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Title: Biokinetics of 238Pu oxides: Inferences from bioassay data

Abstract

The bioassay data collected from several workers involved in 238Pu inhalation incidents have been analyzed using the most recent biokinetic models described in Occupational Intakes of Radionuclides (OIR) series of publications. Although all exposures were thought to be to 238Pu oxides, the observed urinary excretion patterns differed in different inhalation incidents. The urinary excretion from individuals involved in one of the incidents increased steadily with time peaking around 2-3 years before decreasing. This pattern is described in Part 4 of the OIR series using the ‘238PuO2, ceramic’ model. This non-monotonic behavior, explained as being due to fragmentation and dissolution, was not specific to the incident, but was also observed in other incidents. The urinary excretion data collected from individuals involved in another incident showed dissolution behavior between Type M and Type S. Finally, the bioassay data from yet another incident showed a pattern that appears to represent behavior more insoluble than Type S, which is possibly a result of self-heating due to the decay heat from 238Pu. The urinary excretion patterns and the corresponding dose coefficients have been calculated and compared.

Authors:
 [1];  [1];  [1];  [1];  [1]
  1. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1489966
Report Number(s):
LA-UR-18-29587
Journal ID: ISSN 0952-4746
Grant/Contract Number:  
89233218CNA000001
Resource Type:
Accepted Manuscript
Journal Name:
Journal of Radiological Protection
Additional Journal Information:
Journal Volume: 39; Journal Issue: 1; Journal ID: ISSN 0952-4746
Publisher:
IOP Publishing
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; biokinetics; dosimetry, internal; 238Pu; inhalation

Citation Formats

Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A., Dumit, Sara, and Waters, Tom L. Biokinetics of 238Pu oxides: Inferences from bioassay data. United States: N. p., 2019. Web. doi:10.1088/1361-6498/aaf653.
Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A., Dumit, Sara, & Waters, Tom L. Biokinetics of 238Pu oxides: Inferences from bioassay data. United States. doi:10.1088/1361-6498/aaf653.
Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A., Dumit, Sara, and Waters, Tom L. Tue . "Biokinetics of 238Pu oxides: Inferences from bioassay data". United States. doi:10.1088/1361-6498/aaf653. https://www.osti.gov/servlets/purl/1489966.
@article{osti_1489966,
title = {Biokinetics of 238Pu oxides: Inferences from bioassay data},
author = {Poudel, Deepesh and Bertelli, Luiz and Klumpp, John A. and Dumit, Sara and Waters, Tom L.},
abstractNote = {The bioassay data collected from several workers involved in 238Pu inhalation incidents have been analyzed using the most recent biokinetic models described in Occupational Intakes of Radionuclides (OIR) series of publications. Although all exposures were thought to be to 238Pu oxides, the observed urinary excretion patterns differed in different inhalation incidents. The urinary excretion from individuals involved in one of the incidents increased steadily with time peaking around 2-3 years before decreasing. This pattern is described in Part 4 of the OIR series using the ‘238PuO2, ceramic’ model. This non-monotonic behavior, explained as being due to fragmentation and dissolution, was not specific to the incident, but was also observed in other incidents. The urinary excretion data collected from individuals involved in another incident showed dissolution behavior between Type M and Type S. Finally, the bioassay data from yet another incident showed a pattern that appears to represent behavior more insoluble than Type S, which is possibly a result of self-heating due to the decay heat from 238Pu. The urinary excretion patterns and the corresponding dose coefficients have been calculated and compared.},
doi = {10.1088/1361-6498/aaf653},
journal = {Journal of Radiological Protection},
number = 1,
volume = 39,
place = {United States},
year = {2019},
month = {2}
}

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