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Title: Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts

Authors:
 [1];  [1];  [1];  [1];  [1];  [1]
  1. Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge MA 02139 USA
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1469026
Grant/Contract Number:  
FG02-08ER46488 Mod 0008
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
Small
Additional Journal Information:
Journal Name: Small Journal Volume: 14 Journal Issue: 44; Journal ID: ISSN 1613-6810
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
Germany
Language:
English

Citation Formats

Lew, Tedrick Thomas Salim, Wong, Min Hao, Kwak, Seon-Yeong, Sinclair, Rosalie, Koman, Volodymyr B., and Strano, Michael S. Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts. Germany: N. p., 2018. Web. doi:10.1002/smll.201802086.
Lew, Tedrick Thomas Salim, Wong, Min Hao, Kwak, Seon-Yeong, Sinclair, Rosalie, Koman, Volodymyr B., & Strano, Michael S. Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts. Germany. doi:10.1002/smll.201802086.
Lew, Tedrick Thomas Salim, Wong, Min Hao, Kwak, Seon-Yeong, Sinclair, Rosalie, Koman, Volodymyr B., and Strano, Michael S. Thu . "Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts". Germany. doi:10.1002/smll.201802086.
@article{osti_1469026,
title = {Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts},
author = {Lew, Tedrick Thomas Salim and Wong, Min Hao and Kwak, Seon-Yeong and Sinclair, Rosalie and Koman, Volodymyr B. and Strano, Michael S.},
abstractNote = {},
doi = {10.1002/smll.201802086},
journal = {Small},
number = 44,
volume = 14,
place = {Germany},
year = {2018},
month = {9}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1002/smll.201802086

Citation Metrics:
Cited by: 6 works
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Melchers, Georg</span> </li> <li> Planta, Vol. 142, Issue 2</li> <li> <span class="text-muted related-url">DOI: <a href="https://doi.org/10.1007/BF00388219" class="text-muted" target="_blank" rel="noopener noreferrer">10.1007/BF00388219<span class="fa fa-external-link" aria-hidden="true"></span></a></span> </li> </ul> <hr/> </div><div> <h2 class="title" style="margin-bottom:0;" data-apporder=""> <a href="https://doi.org/10.1021/nn800325a" target="_blank" rel="noopener noreferrer" class="name">Carbon Nanotubes Protect DNA Strands during Cellular Delivery<span class="fa fa-external-link" aria-hidden="true"></span></a> <small class="text-muted" style="text-transform:uppercase; font-size:0.75rem;"><br/> <span class="type">journal</span>, <span class="date" data-date="2008-10-08">October 2008</span></small> </h2> <ul class="small references-list" style="list-style-type:none; margin-top: 0.5em; padding-left: 0; line-height:1.8em;"> <li> <span style="color:#5C7B2D;"> Wu, Yanrong; Phillips, Joseph A.; Liu, Haipeng</span> </li> <li> ACS Nano, Vol. 2, Issue 10</li> <li> <span class="text-muted related-url">DOI: <a href="https://doi.org/10.1021/nn800325a" class="text-muted" target="_blank" rel="noopener noreferrer">10.1021/nn800325a<span class="fa fa-external-link" aria-hidden="true"></span></a></span> </li> </ul> <hr/> </div></div> <div class="pagination-container small"> <a class="pure-button prev page" href="#" rel="prev"><span class="fa fa-angle-left"></span></a><ul class="pagination d-inline-block" style="padding-left:.2em;"></ul><a class="pure-button next page" href="#" rel="next"><span class="fa fa-angle-right"></span></a> </div> </div> </div> <div class="col-sm-3 order-sm-3"> <ul class="nav nav-stacked"> <li class="active"><a href="" class="reference-type-filter tab-nav" data-tab="biblio-references" data-filter="type" data-pattern="*"><span class="fa fa-angle-right"></span> All References</a></li> <li class="small" style="margin-left:.75em; text-transform:capitalize;"><a href="" class="reference-type-filter tab-nav" data-tab="biblio-references" data-filter="type" data-pattern="journal"><span class="fa fa-angle-right"></span> journal<small class="text-muted"> (82)</small></a></li> </ul> <div style="margin-top:2em;"> <form class="pure-form small text-muted reference-search"> <label for="reference-search-text" class="sr-only">Search</label> <input class="search form-control pure-input-1" id="reference-search-text" placeholder="Search" style="margin-bottom:10px;" /> <fieldset> <div style="margin-left:1em; 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margin-top:0px;">Similar Records in DOE PAGES and OSTI.GOV collections:</p> <aside> <ul class="item-list" itemscope itemtype="http://schema.org/ItemList" style="padding-left:0; list-style-type: none;"> <li> <div class="article item document" itemprop="itemListElement" itemscope itemtype="http://schema.org/WebPage"><meta itemprop="position" content="0" /><div class="item-info"> <h2 class="title" itemprop="name headline"><a href="/biblio/1609981-rational-design-principles-transport-subcellular-distribution-nanomaterials-plant-protoplasts" itemprop="url">Rational Design Principles for the Transport and Subcellular Distribution of Nanomaterials into Plant Protoplasts</a></h2> <div class="metadata"> <small class="text-muted" style="text-transform:uppercase;display:block;line-height:2.5em;">Journal Article</small><span class="authors"> <span class="author">Lew, Tedrick Thomas Salim</span> ; <span class="author">Wong, Min Hao</span> ; <span class="author">Kwak, Seon-Yeong</span> ; <span class="author">...</span> <span class="text-muted pubdata"> - Small</span> </span> </div> <div class="abstract">Not provided.</div><div class="metadata-links small clearfix text-muted" style="margin-top:15px;"> <div class="pure-menu pure-menu-horizontal pull-right" style="width:unset;"> <ul class="pure-menu-list"> <li class="pure-menu-item"><span class="item-info-ftlink">DOI: <a class="misc doi-link " href="https://doi.org/10.1002/smll.201802086" target="_blank" rel="noopener" title="Link to document DOI" data-ostiid="1609981" data-product-type="Journal Article" data-product-subtype="AC" >10.1002/smll.201802086</a></span></li> </ul> </div> </div> </div> <div class="clearfix"></div> </div> </li> <li> <div class="article item document" itemprop="itemListElement" itemscope itemtype="http://schema.org/WebPage"><meta itemprop="position" content="2" /><div class="item-info"> <h2 class="title" itemprop="name headline"><a href="/pages/biblio/1506633-effect-ceo2-nanomaterial-surface-functional-groups-tissue-subcellular-distribution-ce-tomato-solanum-lycopersicum" itemprop="url">Effect of CeO <sub>2</sub> nanomaterial surface functional groups on tissue and subcellular distribution of Ce in tomato ( <em>Solanum lycopersicum</em>)</a></h2> <div class="metadata"> <small class="text-muted" style="text-transform:uppercase;display:block;line-height:2.5em;">Journal Article</small><span class="authors"> <span class="author">Li, Jieran</span> ; <span class="author">Tappero, Ryan V.</span> ; <span class="author">Acerbo, Alvin S.</span> ; <span class="author">...</span> <span class="text-muted pubdata"> - Environmental Science: Nano</span> </span> </div> <div class="abstract">Using recent advances in X-ray microscopy, this study aimed to elucidate mechanisms of uptake, subcellular distribution, and translocation of functionalized CeO <sub>2</sub> MNM (manufactured nanomaterials), having different charges, by tomato plants ( <em>Solanum lycopersicum</em> cv Micro-Tom). As a result, we found that plant growth and Ce concentration in tissues were functions of surface charge and exposure concentration with root to shoot translocation being much greater for negatively charged CeO <sub>2</sub> than positive or neutral CeO <sub>2</sub>. Mechanisms of entry into roots and translocation within plants were examined using X-ray nano- and microprobes. There were dramatic differences in the tissue and<a href='#' onclick='$(this).hide().next().show().next().show();return false;' style='margin-left:10px;'>more »</a><span style='display:none;'> subcellular distributions of Ce in plant roots exposed to dextran-coated CeO <sub>2</sub> nanoparticles conjugated with positive, neutral and negative functional groups. Positively charged CeO <sub>2</sub> remained mainly bound to the epidermis of the root with little present in the apoplast or cytoplasm. Negatively charged CeO <sub>2</sub> was found in the cytoplasm throughout the root cross section, and negatively charged CeO <sub>2</sub> was found within the apoplast in the cortex and both the apoplast and the cytoplasm in the vasculature. Neutral CeO <sub>2</sub> likely entered through the gaps between epidermal cells being sloughed off during root growth and penetrated deeper into the interior of the roots (vasculature) via a combination of apoplastic and symplastic transport. Evidence of symplastic Ce transport was observed with the neutrally and negatively charged particles. We observed evidence of endocytosis as the mechanism for entry into the symplast allowing for entry into the xylem. Finally, this study provides critical information on how particle surface chemistry influences the biodistribution and cellular localization of nanomaterials in plants and is to date the highest resolution X-ray imaging of nanomaterials in plant cells.</span><a href='#' onclick='$(this).hide().prev().hide().prev().show();return false;' style='margin-left:10px;display:none;'>« less</a></div><div class="metadata-links small clearfix text-muted" style="margin-top:15px;"> <span class="fa fa-book text-muted" aria-hidden="true"></span> Cited by 8<div class="pure-menu pure-menu-horizontal pull-right" style="width:unset;"> <ul class="pure-menu-list"> <li class="pure-menu-item"><span class="item-info-ftlink">DOI: <a class="misc doi-link " href="https://doi.org/10.1039/C8EN01287C" target="_blank" rel="noopener" title="Link to document DOI" data-ostiid="1506633" data-product-type="Journal Article" data-product-subtype="AM" >10.1039/C8EN01287C</a></span></li> <li class="pure-menu-item"><span class="item-info-ftlink"><a class="misc fulltext-link " href="/pages/servlets/purl/1506633" title="Link to document media" target="_blank" rel="noopener" data-ostiid="1506633" data-product-type="Journal Article" data-product-subtype="AM" >Full Text Available</a></span></li> </ul> </div> </div> </div> <div class="clearfix"></div> </div> </li> <li> <div class="article item document" itemprop="itemListElement" itemscope itemtype="http://schema.org/WebPage"><meta itemprop="position" content="3" /><div class="item-info"> <h2 class="title" itemprop="name headline"><a href="/biblio/1493780-effect-ceo2-nanomaterial-surface-functional-groups-tissue-subcellular-distribution-ce-tomato-solanum-lycopersicum" itemprop="url">Effect of CeO <sub>2</sub> nanomaterial surface functional groups on tissue and subcellular distribution of Ce in tomato ( <em>Solanum lycopersicum</em>)</a></h2> <div class="metadata"> <small class="text-muted" style="text-transform:uppercase;display:block;line-height:2.5em;">Journal Article</small><span class="authors"> <span class="author">Li, Jieran</span> ; <span class="author">Tappero, Ryan V.</span> ; <span class="author">Acerbo, Alvin S.</span> ; <span class="author">...</span> <span class="text-muted pubdata"> - Environmental Science: Nano</span> </span> </div> <div class="abstract">Using recent advances in X-ray microscopy, this study aimed to elucidate mechanisms of uptake, subcellular distribution, and translocation of functionalized CeO <sub>2</sub>MNM (manufactured nanomaterials), having different charges, by tomato plants ( <em>Solanum lycopersicum</em>cv Micro-Tom).</div><div class="metadata-links small clearfix text-muted" style="margin-top:15px;"> <div class="pure-menu pure-menu-horizontal pull-right" style="width:unset;"> <ul class="pure-menu-list"> <li class="pure-menu-item"><span class="item-info-ftlink">DOI: <a class="misc doi-link " href="https://doi.org/10.1039/c8en01287c" target="_blank" rel="noopener" title="Link to document DOI" data-ostiid="1493780" data-product-type="Journal Article" data-product-subtype="AC" >10.1039/c8en01287c</a></span></li> </ul> </div> </div> </div> <div class="clearfix"></div> </div> </li> <li> <div class="article item document" itemprop="itemListElement" itemscope itemtype="http://schema.org/WebPage"><meta itemprop="position" content="4" /><div class="item-info"> <h2 class="title" itemprop="name headline"><a href="/biblio/1535070-nitroaromatic-detection-infrared-communication-from-wild-type-plants-using-plantnanobionics" itemprop="url">Nitroaromatic detection and infrared communication from wild-type plants using plant nanobionics</a></h2> <div class="metadata"> <small class="text-muted" style="text-transform:uppercase;display:block;line-height:2.5em;">Journal Article</small><span class="authors"> <span class="author">Wong, Min Hao</span> ; <span class="author">Giraldo, Juan P.</span> ; <span class="author">Kwak, Seon-Yeong</span> ; <span class="author">...</span> <span class="text-muted pubdata"> - Nature Materials</span> </span> </div> <div class="abstract">Not provided.</div><div class="metadata-links small clearfix text-muted" style="margin-top:15px;"> <div class="pure-menu pure-menu-horizontal pull-right" style="width:unset;"> <ul class="pure-menu-list"> <li class="pure-menu-item"><span class="item-info-ftlink">DOI: <a class="misc doi-link " href="https://doi.org/10.1038/nmat4771" target="_blank" rel="noopener" title="Link to document DOI" data-ostiid="1535070" data-product-type="Journal Article" data-product-subtype="AC" >10.1038/nmat4771</a></span></li> </ul> </div> </div> </div> <div class="clearfix"></div> </div> </li> <li> <div class="article item document" itemprop="itemListElement" itemscope itemtype="http://schema.org/WebPage"><meta itemprop="position" content="5" /><div class="item-info"> <h2 class="title" itemprop="name headline"><a href="/biblio/4183228-heavy-water-moderated-power-reactor-plants-design-study" itemprop="url">HEAVY WATER MODERATED POWER REACTOR PLANTS--DESIGN STUDY</a></h2> <div class="metadata"> <small class="text-muted" style="text-transform:uppercase;display:block;line-height:2.5em;">Technical Report</small><span class="authors"> <span class="text-muted pubdata"></span> </span> </div> <div class="abstract">Studies of basic design parameters for heavy water moderated reactor plants and systems of prototype plants and further development program requirements are examined. The general objective was to assure maximum utilization of currently available information in the design of the components and systems of the plants. While each part of the study was evaluated in terms of its effect on the plsnt design, as well as other factors related to performance cbaracteristics, construction, operating costs, and the constraction schedule; it is a general conclusion that no major changes are required in the design of either the prototype plant or the<a href='#' onclick='$(this).hide().next().show().next().show();return false;' style='margin-left:10px;'>more »</a><span style='display:none;'> full-scale plant on the basis of the parameters studied. To this extent, the studies provided confirmation of the major decisions affecting plant designs which were made during Parts 1 and 2 of the study. 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