Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy

Liu, Wei; Fu, Li; Wang, Zhuguang; Sohrabpour, Zahra; Li, Xiaobai; Liu, Yuting; Wang, Hong-fei; Yan, Elsa C. Y.

doi:10.1039/C7CP07061F

Title: Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy

Abstract

Vibrational sum frequency generation studies demonstrate the effects of two-dimensional molecular crowding on protein folding at interfaces.

Authors:

Liu, Wei ^[1]; Fu, Li ^[1]; Wang, Zhuguang ^[1]; Sohrabpour, Zahra ^[1]; Li, Xiaobai ^[1]; Liu, Yuting ^[1];

^[2];

^[1]

Department of Chemistry, Yale University, New Haven, USA
Department of Chemistry, Fudan University, Shanghai 200433, China

Publication Date:: Mon Jan 01 00:00:00 EST 2018

Sponsoring Org.:: USDOE Office of Science (SC), Biological and Environmental Research (BER)

OSTI Identifier:: 1467748

Resource Type:: Publisher's Accepted Manuscript

Journal Name:: Physical Chemistry Chemical Physics. PCCP

Additional Journal Information:: Journal Name: Physical Chemistry Chemical Physics. PCCP Journal Volume: 20 Journal Issue: 35; Journal ID: ISSN 1463-9076

Publisher:: Royal Society of Chemistry (RSC)

Country of Publication:: United Kingdom

Language:: English

Citation Formats


                    Liu, Wei, Fu, Li, Wang, Zhuguang, Sohrabpour, Zahra, Li, Xiaobai, Liu, Yuting, Wang, Hong-fei, and Yan, Elsa C. Y. Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy.  United Kingdom: N. p., 2018. 
Web.  doi:10.1039/C7CP07061F.

Copy to clipboard


                    Liu, Wei, Fu, Li, Wang, Zhuguang, Sohrabpour, Zahra, Li, Xiaobai, Liu, Yuting, Wang, Hong-fei, & Yan, Elsa C. Y. Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy.  United Kingdom.  https://doi.org/10.1039/C7CP07061F

Copy to clipboard


                    Liu, Wei, Fu, Li, Wang, Zhuguang, Sohrabpour, Zahra, Li, Xiaobai, Liu, Yuting, Wang, Hong-fei, and Yan, Elsa C. Y. Mon .  
"Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy".  United Kingdom.  https://doi.org/10.1039/C7CP07061F.

Copy to clipboard


                    
@article{osti_1467748,

  title        = {Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy},

  author       = {Liu, Wei and Fu, Li and Wang, Zhuguang and Sohrabpour, Zahra and Li, Xiaobai and Liu, Yuting and Wang, Hong-fei and Yan, Elsa C. Y.},

  abstractNote = {Vibrational sum frequency generation studies demonstrate the effects of two-dimensional molecular crowding on protein folding at interfaces.},

  doi          = {10.1039/C7CP07061F},

  journal      = {Physical Chemistry Chemical Physics. PCCP},

  number       = 35,

  volume       = 20,

  place        = {United Kingdom},

  year         = {Mon Jan 01 00:00:00 EST 2018},

  month        = {Mon Jan 01 00:00:00 EST 2018}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Accepted Manuscript (Publisher)

Publisher's Version of Record
https://doi.org/10.1039/C7CP07061F

Other availability

Search WorldCat to find libraries that may hold this journal

Citation Metrics:

Cited by: 18 works

Citation information provided by
Web of Science

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

Detection of chiral sum frequency generation vibrational spectra of proteins and peptides at interfaces in situ
journal, March 2005

Wang, J.; Chen, X.; Clarke, M. L.
Proceedings of the National Academy of Sciences, Vol. 102, Issue 14
DOI: 10.1073/pnas.0501206102

Macromolecular Crowding at Membrane Interfaces: Adsorption and Alignment of Membrane Peptides
journal, January 2008

Aisenbrey, Christopher; Bechinger, Burkhard; Gröbner, Gerhard
Journal of Molecular Biology, Vol. 375, Issue 2
DOI: 10.1016/j.jmb.2007.10.053

What vibrations tell about proteins
journal, November 2002

Barth, Andreas; Zscherp, Christian
Quarterly Reviews of Biophysics, Vol. 35, Issue 4
DOI: 10.1017/S0033583502003815

Ultrafast Reorientational Dynamics of Leucine at the Air–Water Interface
journal, January 2016

Donovan, Michael A.; Yimer, Yeneneh Y.; Pfaendtner, Jim
Journal of the American Chemical Society, Vol. 138, Issue 16
DOI: 10.1021/jacs.6b01878

Electronic and Vibrational Second-Order Nonlinear Optical Properties of Protein Secondary Structural Motifs
journal, October 2005

Perry, John M.; Moad, Andrew J.; Begue, Nathan J.
The Journal of Physical Chemistry B, Vol. 109, Issue 42
DOI: 10.1021/jp0506888

Protein Diffusion and Macromolecular Crowding in Thylakoid Membranes
journal, February 2008

Kirchhoff, Helmut; Haferkamp, Silvia; Allen, John F.
Plant Physiology, Vol. 146, Issue 4
DOI: 10.1104/pp.107.115170

Crowding Effects on Diffusion in Solutions and Cells
journal, June 2008

Dix, James A.; Verkman, A. S.
Annual Review of Biophysics, Vol. 37, Issue 1
DOI: 10.1146/annurev.biophys.37.032807.125824

N-H Stretching Modes Around 3300 Wavenumber From Peptide Backbones Observed by Chiral Sum Frequency Generation Vibrational Spectroscopy: N-H STRETCH IN PROTEIN PROBED BY CHIRAL SFG
journal, March 2014

Fu, Li; Wang, Zhuguang; Yan, Elsa C. Y.
Chirality, Vol. 26, Issue 9
DOI: 10.1002/chir.22306

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences
journal, June 2008

Zhou, Huan-Xiang; Rivas, Germán; Minton, Allen P.
Annual Review of Biophysics, Vol. 37, Issue 1, p. 375-397
DOI: 10.1146/annurev.biophys.37.032807.125817

Protein folding by the effects of macromolecular crowding
journal, January 2004

Tokuriki, N.
Protein Science, Vol. 13, Issue 1
DOI: 10.1110/ps.03288104

Steric confinement of proteins on lipid membranes can drive curvature and tubulation
journal, April 2010

Stachowiak, Jeanne C.; Hayden, Carl C.; Sasaki, Darryl Y.
Proceedings of the National Academy of Sciences, Vol. 107, Issue 17
DOI: 10.1073/pnas.0913306107

DNA’s Chiral Spine of Hydration
journal, May 2017

McDermott, M. Luke; Vanselous, Heather; Corcelli, Steven A.
ACS Central Science, Vol. 3, Issue 7
DOI: 10.1021/acscentsci.7b00100

Ultrafast Vibrational Dynamics of Membrane-Bound Peptides at the Lipid Bilayer/Water Interface
journal, September 2017

Tan, Junjun; Zhang, Baixiong; Luo, Yi
Angewandte Chemie International Edition, Vol. 56, Issue 42
DOI: 10.1002/anie.201706996

NMR Structure of Transcription Factor Sp1 DNA Binding Domain ^† ^, ^‡
journal, December 2004

Oka, Shinichiro; Shiraishi, Yasuhisa; Yoshida, Takuya
Biochemistry, Vol. 43, Issue 51
DOI: 10.1021/bi048438p

Polarized infrared spectroscopy of oriented purple membrane
journal, March 1979

Rothschild, K. J.; Clark, N. A.
Biophysical Journal, Vol. 25, Issue 3
DOI: 10.1016/S0006-3495(79)85317-5

Lipids on the frontier: a century of cell-membrane bilayers
journal, May 2003

Edidin, Michael
Nature Reviews Molecular Cell Biology, Vol. 4, Issue 5
DOI: 10.1038/nrm1102

Adding a dimension to the infrared spectra of interfaces using heterodyne detected 2D sum-frequency generation (HD 2D SFG) spectroscopy
journal, December 2011

Xiong, W.; Laaser, J. E.; Mehlenbacher, R. D.
Proceedings of the National Academy of Sciences, Vol. 108, Issue 52
DOI: 10.1073/pnas.1115055108

Membrane bending by protein–protein crowding
journal, August 2012

Stachowiak, Jeanne C.; Schmid, Eva M.; Ryan, Christopher J.
Nature Cell Biology, Vol. 14, Issue 9
DOI: 10.1038/ncb2561

Macromolecular crowding: obvious but underappreciated
journal, October 2001

Ellis, R. John
Trends in Biochemical Sciences, Vol. 26, Issue 10
DOI: 10.1016/S0968-0004(01)01938-7

Chiral Sum Frequency Generation Spectroscopy for Characterizing Protein Secondary Structures at Interfaces
journal, June 2011

Fu, Li; Liu, Jian; Yan, Elsa C. Y.
Journal of the American Chemical Society, Vol. 133, Issue 21
DOI: 10.1021/ja201575e

Proteins at Interfaces Probed by Chiral Vibrational Sum Frequency Generation Spectroscopy
journal, January 2015

Yan, Elsa C. Y.; Wang, Zhuguang; Fu, Li
The Journal of Physical Chemistry B, Vol. 119, Issue 7
DOI: 10.1021/jp508926e

Lipid glycosylation: a primer for histochemists and cell biologists
journal, December 2016

Kopitz, Jürgen
Histochemistry and Cell Biology, Vol. 147, Issue 2
DOI: 10.1007/s00418-016-1518-4

C−H Stretching Vibrations of Methyl, Methylene and Methine Groups at the Vapor/Alcohol ( n = 1−8) Interfaces
journal, July 2005

Lu, Rong; Gan, Wei; Wu, Bao-hua
The Journal of Physical Chemistry B, Vol. 109, Issue 29
DOI: 10.1021/jp051565q

Effect of Macromolecular Crowding on Protein Folding Dynamics at the Secondary Structure Level
journal, October 2009

Mukherjee, Smita; Waegele, Matthias M.; Chowdhury, Pramit
Journal of Molecular Biology, Vol. 393, Issue 1
DOI: 10.1016/j.jmb.2009.08.016

Biological Macromolecules at Interfaces Probed by Chiral Vibrational Sum Frequency Generation Spectroscopy
journal, January 2014

Yan, Elsa C. Y.; Fu, Li; Wang, Zhuguang
Chemical Reviews, Vol. 114, Issue 17
DOI: 10.1021/cr4006044

Misfolding of Amyloidogenic Proteins at Membrane Surfaces: The Impact of Macromolecular Crowding
journal, December 2007

Bokvist, Marcus; Gröbner, Gerhard
Journal of the American Chemical Society, Vol. 129, Issue 48
DOI: 10.1021/ja076059o

Liquid Interfaces Probed by Second-Harmonic and Sum-Frequency Spectroscopy
journal, January 1996

Eisenthal, K. B.
Chemical Reviews, Vol. 96, Issue 4
DOI: 10.1021/cr9502211

Heterodyne-Detected Vibrational Sum Frequency Generation Spectroscopy
journal, February 2008

Stiopkin, Igor V.; Jayathilake, Himali D.; Bordenyuk, Andrey N.
Journal of the American Chemical Society, Vol. 130, Issue 7
DOI: 10.1021/ja076708w

Oriented secondary structure in integral membrane proteins. I. Circular dichroism and infrared spectroscopy of cytochrome oxidase in multilamellar films
journal, December 1985

Bazzi, M. D.; Woody, R. W.
Biophysical Journal, Vol. 48, Issue 6
DOI: 10.1016/S0006-3495(85)83859-5

Heterodyne-Detected Achiral and Chiral Vibrational Sum Frequency Generation of Proteins at Air/Water Interface
journal, April 2015

Okuno, Masanari; Ishibashi, Taka-aki
The Journal of Physical Chemistry C, Vol. 119, Issue 18
DOI: 10.1021/acs.jpcc.5b01937

‘Zinc fingers’: a novel protein motif for nucleic acid recognition
journal, January 1987

Klug, Aaron; Rhodes, Daniela
Trends in Biochemical Sciences, Vol. 12
DOI: 10.1016/0968-0004(87)90231-3

¹⁵ N NMR Spin Relaxation Dispersion Study of the Molecular Crowding Effects on Protein Folding under Native Conditions
journal, March 2006

Ai, Xuanjun; Zhou, Zheng; Bai, Yawen
Journal of the American Chemical Society, Vol. 128, Issue 12
DOI: 10.1021/ja057832n

Chiral Vibrational Structures of Proteins at Interfaces Probed by Sum Frequency Generation Spectroscopy
journal, December 2011

Fu, Li; Wang, Zhuguang; Yan, Elsa C. Y.
International Journal of Molecular Sciences, Vol. 12, Issue 12
DOI: 10.3390/ijms12129404

Investigation of Surfactant Conformation and Order at the Liquid−Liquid Interface by Total Internal Reflection Sum-Frequency Vibrational Spectroscopy
journal, January 1996

Conboy, John C.; Messmer, Marie C.; Richmond, Geraldine L.
The Journal of Physical Chemistry, Vol. 100, Issue 18
DOI: 10.1021/jp953616x

Heterodyne-detected electronic sum frequency generation: “Up” versus “down” alignment of interfacial molecules
journal, September 2008

Yamaguchi, Shoichi; Tahara, Tahei
The Journal of Chemical Physics, Vol. 129, Issue 10
DOI: 10.1063/1.2981179

Specificity of lipid-protein interactions as determined by spectroscopic techniques
journal, June 1985

Devaux, Philippe F.; Seigneuret, Michel
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, Vol. 822, Issue 1
DOI: 10.1016/0304-4157(85)90004-8

A Unified Treatment of Selection Rules and Symmetry Relations for Sum-Frequency and Second Harmonic Spectroscopies
journal, March 2004

Moad, Andrew J.; Simpson, Garth J.
The Journal of Physical Chemistry B, Vol. 108, Issue 11
DOI: 10.1021/jp035362i

Identification of the response of protein N–H vibrations in vibrational sum-frequency generation spectroscopy of aqueous protein films
journal, January 2017

Meister, K.; Paananen, A.; Bakker, H. J.
Physical Chemistry Chemical Physics, Vol. 19, Issue 17
DOI: 10.1039/C6CP08325K

Membrane bending by protein crowding is affected by protein lateral confinement
journal, June 2016

Derganc, Jure; Čopič, Alenka
Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1858, Issue 6
DOI: 10.1016/j.bbamem.2016.03.009

Adsorption and conformation variation of BSA protein with the size variation of the metallic nanoparticles in LB film
journal, March 2015

Das, Kaushik; Kundu, Sarathi
Colloids and Surfaces A: Physicochemical and Engineering Aspects, Vol. 468
DOI: 10.1016/j.colsurfa.2014.12.007

Making “Sense” of DNA
journal, June 2007

Stokes, Grace Y.; Gibbs-Davis, Julianne M.; Boman, Faith C.
Journal of the American Chemical Society, Vol. 129, Issue 24
DOI: 10.1021/ja071848r

Chirality in Nonlinear Optics
journal, May 2009

Haupert, Levi M.; Simpson, Garth J.
Annual Review of Physical Chemistry, Vol. 60, Issue 1
DOI: 10.1146/annurev.physchem.59.032607.093712

Infrared spectroscopy of proteins and peptides in lipid bilayers
journal, November 1997

Tamm, Lukas K.; Tatulian, Suren A.
Quarterly Reviews of Biophysics, Vol. 30, Issue 4
DOI: 10.1017/S0033583597003375

Lipid A Modification Systems in Gram-Negative Bacteria
journal, June 2007

Raetz, Christian R. H.; Reynolds, C. Michael; Trent, M. Stephen
Annual Review of Biochemistry, Vol. 76, Issue 1
DOI: 10.1146/annurev.biochem.76.010307.145803

Inhomogeneous and Spontaneous Formation of Chirality in the Langmuir Monolayer of Achiral Molecules at the Air/Water Interface Probed by In Situ Surface Second Harmonic Generation Linear Dichroism
journal, February 2009

Xu, Yan-yan; Rao, Yi; Zheng, De-sheng
The Journal of Physical Chemistry C, Vol. 113, Issue 10
DOI: 10.1021/jp810509u

Quantitative spectral and orientational analysis in surface sum frequency generation vibrational spectroscopy (SFG-VS)
journal, April 2005

Wang *, Hong-Fei; Gan † ‡, Wei; Lu † ‡ §, Rong
International Reviews in Physical Chemistry, Vol. 24, Issue 2
DOI: 10.1080/01442350500225894

The transmembrane domains of the nicotinic acetylcholine receptor contain alpha-helical and beta structures.
journal, January 1994

Görne-Tschelnokow, U.; Strecker, A.; Kaduk, C.
The EMBO Journal, Vol. 13, Issue 2
DOI: 10.1002/j.1460-2075.1994.tb06266.x

Crowding Effects of Membrane Proteins
journal, June 2009

Zhou, Huan-Xiang
The Journal of Physical Chemistry B, Vol. 113, Issue 23
DOI: 10.1021/jp8107446

Intrinsic Chirality and Prochirality at Air/R-(+)- and S-(-)-Limonene Interfaces: Spectral Signatures With Interference Chiral Sum-Frequency Generation Vibrational Spectroscopy: INTRINSIC CHIRALITY AND PROCHIRALITY AT AIR/R-(+)- AND S-(-)-LIMONENE INTERFACES
journal, June 2014

Fu, Li; Zhang, Yun; Wei, Zhe-Hao
Chirality, Vol. 26, Issue 9
DOI: 10.1002/chir.22337

Broad-Bandwidth Chiral Sum Frequency Generation Spectroscopy for Probing the Kinetics of Proteins at Interfaces
journal, July 2015

Wang, Zhuguang; Fu, Li; Ma, Gang
Langmuir, Vol. 31, Issue 42
DOI: 10.1021/acs.langmuir.5b02100

Surface properties probed by second-harmonic and sum-frequency generation
journal, February 1989

Shen, Y. R.
Nature, Vol. 337, Issue 6207
DOI: 10.1038/337519a0

Sticky water surfaces: Helix–coil transitions suppressed in a cell-penetrating peptide at the air-water interface
journal, December 2014

Schach, Denise; Globisch, Christoph; Roeters, Steven J.
The Journal of Chemical Physics, Vol. 141, Issue 22
DOI: 10.1063/1.4898711

DPPC Langmuir Monolayer at the Air−Water Interface: Probing the Tail and Head Groups by Vibrational Sum Frequency Generation Spectroscopy
journal, June 2006

Ma, Gang; Allen, Heather C.
Langmuir, Vol. 22, Issue 12
DOI: 10.1021/la0535227

Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell
journal, August 2000

van den Berg, Bert; Wain, Rachel; Dobson, Christopher M.
The EMBO Journal, Vol. 19, Issue 15
DOI: 10.1093/emboj/19.15.3870

Amide I Two-Dimensional Infrared Spectroscopy of Proteins
journal, March 2008

Ganim, Ziad; Chung, Hoi Sung; Smith, Adam W.
Accounts of Chemical Research, Vol. 41, Issue 3
DOI: 10.1021/ar700188n

Molecular Bonding and Interactions at Aqueous Surfaces as Probed by Vibrational Sum Frequency Spectroscopy
journal, August 2002

Richmond, G. L.
Chemical Reviews, Vol. 102, Issue 8
DOI: 10.1021/cr0006876

Dissociative Binding of Carboxylic Acid Ligand on Nanoceria Surface in Aqueous Solution: A Joint In Situ Spectroscopic Characterization and First-Principles Study
journal, November 2013

Lu, Zhou; Karakoti, Ajay; Velarde, Luis
The Journal of Physical Chemistry C, Vol. 117, Issue 46
DOI: 10.1021/jp4068747

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment
journal, September 2015

Schach, Denise K.; Rock, William; Franz, Johannes
Journal of the American Chemical Society, Vol. 137, Issue 38
DOI: 10.1021/jacs.5b06720

Similar Records in DOE PAGES and OSTI.GOV collections:

Characterization of the molecular structure and mechanical properties of polymer surfaces and protein/polymer interfaces by sum frequency generation vibrational spectroscopy and atomic force microscopy

Thesis/Dissertation Koffas, Telly Stelianos

Sum frequency generation (SFG) vibrational spectroscopy, atomic force microscopy (AFM), and other complementary surface-sensitive techniques have been used to study the surface molecular structure and surface mechanical behavior of biologically-relevant polymer systems. SFG and AFM have emerged as powerful analytical tools to deduce structure/property relationships, in situ, for polymers at air, liquid and solid interfaces. The experiments described in this dissertation have been performed to understand how polymer surface properties are linked to polymer bulk composition, substrate hydrophobicity, changes in the ambient environment (e.g., humidity and temperature), or the adsorption of macromolecules. The correlation of spectroscopic and mechanical data bymore »« less
https://doi.org/10.2172/825532

Full Text Available
Intrinsic Chirality and Prochirality at Air/R-(+)- and S-(-)-Limonene Interfaces: Spectral Signatures with Interference Chiral Sum-Frequency Generation Vibrational Spectroscopy

Journal Article Fu, Li ; Zhang, Yun ; Wei, Zhehao ; ... - Chirality, 26(9):509-520

We report in this work detailed measurements on the chiral and achiral sum-frequency vibrational spectra in the C-H stretching vibration region (2800-3050cm-1) of the air/liquid interfaces of R-limonene and S-limonene, using the recently developed high-resolution broadband sum-frequency generation vibrational spectroscopy (HR-BB-SFG-VS). The achiral SFG spectra of R-limonene and S-limonene, as well as the equal amount (50/50) racemic mixture show that the enantiomers are with the same interfacial orientations. The interference chiral SFG spectra of the limonene enantiomers exhibit spectral signature from chiral response of the Cα-H stretching mode, and spectral signature from prochiral response of the CH2 asymmetric stretching mode,more »« less
https://doi.org/10.1002/chir.22337
Two-dimensional electronic–vibrational sum frequency spectroscopy for interactions of electronic and nuclear motions at interfaces

Journal Article Deng, Gang-Hua ; Qian, Yuqin ; Zhang, Tong ; ... - Proceedings of the National Academy of Sciences of the United States of America

Significance Electronic–vibrational couplings are pivotal in many photo-induced processes at interfaces and surfaces. Two-dimensional electronic–vibrational sum frequency generation spectroscopy is a unique tool to decipher electronic–vibrational couplings for excited states of molecules at interfaces and surfaces, enabling the correlation of photo-induced electronic–vibrational manifolds with their subsequent time evolution of high-frequency vibrational modes. This technique is especially powerful to monitor ultrafast processes such as charge transfer, energy transfer, proton transfer, and proton-coupled charge transfer at interfaces and surfaces on a real-time basis.
https://doi.org/10.1073/pnas.2100608118
Sum Frequency Generation Vibrational Spectroscopy of Adsorbed Amino Acids, Peptides and Proteins of Hydrophilic and Hydrophobic Solid-Water Interfaces

Thesis/Dissertation Holinga IV, George Joseph

Sum frequency generation (SFG) vibrational spectroscopy was used to investigate the interfacial properties of several amino acids, peptides, and proteins adsorbed at the hydrophilic polystyrene solid-liquid and the hydrophobic silica solid-liquid interfaces. The influence of experimental geometry on the sensitivity and resolution of the SFG vibrational spectroscopy technique was investigated both theoretically and experimentally. SFG was implemented to investigate the adsorption and organization of eight individual amino acids at model hydrophilic and hydrophobic surfaces under physiological conditions. Biointerface studies were conducted using a combination of SFG and quartz crystal microbalance (QCM) comparing the interfacial structure and concentration of two aminomore »« less
https://doi.org/10.2172/988994

Full Text Available
Low energy electron diffraction (LEED) and sum frequency generation (SFG) vibrational spectroscopy studies of solid-vacuum, solid-air and solid-liquid interfaces

Thesis/Dissertation Hoffer, Saskia

Electron based surface probing techniques can provide detailed information about surface structure or chemical composition in vacuum environments. The development of new surface techniques has made possible in situ molecular level studies of solid-gas interfaces and more recently, solid-liquid interfaces. The aim of this dissertation is two-fold. First, by using novel sample preparation, Low Energy Electron Diffraction (LEED) and other traditional ultra high vacuum (UHV) techniques are shown to provide new information on the insulator/vacuum interface. The surface structure of the classic insulator NaCl has been determined using these methods. Second, using sum frequency generation (SFG) surface specific vibrational spectroscopymore »« less
https://doi.org/10.2172/803862

Full Text Available

Similar Records

Title: Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy

Abstract

Citation Formats

Detection of chiral sum frequency generation vibrational spectra of proteins and peptides at interfaces in situ journal, March 2005

Macromolecular Crowding at Membrane Interfaces: Adsorption and Alignment of Membrane Peptides journal, January 2008

What vibrations tell about proteins journal, November 2002

Ultrafast Reorientational Dynamics of Leucine at the Air–Water Interface journal, January 2016

Electronic and Vibrational Second-Order Nonlinear Optical Properties of Protein Secondary Structural Motifs journal, October 2005

Protein Diffusion and Macromolecular Crowding in Thylakoid Membranes journal, February 2008

Crowding Effects on Diffusion in Solutions and Cells journal, June 2008

N-H Stretching Modes Around 3300 Wavenumber From Peptide Backbones Observed by Chiral Sum Frequency Generation Vibrational Spectroscopy: N-H STRETCH IN PROTEIN PROBED BY CHIRAL SFG journal, March 2014

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences journal, June 2008

Protein folding by the effects of macromolecular crowding journal, January 2004

Steric confinement of proteins on lipid membranes can drive curvature and tubulation journal, April 2010

DNA’s Chiral Spine of Hydration journal, May 2017

Ultrafast Vibrational Dynamics of Membrane-Bound Peptides at the Lipid Bilayer/Water Interface journal, September 2017

NMR Structure of Transcription Factor Sp1 DNA Binding Domain † , ‡ journal, December 2004

Polarized infrared spectroscopy of oriented purple membrane journal, March 1979

Lipids on the frontier: a century of cell-membrane bilayers journal, May 2003

Adding a dimension to the infrared spectra of interfaces using heterodyne detected 2D sum-frequency generation (HD 2D SFG) spectroscopy journal, December 2011

Membrane bending by protein–protein crowding journal, August 2012

Macromolecular crowding: obvious but underappreciated journal, October 2001

Chiral Sum Frequency Generation Spectroscopy for Characterizing Protein Secondary Structures at Interfaces journal, June 2011

Proteins at Interfaces Probed by Chiral Vibrational Sum Frequency Generation Spectroscopy journal, January 2015

Lipid glycosylation: a primer for histochemists and cell biologists journal, December 2016

C−H Stretching Vibrations of Methyl, Methylene and Methine Groups at the Vapor/Alcohol ( n = 1−8) Interfaces journal, July 2005

Effect of Macromolecular Crowding on Protein Folding Dynamics at the Secondary Structure Level journal, October 2009

Biological Macromolecules at Interfaces Probed by Chiral Vibrational Sum Frequency Generation Spectroscopy journal, January 2014

Misfolding of Amyloidogenic Proteins at Membrane Surfaces: The Impact of Macromolecular Crowding journal, December 2007

Liquid Interfaces Probed by Second-Harmonic and Sum-Frequency Spectroscopy journal, January 1996

Heterodyne-Detected Vibrational Sum Frequency Generation Spectroscopy journal, February 2008

Oriented secondary structure in integral membrane proteins. I. Circular dichroism and infrared spectroscopy of cytochrome oxidase in multilamellar films journal, December 1985

Heterodyne-Detected Achiral and Chiral Vibrational Sum Frequency Generation of Proteins at Air/Water Interface journal, April 2015

‘Zinc fingers’: a novel protein motif for nucleic acid recognition journal, January 1987

15 N NMR Spin Relaxation Dispersion Study of the Molecular Crowding Effects on Protein Folding under Native Conditions journal, March 2006

Chiral Vibrational Structures of Proteins at Interfaces Probed by Sum Frequency Generation Spectroscopy journal, December 2011

Investigation of Surfactant Conformation and Order at the Liquid−Liquid Interface by Total Internal Reflection Sum-Frequency Vibrational Spectroscopy journal, January 1996

Heterodyne-detected electronic sum frequency generation: “Up” versus “down” alignment of interfacial molecules journal, September 2008

Specificity of lipid-protein interactions as determined by spectroscopic techniques journal, June 1985

A Unified Treatment of Selection Rules and Symmetry Relations for Sum-Frequency and Second Harmonic Spectroscopies journal, March 2004

Identification of the response of protein N–H vibrations in vibrational sum-frequency generation spectroscopy of aqueous protein films journal, January 2017

Membrane bending by protein crowding is affected by protein lateral confinement journal, June 2016

Adsorption and conformation variation of BSA protein with the size variation of the metallic nanoparticles in LB film journal, March 2015

Making “Sense” of DNA journal, June 2007

Chirality in Nonlinear Optics journal, May 2009

Infrared spectroscopy of proteins and peptides in lipid bilayers journal, November 1997

Lipid A Modification Systems in Gram-Negative Bacteria journal, June 2007

Inhomogeneous and Spontaneous Formation of Chirality in the Langmuir Monolayer of Achiral Molecules at the Air/Water Interface Probed by In Situ Surface Second Harmonic Generation Linear Dichroism journal, February 2009

Quantitative spectral and orientational analysis in surface sum frequency generation vibrational spectroscopy (SFG-VS) journal, April 2005

The transmembrane domains of the nicotinic acetylcholine receptor contain alpha-helical and beta structures. journal, January 1994

Crowding Effects of Membrane Proteins journal, June 2009

Intrinsic Chirality and Prochirality at Air/R-(+)- and S-(-)-Limonene Interfaces: Spectral Signatures With Interference Chiral Sum-Frequency Generation Vibrational Spectroscopy: INTRINSIC CHIRALITY AND PROCHIRALITY AT AIR/R-(+)- AND S-(-)-LIMONENE INTERFACES journal, June 2014

Broad-Bandwidth Chiral Sum Frequency Generation Spectroscopy for Probing the Kinetics of Proteins at Interfaces journal, July 2015

Surface properties probed by second-harmonic and sum-frequency generation journal, February 1989

Sticky water surfaces: Helix–coil transitions suppressed in a cell-penetrating peptide at the air-water interface journal, December 2014

DPPC Langmuir Monolayer at the Air−Water Interface: Probing the Tail and Head Groups by Vibrational Sum Frequency Generation Spectroscopy journal, June 2006

Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell journal, August 2000

Amide I Two-Dimensional Infrared Spectroscopy of Proteins journal, March 2008

Molecular Bonding and Interactions at Aqueous Surfaces as Probed by Vibrational Sum Frequency Spectroscopy journal, August 2002

Dissociative Binding of Carboxylic Acid Ligand on Nanoceria Surface in Aqueous Solution: A Joint In Situ Spectroscopic Characterization and First-Principles Study journal, November 2013

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment journal, September 2015

Detection of chiral sum frequency generation vibrational spectra of proteins and peptides at interfaces in situ
journal, March 2005

Macromolecular Crowding at Membrane Interfaces: Adsorption and Alignment of Membrane Peptides
journal, January 2008

What vibrations tell about proteins
journal, November 2002

Ultrafast Reorientational Dynamics of Leucine at the Air–Water Interface
journal, January 2016

Electronic and Vibrational Second-Order Nonlinear Optical Properties of Protein Secondary Structural Motifs
journal, October 2005

Protein Diffusion and Macromolecular Crowding in Thylakoid Membranes
journal, February 2008

Crowding Effects on Diffusion in Solutions and Cells
journal, June 2008

N-H Stretching Modes Around 3300 Wavenumber From Peptide Backbones Observed by Chiral Sum Frequency Generation Vibrational Spectroscopy: N-H STRETCH IN PROTEIN PROBED BY CHIRAL SFG
journal, March 2014

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences
journal, June 2008

Protein folding by the effects of macromolecular crowding
journal, January 2004

Steric confinement of proteins on lipid membranes can drive curvature and tubulation
journal, April 2010

DNA’s Chiral Spine of Hydration
journal, May 2017

Ultrafast Vibrational Dynamics of Membrane-Bound Peptides at the Lipid Bilayer/Water Interface
journal, September 2017

NMR Structure of Transcription Factor Sp1 DNA Binding Domain ^† ^, ^‡
journal, December 2004

Polarized infrared spectroscopy of oriented purple membrane
journal, March 1979

Lipids on the frontier: a century of cell-membrane bilayers
journal, May 2003

Adding a dimension to the infrared spectra of interfaces using heterodyne detected 2D sum-frequency generation (HD 2D SFG) spectroscopy
journal, December 2011

Membrane bending by protein–protein crowding
journal, August 2012

Macromolecular crowding: obvious but underappreciated
journal, October 2001

Chiral Sum Frequency Generation Spectroscopy for Characterizing Protein Secondary Structures at Interfaces
journal, June 2011

Proteins at Interfaces Probed by Chiral Vibrational Sum Frequency Generation Spectroscopy
journal, January 2015

Lipid glycosylation: a primer for histochemists and cell biologists
journal, December 2016

C−H Stretching Vibrations of Methyl, Methylene and Methine Groups at the Vapor/Alcohol ( n = 1−8) Interfaces
journal, July 2005

Effect of Macromolecular Crowding on Protein Folding Dynamics at the Secondary Structure Level
journal, October 2009

Biological Macromolecules at Interfaces Probed by Chiral Vibrational Sum Frequency Generation Spectroscopy
journal, January 2014

Misfolding of Amyloidogenic Proteins at Membrane Surfaces: The Impact of Macromolecular Crowding
journal, December 2007

Liquid Interfaces Probed by Second-Harmonic and Sum-Frequency Spectroscopy
journal, January 1996

Heterodyne-Detected Vibrational Sum Frequency Generation Spectroscopy
journal, February 2008

Oriented secondary structure in integral membrane proteins. I. Circular dichroism and infrared spectroscopy of cytochrome oxidase in multilamellar films
journal, December 1985

Heterodyne-Detected Achiral and Chiral Vibrational Sum Frequency Generation of Proteins at Air/Water Interface
journal, April 2015

‘Zinc fingers’: a novel protein motif for nucleic acid recognition
journal, January 1987

¹⁵ N NMR Spin Relaxation Dispersion Study of the Molecular Crowding Effects on Protein Folding under Native Conditions
journal, March 2006

Chiral Vibrational Structures of Proteins at Interfaces Probed by Sum Frequency Generation Spectroscopy
journal, December 2011

Investigation of Surfactant Conformation and Order at the Liquid−Liquid Interface by Total Internal Reflection Sum-Frequency Vibrational Spectroscopy
journal, January 1996

Heterodyne-detected electronic sum frequency generation: “Up” versus “down” alignment of interfacial molecules
journal, September 2008

Specificity of lipid-protein interactions as determined by spectroscopic techniques
journal, June 1985

A Unified Treatment of Selection Rules and Symmetry Relations for Sum-Frequency and Second Harmonic Spectroscopies
journal, March 2004

Identification of the response of protein N–H vibrations in vibrational sum-frequency generation spectroscopy of aqueous protein films
journal, January 2017

Membrane bending by protein crowding is affected by protein lateral confinement
journal, June 2016

Adsorption and conformation variation of BSA protein with the size variation of the metallic nanoparticles in LB film
journal, March 2015

Making “Sense” of DNA
journal, June 2007

Chirality in Nonlinear Optics
journal, May 2009

Infrared spectroscopy of proteins and peptides in lipid bilayers
journal, November 1997

Lipid A Modification Systems in Gram-Negative Bacteria
journal, June 2007

Inhomogeneous and Spontaneous Formation of Chirality in the Langmuir Monolayer of Achiral Molecules at the Air/Water Interface Probed by In Situ Surface Second Harmonic Generation Linear Dichroism
journal, February 2009

Quantitative spectral and orientational analysis in surface sum frequency generation vibrational spectroscopy (SFG-VS)
journal, April 2005

The transmembrane domains of the nicotinic acetylcholine receptor contain alpha-helical and beta structures.
journal, January 1994

Crowding Effects of Membrane Proteins
journal, June 2009

Intrinsic Chirality and Prochirality at Air/R-(+)- and S-(-)-Limonene Interfaces: Spectral Signatures With Interference Chiral Sum-Frequency Generation Vibrational Spectroscopy: INTRINSIC CHIRALITY AND PROCHIRALITY AT AIR/R-(+)- AND S-(-)-LIMONENE INTERFACES
journal, June 2014

Broad-Bandwidth Chiral Sum Frequency Generation Spectroscopy for Probing the Kinetics of Proteins at Interfaces
journal, July 2015

Surface properties probed by second-harmonic and sum-frequency generation
journal, February 1989

Sticky water surfaces: Helix–coil transitions suppressed in a cell-penetrating peptide at the air-water interface
journal, December 2014

DPPC Langmuir Monolayer at the Air−Water Interface: Probing the Tail and Head Groups by Vibrational Sum Frequency Generation Spectroscopy
journal, June 2006

Macromolecular crowding perturbs protein refolding kinetics: implications for folding inside the cell
journal, August 2000

Amide I Two-Dimensional Infrared Spectroscopy of Proteins
journal, March 2008

Molecular Bonding and Interactions at Aqueous Surfaces as Probed by Vibrational Sum Frequency Spectroscopy
journal, August 2002

Dissociative Binding of Carboxylic Acid Ligand on Nanoceria Surface in Aqueous Solution: A Joint In Situ Spectroscopic Characterization and First-Principles Study
journal, November 2013

Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment
journal, September 2015