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Title: Experimental characterization and modeling of optical tweezer particle handling dynamics [Modeling and Simulation of Optical Tweezer Particle Handling Dynamics]

Abstract

Here, we report a new framework for a quantitative understanding of optical trapping (OT) particle handling dynamics. We present a novel three-dimensional particle-based model that includes optical, hydrodynamic, and inter-particle forces. This semi-empirical colloid model is based on an open-source simulation code known as LAMMPS (large-scale atomic/molecular massively parallel simulator) and properly recapitulates the full OT force profile beyond the typical linear approximations valid near the trap center. Simulations are carried out with typical system parameters relevant for our experimental holographic optical trapping (HOT) system, including varied particle sizes, trap movement speeds, and beam powers. Furthermore, we present a new experimental method for measuring both the stable and metastable boundaries of the optical force profile to inform or validate the model’s underlying force profile. We show that our framework is a powerful tool for accurately predicting particle behavior in a practical experimental OT setup and can be used to characterize and predict particle handling dynamics within any arbitrary OT force profile.

Authors:
 [1];  [2];  [2];  [1];  [2];  [1]
  1. Univ. of California, Los Angeles, CA (United States)
  2. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
1466135
Alternate Identifier(s):
OSTI ID: 1462149
Report Number(s):
[LLNL-JRNL-746645]
[Journal ID: ISSN 1559-128X; APOPAI; 931404]
Grant/Contract Number:  
[AC52-07NA27344; B620630; LLNL-JRNL-931404]
Resource Type:
Accepted Manuscript
Journal Name:
Applied Optics
Additional Journal Information:
[ Journal Volume: 57; Journal Issue: 22]; Journal ID: ISSN 1559-128X
Publisher:
Optical Society of America
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 42 ENGINEERING; 47 OTHER INSTRUMENTATION; 97 MATHEMATICS AND COMPUTING; optical tweezers or optical manipulation; laser trapping

Citation Formats

Porter, Michael D., Giera, Brian, Panas, Robert M., Shaw, Lucas A., Shusteff, Maxim, and Hopkins, Jonathan B. Experimental characterization and modeling of optical tweezer particle handling dynamics [Modeling and Simulation of Optical Tweezer Particle Handling Dynamics]. United States: N. p., 2018. Web. doi:10.1364/AO.57.006565.
Porter, Michael D., Giera, Brian, Panas, Robert M., Shaw, Lucas A., Shusteff, Maxim, & Hopkins, Jonathan B. Experimental characterization and modeling of optical tweezer particle handling dynamics [Modeling and Simulation of Optical Tweezer Particle Handling Dynamics]. United States. doi:10.1364/AO.57.006565.
Porter, Michael D., Giera, Brian, Panas, Robert M., Shaw, Lucas A., Shusteff, Maxim, and Hopkins, Jonathan B. Tue . "Experimental characterization and modeling of optical tweezer particle handling dynamics [Modeling and Simulation of Optical Tweezer Particle Handling Dynamics]". United States. doi:10.1364/AO.57.006565. https://www.osti.gov/servlets/purl/1466135.
@article{osti_1466135,
title = {Experimental characterization and modeling of optical tweezer particle handling dynamics [Modeling and Simulation of Optical Tweezer Particle Handling Dynamics]},
author = {Porter, Michael D. and Giera, Brian and Panas, Robert M. and Shaw, Lucas A. and Shusteff, Maxim and Hopkins, Jonathan B.},
abstractNote = {Here, we report a new framework for a quantitative understanding of optical trapping (OT) particle handling dynamics. We present a novel three-dimensional particle-based model that includes optical, hydrodynamic, and inter-particle forces. This semi-empirical colloid model is based on an open-source simulation code known as LAMMPS (large-scale atomic/molecular massively parallel simulator) and properly recapitulates the full OT force profile beyond the typical linear approximations valid near the trap center. Simulations are carried out with typical system parameters relevant for our experimental holographic optical trapping (HOT) system, including varied particle sizes, trap movement speeds, and beam powers. Furthermore, we present a new experimental method for measuring both the stable and metastable boundaries of the optical force profile to inform or validate the model’s underlying force profile. We show that our framework is a powerful tool for accurately predicting particle behavior in a practical experimental OT setup and can be used to characterize and predict particle handling dynamics within any arbitrary OT force profile.},
doi = {10.1364/AO.57.006565},
journal = {Applied Optics},
number = [22],
volume = [57],
place = {United States},
year = {2018},
month = {7}
}

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