatocellular Carcinoma Using a Targeted Bimodal Imaging Probe journal March 2018
Dynamics of Urokinase Receptor Interaction with Peptide Antagonists Studied by Amide Hydrogen Exchange and Mass Spectrometry † journal November 2004
A high quantum yield molecule-protein complex fluorophore for near-infrared II imaging journal May 2017
Multifunctional in vivo vascular imaging using near-infrared II fluorescence journal November 2012
A small-molecule dye for NIR-II imaging journal November 2015
Intraoperative vascular DIVA surgery reveals angiogenic hotspots in tumor zones of malignant gliomas journal January 2015
Targeted polypyrrole nanoparticles for the identification and treatment of hepatocellular carcinoma journal January 2018
Conformational Regulation of Urokinase Receptor Function journal September 2011
Intraoperative Detection of Malignant Gliomas by 5-Aminolevulinic Acid-induced Porphyrin Fluorescence journal March 1998
Urokinase‐type plasminogen activator receptor ( uPAR ) as a promising new imaging target: potential clinical applications journal April 2013
Extent of Resection and Survival in Glioblastoma Multiforme journal March 2008
Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105 journal February 2016
uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model journal December 2016
The Urokinase Receptor as a Potential Target in Cancer Therapy journal July 2004
Evaluation of Intraoperative Brain Shift Using an Ultrasound-Linked Navigation System for Brain Tumor Surgery journal January 2010
Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma journal October 2015
Safety, Dosimetry, and Tumor Detection Ability of 68 Ga-NOTA-AE105: First-in-Human Study of a Novel Radioligand for uPAR PET Imaging journal September 2016
Brain shift during bur hole–based procedures using interventional MRI: Clinical article journal July 2014
Study of the biodistribution of fluorescein in glioma-infiltrated mouse brain and histopathological correlation of intraoperative findings in high-grade gliomas resected under fluorescein fluorescence guidance journal June 2015
First-in-human uPAR PET: Imaging of Cancer Aggressiveness journal January 2015

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