skip to main content

DOE PAGESDOE PAGES

Title: Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells

Miniaturized multidimensional peptide separations can greatly increase the coverage in proteome profiling for trace samples.
Authors:
ORCiD logo [1] ; ORCiD logo [1] ;  [1] ;  [1] ;  [2] ;  [1] ;  [1] ;  [1] ;  [1] ;  [2] ;  [2] ; ORCiD logo [1] ; ORCiD logo [1]
  1. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  2. Univ. of Florida, Gainesville, FL (United States)
Publication Date:
Report Number(s):
PNNL-SA-133217
Journal ID: ISSN 2041-6520
Grant/Contract Number:
DP3DK110844; UC4DK104167; R33CA225248; R21EB020976; AC05-76RL01830
Type:
Accepted Manuscript
Journal Name:
Chemical Science
Additional Journal Information:
Journal Volume: 9; Journal Issue: 34; Journal ID: ISSN 2041-6520
Publisher:
Royal Society of Chemistry
Research Org:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES
OSTI Identifier:
1461650

Dou, Maowei, Zhu, Ying, Liyu, Andrey, Liang, Yiran, Chen, Jing, Piehowski, Paul D., Xu, Kerui, Zhao, Rui, Moore, Ronald J., Atkinson, Mark A., Mathews, Clayton E., Qian, Wei -Jun, and Kelly, Ryan T.. Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells. United States: N. p., Web. doi:10.1039/C8SC02680G.
Dou, Maowei, Zhu, Ying, Liyu, Andrey, Liang, Yiran, Chen, Jing, Piehowski, Paul D., Xu, Kerui, Zhao, Rui, Moore, Ronald J., Atkinson, Mark A., Mathews, Clayton E., Qian, Wei -Jun, & Kelly, Ryan T.. Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells. United States. doi:10.1039/C8SC02680G.
Dou, Maowei, Zhu, Ying, Liyu, Andrey, Liang, Yiran, Chen, Jing, Piehowski, Paul D., Xu, Kerui, Zhao, Rui, Moore, Ronald J., Atkinson, Mark A., Mathews, Clayton E., Qian, Wei -Jun, and Kelly, Ryan T.. 2018. "Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells". United States. doi:10.1039/C8SC02680G. https://www.osti.gov/servlets/purl/1461650.
@article{osti_1461650,
title = {Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells},
author = {Dou, Maowei and Zhu, Ying and Liyu, Andrey and Liang, Yiran and Chen, Jing and Piehowski, Paul D. and Xu, Kerui and Zhao, Rui and Moore, Ronald J. and Atkinson, Mark A. and Mathews, Clayton E. and Qian, Wei -Jun and Kelly, Ryan T.},
abstractNote = {Miniaturized multidimensional peptide separations can greatly increase the coverage in proteome profiling for trace samples.},
doi = {10.1039/C8SC02680G},
journal = {Chemical Science},
number = 34,
volume = 9,
place = {United States},
year = {2018},
month = {7}
}