Title: Complete Genome Sequences of Historic Clostridioides difficile Food-Dwelling Ribotype 078 Strains in Canada Identical to That of the Historic Human Clinical Strain M120 in the United Kingdom

Journal Article · · Microbiology Resource Announcements
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  1. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  2. Case Western Reserve Univ., Cleveland, OH (United States)
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Here, Clostridioides (Clostridium) difficile is a spore-forming anaerobic bacterium that causes severe intestinal diseases in humans. Here, we report the complete genome sequence of the first C. difficile foodborne type strain (PCR ribotype 078) isolated from food animals in Canada in 2004, which has 100% similarity to the genome sequence of the historic human clinical strain M120.

Research Organization:
Los Alamos National Laboratory (LANL)
Sponsoring Organization:
LDRD; USDOE
Grant/Contract Number:
AC52-06NA25396
OSTI ID:
1480026
Report Number(s):
LA-UR-18-22191
Journal Information:
Microbiology Resource Announcements, Journal Name: Microbiology Resource Announcements Journal Issue: 12 Vol. 7; ISSN 2576-098X
Country of Publication:
United States
Language:
English

References (17)

Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe journal September 2005
Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe journal September 2005
Risk factors for Clostridium difficile infection in the community: a case-control study in patients in general practice, Denmark, 2009–2011 journal September 2013
Clostridium difficile in foods and animals: history and measures to reduce exposure journal January 2013
Food Indwelling Clostridium difficile in Naturally Contaminated Household Meals: Data for Expanded Risk Mathematical Predictions journal February 2017
Risk factors for Clostridium difficile infection in the community: a case-control study in patients in general practice, Denmark, 2009–2011 journal September 2013
Clostridium difficile in foods and animals: history and measures to reduce exposure journal January 2013
An Epidemic, Toxin Gene–Variant Strain of Clostridium difficile journal December 2005
Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing journal September 2013
An Epidemic, Toxin Gene–Variant Strain of Clostridium difficile journal December 2005
Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing journal September 2013
Evolutionary dynamics of Clostridium difficile over short and long time scales journal April 2010
Prokka: rapid prokaryotic genome annotation journal March 2014
Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform journal November 2016
Draft Genome Sequence of Comamonas aquatilis Strain LK (= CSUR P6418 = CECT 9772), Isolated from the Planarian Schmidtea mediterranea journal February 2021
Subboiling Moist Heat Favors the Selection of Enteric Pathogen Clostridium difficile PCR Ribotype 078 Spores in Food journal January 2016
Clostridium difficile PCR Ribotypes in Calves, Canada journal January 2006

Cited By (1)

Complete Genome Sequence of a Parabacteroides distasonis Strain (CavFT hAR46) Isolated from a Gut Wall-Cavitating Microlesion in a Patient with Severe Crohn’s Disease journal September 2019

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59 BASIC BIOLOGICAL SCIENCES
Whole genome sequencing
C.difficile
food production system