New Structural Biology Facilities at NSLS-II

Berman, Lonny

doi:10.1080/08940886.2018.1506245

Title: New Structural Biology Facilities at NSLS-II

Abstract

The National Synchrotron Light Source II (NSLS-II), a Department of Energy (DOE) Office of Science User Facility located at Brookhaven National Laboratory offers an advanced suite of beamlines dedicated to structural biology research for investigating problems ranging from the atomic to the cellular scale. The beamlines are now available for general users, while adjacent wet and dry laboratories will become available soon. These beamlines offer X-ray diffraction, scattering, footprinting, spectroscopy, and imaging techniques that capitalize on NSLS-II's brightness.

Authors:

Berman, Lonny ^[1]

Brookhaven National Lab. (BNL), Upton, NY (United States). National Synchrotron Light Source II (NSLS-II)

Publication Date:: 2018-09-25

Research Org.:: Brookhaven National Lab. (BNL), Upton, NY (United States)

Sponsoring Org.:: USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOE Office of Science (SC), Biological and Environmental Research (BER); USDOD; National Institutes of Health (NIH); National Science Foundation (NSF); New York Structural Biology Center (NYSBC), New York City, NY (United States); Stony Brook Univ., NY (United States); Case Western Reserve Univ., Cleveland, OH (United States); Arizona State Univ., Mesa, AZ (United States)

OSTI Identifier:: 1476289

Report Number(s):: BNL-209123-2018-JAAM
Journal ID: ISSN 0894-0886

Grant/Contract Number:: SC0012704

Resource Type:: Accepted Manuscript

Journal Name:: Synchrotron Radiation News

Additional Journal Information:: Journal Volume: 31; Journal Issue: 5; Journal ID: ISSN 0894-0886

Publisher:: Taylor & Francis

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES; 43 PARTICLE ACCELERATORS

Citation Formats


                    Berman, Lonny. New Structural Biology Facilities at NSLS-II.  United States: N. p., 2018. 
Web.  doi:10.1080/08940886.2018.1506245.

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                    Berman, Lonny. New Structural Biology Facilities at NSLS-II.  United States.  https://doi.org/10.1080/08940886.2018.1506245

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                    Berman, Lonny. Tue .  
"New Structural Biology Facilities at NSLS-II".  United States.  https://doi.org/10.1080/08940886.2018.1506245.  https://www.osti.gov/servlets/purl/1476289.

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@article{osti_1476289,

  title        = {New Structural Biology Facilities at NSLS-II},

  author       = {Berman, Lonny},

  abstractNote = {The National Synchrotron Light Source II (NSLS-II), a Department of Energy (DOE) Office of Science User Facility located at Brookhaven National Laboratory offers an advanced suite of beamlines dedicated to structural biology research for investigating problems ranging from the atomic to the cellular scale. The beamlines are now available for general users, while adjacent wet and dry laboratories will become available soon. These beamlines offer X-ray diffraction, scattering, footprinting, spectroscopy, and imaging techniques that capitalize on NSLS-II's brightness.},

  doi          = {10.1080/08940886.2018.1506245},

  journal      = {Synchrotron Radiation News},

  number       = 5,

  volume       = 31,

  place        = {United States},

  year         = {2018},

  month        = {9}

}

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Figure 1: Manipulation of microcrystals for micro-crystallography. (a) Patterned well mount. Inset: A high-resolution image of microwells to show their shape and dimensions. For better visualization, the 2 μm holes are highlighted by white circles. (b) A generic procedure for harvesting and cooling microcrystals. A micropipette is used to aspiratemore »

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