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Title: A morphological, enzymatic and metabolic approach to elucidate apoptotic-like cell death in fungi exposed to h- and α-molybdenum trioxide nanoparticles

Abstract

The present study compares for the first time the effects of h-MoO 3 and α-MoO 3 against two fungal strains: Aspergillus niger and Aspergillus flavus .

Authors:
ORCiD logo [1];  [2];  [3];  [2];  [1]; ORCiD logo [2]
  1. Facoltà di Bioscenze e Tecnologie Agroalimentari ed ambientali, Università degli Studi di Teramo, 64100 Teramo, Italy
  2. Department of Civil and Environmental Engineering, University of Houston, Houston, USA
  3. Departament of Microbiology, University of Sao Paulo, Sao Paulo, Brazil
Publication Date:
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER)
OSTI Identifier:
1481033
Grant/Contract Number:  
AC52-06NA25396
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
Nanoscale
Additional Journal Information:
Journal Name: Nanoscale Journal Volume: 10 Journal Issue: 44; Journal ID: ISSN 2040-3364
Publisher:
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Chaves-Lopez, Clemencia, Nguyen, Hang N., Oliveira, Rodrigo C., Nadres, Enrico T., Paparella, Antonello, and Rodrigues, Debora F. A morphological, enzymatic and metabolic approach to elucidate apoptotic-like cell death in fungi exposed to h- and α-molybdenum trioxide nanoparticles. United Kingdom: N. p., 2018. Web. doi:10.1039/C8NR06470A.
Chaves-Lopez, Clemencia, Nguyen, Hang N., Oliveira, Rodrigo C., Nadres, Enrico T., Paparella, Antonello, & Rodrigues, Debora F. A morphological, enzymatic and metabolic approach to elucidate apoptotic-like cell death in fungi exposed to h- and α-molybdenum trioxide nanoparticles. United Kingdom. https://doi.org/10.1039/C8NR06470A
Chaves-Lopez, Clemencia, Nguyen, Hang N., Oliveira, Rodrigo C., Nadres, Enrico T., Paparella, Antonello, and Rodrigues, Debora F. Thu . "A morphological, enzymatic and metabolic approach to elucidate apoptotic-like cell death in fungi exposed to h- and α-molybdenum trioxide nanoparticles". United Kingdom. https://doi.org/10.1039/C8NR06470A.
@article{osti_1481033,
title = {A morphological, enzymatic and metabolic approach to elucidate apoptotic-like cell death in fungi exposed to h- and α-molybdenum trioxide nanoparticles},
author = {Chaves-Lopez, Clemencia and Nguyen, Hang N. and Oliveira, Rodrigo C. and Nadres, Enrico T. and Paparella, Antonello and Rodrigues, Debora F.},
abstractNote = {The present study compares for the first time the effects of h-MoO 3 and α-MoO 3 against two fungal strains: Aspergillus niger and Aspergillus flavus .},
doi = {10.1039/C8NR06470A},
journal = {Nanoscale},
number = 44,
volume = 10,
place = {United Kingdom},
year = {2018},
month = {11}
}

Works referenced in this record:

Aqueous supercapacitors of high energy density based on MoO3 nanoplates as anode material
journal, January 2011

  • Tang, Wei; Liu, Lili; Tian, Shu
  • Chemical Communications, Vol. 47, Issue 36
  • DOI: 10.1039/c1cc13474d

On the safety of Aspergillus niger - a review
journal, January 2002

  • Schuster, E.; Dunn-Coleman, N.; Frisvad, J.
  • Applied Microbiology and Biotechnology, Vol. 59, Issue 4-5, p. 426-435
  • DOI: 10.1007/s00253-002-1032-6

Hydrothermal Synthesis of α-MoO 3 Nanorods via Acidification of Ammonium Heptamolybdate Tetrahydrate
journal, November 2002

  • Lou, Xiong Wen; Zeng, Hua Chun
  • Chemistry of Materials, Vol. 14, Issue 11
  • DOI: 10.1021/cm0206237

Density functional studies of the electronic structure and adsorption at molybdenum oxide surfaces
journal, May 1999


Digestive physiology comparisons of aquatic invertebrates in the Upper Mississippi River Basin
journal, January 2016


Volatile profiles of fungi – Chemotyping of species and ecological functions
journal, May 2013


Engineering of a fungal β-galactosidase to remove product inhibition by galactose
journal, May 2010

  • Hu, Xuejun; Robin, Sylvain; O’Connell, Shane
  • Applied Microbiology and Biotechnology, Vol. 87, Issue 5
  • DOI: 10.1007/s00253-010-2662-8

Comparative efficiency of acid phosphatase originated from plant and fungal sources
journal, June 2001


Profiles of digestive enzymes of two competing planktivores, silver carp and gizzard shad, differ
journal, February 2018

  • Amberg, Jon J.; Jensen, Nathan R.; Erickson, Richard A.
  • Ichthyological Research, Vol. 65, Issue 2
  • DOI: 10.1007/s10228-018-0615-x

De novo production of (+)-aristolochene by sporulated surface cultures of Penicillium roqueforti
journal, March 2002


Separation and identification of hydrocarbons and other volatile compounds from cultures of Aspergillus niger by GC–MS using two different capillary columns and solvents
journal, May 2015

  • Siddiquee, Shafiquzzaman; Azad, Sujjat Al; Abu Bakar, Fatimah
  • Journal of Saudi Chemical Society, Vol. 19, Issue 3
  • DOI: 10.1016/j.jscs.2012.02.007

Aspergillus flavus hydrolases: their roles in pathogenesis and substrate utilization
journal, October 2007

  • Mellon, Jay E.; Cotty, Peter J.; Dowd, Michael K.
  • Applied Microbiology and Biotechnology, Vol. 77, Issue 3
  • DOI: 10.1007/s00253-007-1201-8

Effects of Conventional and High-Oleic Peanut Medium on Extracellular Enzyme Production and Mycelial Growth of Aspergillus Flavus : EFFECTS OF PEANUT CULTIVARS ON
journal, January 2016

  • Zorzete, Patricia; Oliveira, Rodrigo Cardoso; Corrêa, Benedito
  • Journal of Food Safety, Vol. 36, Issue 4
  • DOI: 10.1111/jfs.12262

Fungal extracellular enzyme activity associated with the breakdown of plant cell biomass
journal, November 1989


Investigation of acid phosphatase variants for the synthesis of phosphate monoesters: Engineered Phosphatases
journal, July 2017

  • Tasnádi, Gábor; Zechner, Michaela; Hall, Mélanie
  • Biotechnology and Bioengineering, Vol. 114, Issue 10
  • DOI: 10.1002/bit.26352

Hydrothermally Synthesized h-MoO 3 and α-MoO 3 Nanocrystals: New Findings on Crystal-Structure-Dependent Charge Transport
journal, March 2016

  • Chithambararaj, A.; Rajeswari Yogamalar, N.; Bose, A. Chandra
  • Crystal Growth & Design, Vol. 16, Issue 4
  • DOI: 10.1021/acs.cgd.5b01571

Antimicrobial activity of transition metal acid MoO3 prevents microbial growth on material surfaces
journal, January 2012

  • Zollfrank, Cordt; Gutbrod, Kai; Wechsler, Peter
  • Materials Science and Engineering: C, Vol. 32, Issue 1
  • DOI: 10.1016/j.msec.2011.09.010

The Tetrazolium Dyes MTS and XTT Provide New Quantitative Assays for Superoxide and Superoxide Dismutase
journal, January 1997


Functionalization of reduced graphene oxide with polysulfone brushes enhance antibacterial properties and reduce human cytotoxicity
journal, January 2017


Flower-like hierarchical h-MoO3: new findings of efficient visible light driven nano photocatalyst for methylene blue degradation
journal, January 2013

  • Chithambararaj, A.; Sanjini, N. S.; Bose, A. Chandra
  • Catalysis Science & Technology, Vol. 3, Issue 5
  • DOI: 10.1039/c3cy20764a

Synthesis of h- and α -MoO 3 by Refluxing and Calcination Combination: Phase and Morphology Transformation, Photocatalysis, and Photosensitization
journal, January 2013

  • Wongkrua, Pannipa; Thongtem, Titipun; Thongtem, Somchai
  • Journal of Nanomaterials, Vol. 2013
  • DOI: 10.1155/2013/702679

Improved enzyme production by co-cultivation of Aspergillus niger and Aspergillus oryzae and with other fungi
journal, January 2011

  • Hu, H. L.; van den Brink, J.; Gruben, B. S.
  • International Biodeterioration & Biodegradation, Vol. 65, Issue 1
  • DOI: 10.1016/j.ibiod.2010.11.008

Single-Crystalline Molybdenum Trioxide Nanoribbons: Photocatalytic, Photoconductive, and Electrochemical Properties
journal, February 2009

  • Cheng, Liang; Shao, Mingwang; Wang, Xiuhua
  • Chemistry - A European Journal, Vol. 15, Issue 10
  • DOI: 10.1002/chem.200802182

Nanostructured molybdenum oxide-based antibacterial paint: effective growth inhibition of various pathogenic bacteria
journal, July 2014


Cell wall structure and biogenesis in Aspergillus species
journal, February 2016


Ultrasonic synthesis of MoO3 nanorods and their gas sensing properties
journal, November 2012


Impact of Photocatalysis on Fungal Cells: Depiction of Cellular and Molecular Effects on Saccharomyces cerevisiae
journal, September 2014

  • Thabet, Sana; Simonet, France; Lemaire, Marc
  • Applied and Environmental Microbiology, Vol. 80, Issue 24
  • DOI: 10.1128/AEM.02416-14

Aspergillus flavus: human pathogen, allergen and mycotoxin producer
journal, June 2007


Apoptosis in yeast: triggers, pathways, subroutines
journal, January 2010

  • Carmona-Gutierrez, D.; Eisenberg, T.; Büttner, S.
  • Cell Death & Differentiation, Vol. 17, Issue 5
  • DOI: 10.1038/cdd.2009.219

Apoptotic Cells, at All Stages of the Death Process, Trigger Characteristic Signaling Events That Are Divergent from and Dominant over Those Triggered by Necrotic Cells
journal, December 2005

  • Patel, Vimal A.; Longacre, Angelika; Hsiao, Kevin
  • Journal of Biological Chemistry, Vol. 281, Issue 8
  • DOI: 10.1074/jbc.M508342200

The Activity and Characterization of acid Phosphatases in Endomycorrhizal Fungi of the Ericaceae
journal, October 1986


Nigella damascena L. Essential Oil—A Valuable Source of β-Elemene for Antimicrobial Testing
journal, January 2018


Biological and environmental interactions of emerging two-dimensional nanomaterials
journal, January 2016

  • Wang, Zhongying; Zhu, Wenpeng; Qiu, Yang
  • Chemical Society Reviews, Vol. 45, Issue 6
  • DOI: 10.1039/C5CS00914F

Aspergillus -Associated Airway Disease, Inflammation, and the Innate Immune Response
journal, January 2013

  • Chotirmall, Sanjay H.; Al-Alawi, Mazen; Mirkovic, Bojana
  • BioMed Research International, Vol. 2013
  • DOI: 10.1155/2013/723129

Enzymatic Characterization of Corynespora cassiicola Isolates Using the API-ZYM ® System
journal, November 2012

  • de Oliveira, Rodrigo Cardoso; de Oliveira, Ricardo Ribeiro; de Marchi Bordon, Caroline
  • Journal of Phytopathology, Vol. 161, Issue 3
  • DOI: 10.1111/jph.12043

Fungal secondary metabolism — from biochemistry to genomics
journal, December 2005

  • Keller, Nancy P.; Turner, Geoffrey; Bennett, Joan W.
  • Nature Reviews Microbiology, Vol. 3, Issue 12, p. 937-947
  • DOI: 10.1038/nrmicro1286

Smelling the difference: Transcriptome, proteome and volatilome changes after mating
journal, March 2018


Investigation on structural, thermal, optical and sensing properties of meta-stable hexagonal MoO 3 nanocrystals of one dimensional structure
journal, January 2011

  • Chithambararaj, Angamuthuraj; Bose, Arumugam Chandra
  • Beilstein Journal of Nanotechnology, Vol. 2
  • DOI: 10.3762/bjnano.2.62

Water availability affects extracellular hydrolytic enzyme production by Aspergillus flavus and Aspergillus parasiticus
journal, August 2009


α-MoO 3 /polyaniline composite for effective scavenging of Rhodamine B, Congo red and textile dye effluent
journal, January 2016

  • Dhanavel, S.; Nivethaa, E. A. K.; Dhanapal, K.
  • RSC Advances, Vol. 6, Issue 34
  • DOI: 10.1039/C6RA02576E

Enzymic analysis of microbial pattern and process
journal, January 1994

  • Sinsabaugh, R. S.
  • Biology and Fertility of Soils, Vol. 17, Issue 1
  • DOI: 10.1007/BF00418675

Chitinase but N-acetyl- β -D-glucosaminidase production correlates to the biomass decline in Penicillium and Aspergillus species
journal, June 2014

  • Pusztahelyi, Tünde; Pócsi, István
  • Acta Microbiologica et Immunologica Hungarica, Vol. 61, Issue 2
  • DOI: 10.1556/AMicr.61.2014.2.4

Multidrug Resistance in Fungi
journal, September 2007

  • Gulshan, Kailash; Moye-Rowley, W. Scott
  • Eukaryotic Cell, Vol. 6, Issue 11
  • DOI: 10.1128/EC.00254-07

Phytotoxic and Fungitoxic Activities of the Essential Oil of Kenaf ( Hibiscus cannabinus L.) Leaves and Its Composition
journal, August 2001

  • Kobaisy, Mozaina; Tellez, Mario R.; Webber, Charles L.
  • Journal of Agricultural and Food Chemistry, Vol. 49, Issue 8
  • DOI: 10.1021/jf0101455

New function of molybdenum trioxide nanoplates: Toxicity towards pathogenic bacteria through membrane stress
journal, December 2013

  • Krishnamoorthy, Karthikeyan; Veerapandian, Murugan; Yun, Kyusik
  • Colloids and Surfaces B: Biointerfaces, Vol. 112
  • DOI: 10.1016/j.colsurfb.2013.08.026

Fungal Beta-Glucosidases: A Bottleneck in Industrial Use of Lignocellulosic Materials
journal, September 2013

  • Sørensen, Annette; Lübeck, Mette; Lübeck, Peter
  • Biomolecules, Vol. 3, Issue 4
  • DOI: 10.3390/biom3030612

Chemically Grown MoO3 Nanorods for Antibacterial Activity Study
journal, January 2015


Chemotyping the temporal volatile organic compounds of an invasive fungus to the United States, Raffaelea lauricola
journal, March 2017


Influence of environmental factors on tenuazonic acid production by Epicoccum sorghinum: An integrative approach of field and laboratory conditions
journal, November 2018


Soft chemical synthesis of a high-pressure phase of molybdenum trioxide: MoO3-II
journal, October 1995


Shedding light on Aspergillus niger volatile exometabolome
journal, June 2016

  • Costa, Carina Pedrosa; Gonçalves Silva, Diogo; Rudnitskaya, Alisa
  • Scientific Reports, Vol. 6, Issue 1
  • DOI: 10.1038/srep27441

Designing polymeric adhesives for antimicrobial materials: poly(ethylene imine) polymer, graphene, graphene oxide and molybdenum trioxide – a biomimetic approach
journal, January 2017

  • Nguyen, Hang N.; Nadres, Enrico T.; Alamani, Bryan G.
  • Journal of Materials Chemistry B, Vol. 5, Issue 32
  • DOI: 10.1039/C7TB00722A

Effects ofCymbopogon citratus L. essential oil on the growth, morphogenesis and aflatoxin production ofAspergillus flavus ML2-strain
journal, February 2007

  • Helal, G. A.; Sarhan, M. M.; Abu Shahla, A. N. K.
  • Journal of Basic Microbiology, Vol. 47, Issue 1
  • DOI: 10.1002/jobm.200610137

Raman studies of hexagonal MoO3 at high pressure
journal, March 2011

  • Zhang, C. C.; Zheng, L.; Zhang, Z. M.
  • physica status solidi (b), Vol. 248, Issue 5
  • DOI: 10.1002/pssb.201000633

Identification of volatile markers for indoor fungal growth and chemotaxonomic classification of Aspergillus species
journal, September 2012


Microbial volatile organic compounds as indicators of fungi. Can an electronic nose detect fungi in indoor environments?
journal, June 2005


Antibacterial Activity of Graphite, Graphite Oxide, Graphene Oxide, and Reduced Graphene Oxide: Membrane and Oxidative Stress
journal, August 2011

  • Liu, Shaobin; Zeng, Tingying Helen; Hofmann, Mario
  • ACS Nano, Vol. 5, Issue 9
  • DOI: 10.1021/nn202451x

Apoptosis pathways in fungal growth, development and ageing
journal, June 2008


Hydrothermal synthesis of hexagonal and orthorhombic MoO3 nanoparticles
journal, August 2011


Aspergillus niger: an unusual cause of invasive pulmonary aspergillosis
journal, March 2010

  • Person, A. K.; Chudgar, S. M.; Norton, B. L.
  • Journal of Medical Microbiology, Vol. 59, Issue 7
  • DOI: 10.1099/jmm.0.018309-0

Hydrolysis of phosphate monoesters: a biological problem with multiple chemical solutions
journal, March 1992


Molecular mechanisms of late apoptotic/necrotic cell clearance
journal, December 2009

  • Poon, I. K. H.; Hulett, M. D.; Parish, C. R.
  • Cell Death & Differentiation, Vol. 17, Issue 3
  • DOI: 10.1038/cdd.2009.195

Preparation of h-MoO3 and α-MoO3 nanocrystals: comparative study on photocatalytic degradation of methylene blue under visible light irradiation
journal, January 2013

  • Chithambararaj, A.; Sanjini, N. S.; Velmathi, S.
  • Physical Chemistry Chemical Physics, Vol. 15, Issue 35
  • DOI: 10.1039/c3cp51796a

Growth and metabolites production by Penicillium brevicompactum in yoghurt
journal, October 2008


Production of Cellulase/β-Glucosidase by the Mixed Fungi Culture of <I> Trichoderma reesei </I>and <I>Aspergillus phoenicis </I>on Dairy Manure
journal, January 2005

  • Wen, Zhiyou; Liao, Wei; Chen, Shulin
  • Applied Biochemistry and Biotechnology, Vol. 121, Issue 1-3
  • DOI: 10.1385/ABAB:121:1-3:0093

Chemical composition and antifungal properties of the essential oil and various extracts of Mikania scandens (L.) Willd
journal, May 2017


Tissue sulfhydryl groups
journal, May 1959


Characterization and properties of acid phosphatases with phytase activity produced by Aspergillus caespitosus
journal, October 2004

  • Guimarães, Luis Henrique S.; Terenzi, Héctor F.; Jorge, João A.
  • Biotechnology and Applied Biochemistry, Vol. 40, Issue 2
  • DOI: 10.1042/BA20030208

Hydrothermal synthesis and electrochemical properties of α-MoO3 nanobelts used as cathode materials for Li-ion batteries
journal, January 2012


Volatile fungal metabolites and their relation to the spoilage of agricultural commodities
journal, November 1998


Diversity of food-borne Bacillus volatile compounds and influence on fungal growth
journal, June 2015

  • Chaves-López, C.; Serio, A.; Gianotti, A.
  • Journal of Applied Microbiology, Vol. 119, Issue 2
  • DOI: 10.1111/jam.12847