Biokinetics of 238Pu oxides: Inferences from bioassay data
Abstract
The bioassay data collected from several workers involved in 238Pu inhalation incidents have been analyzed using the most recent biokinetic models described in Occupational Intakes of Radionuclides (OIR) series of publications. Although all exposures were thought to be to 238Pu oxides, the observed urinary excretion patterns differed in different inhalation incidents. The urinary excretion from individuals involved in one of the incidents increased steadily with time peaking around 2-3 years before decreasing. This pattern is described in Part 4 of the OIR series using the ‘238PuO2, ceramic’ model. This non-monotonic behavior, explained as being due to fragmentation and dissolution, was not specific to the incident, but was also observed in other incidents. The urinary excretion data collected from individuals involved in another incident showed dissolution behavior between Type M and Type S. Finally, the bioassay data from yet another incident showed a pattern that appears to represent behavior more insoluble than Type S, which is possibly a result of self-heating due to the decay heat from 238Pu. The urinary excretion patterns and the corresponding dose coefficients have been calculated and compared.
- Authors:
-
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Publication Date:
- Research Org.:
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1489966
- Report Number(s):
- LA-UR-18-29587
Journal ID: ISSN 0952-4746
- Grant/Contract Number:
- 89233218CNA000001
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of Radiological Protection
- Additional Journal Information:
- Journal Volume: 39; Journal Issue: 1; Journal ID: ISSN 0952-4746
- Publisher:
- IOP Publishing
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 61 RADIATION PROTECTION AND DOSIMETRY; biokinetics; dosimetry, internal; 238Pu; inhalation
Citation Formats
Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A., Dumit, Sara, and Waters, Tom L. Biokinetics of 238Pu oxides: Inferences from bioassay data. United States: N. p., 2019.
Web. doi:10.1088/1361-6498/aaf653.
Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A., Dumit, Sara, & Waters, Tom L. Biokinetics of 238Pu oxides: Inferences from bioassay data. United States. https://doi.org/10.1088/1361-6498/aaf653
Poudel, Deepesh, Bertelli, Luiz, Klumpp, John A., Dumit, Sara, and Waters, Tom L. Tue .
"Biokinetics of 238Pu oxides: Inferences from bioassay data". United States. https://doi.org/10.1088/1361-6498/aaf653. https://www.osti.gov/servlets/purl/1489966.
@article{osti_1489966,
title = {Biokinetics of 238Pu oxides: Inferences from bioassay data},
author = {Poudel, Deepesh and Bertelli, Luiz and Klumpp, John A. and Dumit, Sara and Waters, Tom L.},
abstractNote = {The bioassay data collected from several workers involved in 238Pu inhalation incidents have been analyzed using the most recent biokinetic models described in Occupational Intakes of Radionuclides (OIR) series of publications. Although all exposures were thought to be to 238Pu oxides, the observed urinary excretion patterns differed in different inhalation incidents. The urinary excretion from individuals involved in one of the incidents increased steadily with time peaking around 2-3 years before decreasing. This pattern is described in Part 4 of the OIR series using the ‘238PuO2, ceramic’ model. This non-monotonic behavior, explained as being due to fragmentation and dissolution, was not specific to the incident, but was also observed in other incidents. The urinary excretion data collected from individuals involved in another incident showed dissolution behavior between Type M and Type S. Finally, the bioassay data from yet another incident showed a pattern that appears to represent behavior more insoluble than Type S, which is possibly a result of self-heating due to the decay heat from 238Pu. The urinary excretion patterns and the corresponding dose coefficients have been calculated and compared.},
doi = {10.1088/1361-6498/aaf653},
journal = {Journal of Radiological Protection},
number = 1,
volume = 39,
place = {United States},
year = {Tue Feb 05 00:00:00 EST 2019},
month = {Tue Feb 05 00:00:00 EST 2019}
}
Web of Science
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