Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E

doi:10.1016/j.virol.2017.07.008

Title: Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E

Full Record
Other Related Research

Authors:: Li, Mei; Wang, Ping; Zheng, Zifeng; Hu, Kai; Zhang, Mudan; Guan, Xinmeng; Fu, Ming; Zhang, Di; Wang, Wei; Xiao, Gengfu; Hu, Qinxue; Liu, Yalan

Publication Date:: 2017-10-01

Sponsoring Org.:: USDOE Office of Electricity Delivery and Energy Reliability (OE), Power Systems Engineering Research and Development (R&D) (OE-10)

OSTI Identifier:: 1475075

Grant/Contract Number:: [2016YFC1200400]

Resource Type:: Published Article

Journal Name:: Virology

Additional Journal Information:: [Journal Name: Virology Journal Volume: 510 Journal Issue: C]; Journal ID: ISSN 0042-6822

Publisher:: Elsevier

Country of Publication:: United States

Language:: English

Citation Formats


                    Li, Mei, Wang, Ping, Zheng, Zifeng, Hu, Kai, Zhang, Mudan, Guan, Xinmeng, Fu, Ming, Zhang, Di, Wang, Wei, Xiao, Gengfu, Hu, Qinxue, and Liu, Yalan. Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E.  United States: N. p., 2017. 
        Web.  doi:10.1016/j.virol.2017.07.008.

Copy to clipboard


                    Li, Mei, Wang, Ping, Zheng, Zifeng, Hu, Kai, Zhang, Mudan, Guan, Xinmeng, Fu, Ming, Zhang, Di, Wang, Wei, Xiao, Gengfu, Hu, Qinxue, & Liu, Yalan. Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E.  United States.  doi:10.1016/j.virol.2017.07.008.

Copy to clipboard


                    Li, Mei, Wang, Ping, Zheng, Zifeng, Hu, Kai, Zhang, Mudan, Guan, Xinmeng, Fu, Ming, Zhang, Di, Wang, Wei, Xiao, Gengfu, Hu, Qinxue, and Liu, Yalan. Sun .  
        "Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E".  United States.  doi:10.1016/j.virol.2017.07.008.

Copy to clipboard


                    
@article{osti_1475075,

  title        = {Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E},

  author       = {Li, Mei and Wang, Ping and Zheng, Zifeng and Hu, Kai and Zhang, Mudan and Guan, Xinmeng and Fu, Ming and Zhang, Di and Wang, Wei and Xiao, Gengfu and Hu, Qinxue and Liu, Yalan},

  abstractNote = {},

  doi          = {10.1016/j.virol.2017.07.008},

  journal      = {Virology},

  number       = [C],

  volume       = [510],

  place        = {United States},

  year         = {2017},

  month        = {10}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Publisher's Version of Record
DOI: 10.1016/j.virol.2017.07.008

Other availability

Search WorldCat to find libraries that may hold this journal

Citation Metrics:

Cited by: 1 work

Citation information provided by
Web of Science

Save / Share:

Export Metadata

Save to My Library

Similar Records in DOE PAGES and OSTI.GOV collections:

Crystal Structure of the Japanese Encephalitis Virus Envelope Protein

Journal Article Luca, Vincent C ; AbiMansour, Jad ; Nelson, Christopher A ; ... - Journal of Virology

Japanese encephalitis virus (JEV) is the leading global cause of viral encephalitis. The JEV envelope protein (E) facilitates cellular attachment and membrane fusion and is the primary target of neutralizing antibodies. We have determined the 2.1-{angstrom} resolution crystal structure of the JEV E ectodomain refolded from bacterial inclusion bodies. The E protein possesses the three domains characteristic of flavivirus envelopes and epitope mapping of neutralizing antibodies onto the structure reveals determinants that correspond to the domain I lateral ridge, fusion loop, domain III lateral ridge, and domain I-II hinge. While monomeric in solution, JEV E assembles as an antiparallel dimermore »« less
DOI: 10.1128/JVI.06072-11
The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome

Journal Article Engel, Amber R., E-mail: engelam@mail.nih.go ; Rumyantsev, Alexander A., E-mail: alexander.rumyantsev@sanofipasteur.co ; Maximova, Olga A., E-mail: maximovao@mail.nih.go ; ... - Virology

Tick-borne encephalitis (TBE) is a severe disease affecting thousands of people throughout Eurasia. Despite the use of formalin-inactivated vaccines in endemic areas, an increasing incidence of TBE emphasizes the need for an alternative vaccine that will induce a more durable immunity against TBE virus (TBEV). The chimeric attenuated virus vaccine candidate containing the structural protein genes of TBEV on a dengue virus genetic background (TBEV/DEN4) retains a high level of neurovirulence in both mice and monkeys. Therefore, attenuating mutations were introduced into the envelope (E{sub 315}) and NS5 (NS5{sub 654,655}) proteins, and into the 3' non-coding region ({Delta}30) of TBEV/DEN4.more »« less
DOI: 10.1016/j.virol.2010.06.014
Mutation analysis of the fusion domain region of St. Louis encephalitis virus envelope protein

Journal Article Trainor, Nicole B ; Crill, Wayne D ; Roberson, Jill A ; ... - Virology

The immune response to flavivirus infections produces both species-specific and flavivirus cross-reactive antibodies. The presence of cross-reactive antibodies complicates serodiagnosis of flavivirus infections, especially secondary infections caused by a heterologous virus. A successful public health response to the growing global threat posed by flaviviruses necessitates the development of virus-specific diagnostic antigens. The flavivirus envelope (E) glycoprotein is the principle antigen stimulating protective immunity during infection. Using recombinant St. Louis encephalitis virus-like particles (VLPs), we have identified amino acid residues involved in flavivirus cross-reactive epitope determinants. Most significant among the residues studied are three highly conserved amino acids in the fusionmore »« less
DOI: 10.1016/j.virol.2006.10.033
Experimental evidence that RNA recombination occurs in the Japanese encephalitis virus

Journal Article Chuang, C -K ; Chen, W.-J., E-mail: wjchen@mail.cgu.edu.t ; Department of Public Health and Parasitology, Chang Gung University, Kwei-San, Tao-Yuan 33332, Taiwan - Virology

Due to the lack of a proofreading function and error-repairing ability of genomic RNA, accumulated mutations are known to be a force driving viral evolution in the genus Flavivirus, including the Japanese encephalitis (JE) virus. Based on sequencing data, RNA recombination was recently postulated to be another factor associated with genomic variations in these viruses. We herein provide experimental evidence to demonstrate the occurrence of RNA recombination in the JE virus using two local pure clones (T1P1-S1 and CJN-S1) respectively derived from the local strains, T1P1 and CJN. Based on results from a restriction fragment length polymorphism (RFLP) assay onmore »« less
DOI: 10.1016/j.virol.2009.08.030
Immunosuppression and increased susceptibility to Japaneses B encephalitis virus in Trichinella spiralis-infected mice

Journal Article Cypess, R H ; Lubiniecki, A S ; Hammon, W M - Proc. Soc. Exp. Biol. Med., v. 143, no. 2, pp. 469-473
DOI: 10.3181/00379727-143-37345

Similar Records