Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein
Abstract
In this paper, we report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology.
- Authors:
-
- Univ. of California, Los Angeles, CA (United States). UCLA-DOE Institute for Genomics and Proteomics
- Univ. of California, Los Angeles, CA (United States). UCLA-DOE Institute for Genomics and Proteomics and Department of Chemistry and Biochemistry
- Univ. of California, Los Angeles, CA (United States). Department of Chemistry and Biochemistry
- Publication Date:
- Research Org.:
- Univ. of California, Los Angeles, CA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
- OSTI Identifier:
- 1466773
- Grant/Contract Number:
- FC03-02ER63421
- Resource Type:
- Accepted Manuscript
- Journal Name:
- ChemComm
- Additional Journal Information:
- Journal Volume: 52; Journal Issue: 28; Journal ID: ISSN 1359-7345
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Jorda, J., Leibly, D. J., Thompson, M. C., and Yeates, T. O. Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein. United States: N. p., 2016.
Web. doi:10.1039/c6cc00851h.
Jorda, J., Leibly, D. J., Thompson, M. C., & Yeates, T. O. Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein. United States. doi:10.1039/c6cc00851h.
Jorda, J., Leibly, D. J., Thompson, M. C., and Yeates, T. O. Wed .
"Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein". United States. doi:10.1039/c6cc00851h. https://www.osti.gov/servlets/purl/1466773.
@article{osti_1466773,
title = {Structure of a novel 13 nm dodecahedral nanocage assembled from a redesigned bacterial microcompartment shell protein},
author = {Jorda, J. and Leibly, D. J. and Thompson, M. C. and Yeates, T. O.},
abstractNote = {In this paper, we report the crystal structure of a novel 60-subunit dodecahedral cage that results from self-assembly of a re-engineered version of a natural protein (PduA) from the Pdu microcompartment shell. Biophysical data illustrate the dependence of assembly on solution conditions, opening up new applications in microcompartment studies and nanotechnology.},
doi = {10.1039/c6cc00851h},
journal = {ChemComm},
number = 28,
volume = 52,
place = {United States},
year = {2016},
month = {3}
}
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