Achieving the desired outcome
Abstract
We present the scenario states that buprenorphine is administered to rodents as a negative control in a study evaluating the efficacy of certain new synthetic opioids; however, a nationwide shortage of buprenorphine has occurred. The IACUC is faced with the challenge of trying to decide if it is acceptable for Dr. Rosenfeld to use outdated buprenorphine or a buprenorphine reference standard to complete her study. The IACUC’s policy on veterinary verification and consultation (VVC) is not provided in this scenario, but it seems unlikely that the policy would address the use of either a reference standard or an expired drug, so the Attending Veterinarian was correct in referring the request to the full committee.
- Authors:
-
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Publication Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1471855
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- LabAnimal
- Additional Journal Information:
- Journal Volume: 47; Journal Issue: 6; Journal ID: ISSN 0093-7355
- Publisher:
- Springer Nature
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Richerson, Joan T., and Glass-Mattie, Dana. Achieving the desired outcome. United States: N. p., 2018.
Web. doi:10.1038/s41684-018-0068-x.
Richerson, Joan T., & Glass-Mattie, Dana. Achieving the desired outcome. United States. https://doi.org/10.1038/s41684-018-0068-x
Richerson, Joan T., and Glass-Mattie, Dana. Wed .
"Achieving the desired outcome". United States. https://doi.org/10.1038/s41684-018-0068-x. https://www.osti.gov/servlets/purl/1471855.
@article{osti_1471855,
title = {Achieving the desired outcome},
author = {Richerson, Joan T. and Glass-Mattie, Dana},
abstractNote = {We present the scenario states that buprenorphine is administered to rodents as a negative control in a study evaluating the efficacy of certain new synthetic opioids; however, a nationwide shortage of buprenorphine has occurred. The IACUC is faced with the challenge of trying to decide if it is acceptable for Dr. Rosenfeld to use outdated buprenorphine or a buprenorphine reference standard to complete her study. The IACUC’s policy on veterinary verification and consultation (VVC) is not provided in this scenario, but it seems unlikely that the policy would address the use of either a reference standard or an expired drug, so the Attending Veterinarian was correct in referring the request to the full committee.},
doi = {10.1038/s41684-018-0068-x},
journal = {LabAnimal},
number = 6,
volume = 47,
place = {United States},
year = {2018},
month = {5}
}
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