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Title: Excitation functions for (p,x) reactions of niobium in the energy range of Ep = 40–90 MeV

Abstract

In this paper, a stack of thin Nb foils was irradiated with the 100 MeV proton beam at Los Alamos National Laboratory’s Isotope Production Facility, to investigate the 93Nb(p,4n)90Mo nuclear reaction as a monitor for intermediate energy proton experiments and to benchmark state-of-the-art reaction model codes. A set of 38 measured cross sections for natNb(p,x) and natCu(p,x) reactions between 40–90 MeV, as well as 5 independent measurements of isomer branching ratios, are reported. These are useful in medical and basic science radionuclide productions at intermediate energies. The natCu(p,x)56Co, natCu(p,x)62Zn, and natCu(p,x)65Zn reactions were used to determine proton fluence, and all activities were quantified using HPGe spectrometry. Variance minimization techniques were employed to reduce systematic uncertainties in proton energy and fluence, improving the reliability of these measurements. The measured cross sections are shown to be in excellent agreement with literature values, and have been measured with improved precision compared with previous measurements. This work also reports the first measurement of the natNb(p,x)82mRb reaction, and of the independent cross sections for natCu(p,x)52gMn and natNb(p,x)85gY in the 40–90 MeV region. The effects of natSi(p,x)22,24Na contamination, arising from silicone adhesive in the Kapton tape used to encapsulate the aluminum monitor foils, is also discussedmore » as a cautionary note to future stacked-target cross section measurements. Finally, a priori predictions of the reaction modeling codes CoH, EMPIRE, and TALYS are compared with experimentally measured values and used to explore the differences between codes for the natNb(p,x) and natCu(p,x) reactions.« less

Authors:
 [1];  [2];  [3];  [4];  [5];  [3];  [1];  [3]
  1. Univ. of California, Berkeley, CA (United States). Dept. of Nuclear Engineering
  2. Univ. of California, Berkeley, CA (United States). Dept. of Nuclear Engineering; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Nuclear Science Division
  3. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  4. Univ. of Wisconsin, Madison, WI (United States). Dept. of Medical Physics
  5. Univ. of Iowa, Iowa City, IA (United States). Dept. of Radiation Oncology
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Nuclear Physics (NP); USDOE National Nuclear Security Administration (NNSA), Office of Naval Reactors; Nuclear Regulatory Commission (NRC) (United States)
OSTI Identifier:
1459841
Alternate Identifier(s):
OSTI ID: 1528901; OSTI ID: 1582958
Report Number(s):
LA-UR-18-22980
Journal ID: ISSN 0168-583X; TRN: US1901814
Grant/Contract Number:  
AC52-06NA25396; AC02-05CH11231
Resource Type:
Accepted Manuscript
Journal Name:
Nuclear Instruments and Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms
Additional Journal Information:
Journal Volume: 429; Journal ID: ISSN 0168-583X
Publisher:
Elsevier
Country of Publication:
United States
Language:
English
Subject:
73 NUCLEAR PHYSICS AND RADIATION PHYSICS; Nb + p; Cu + p; niobium; 90Mo; nuclear cross sections; stacked target activation; monitor reactions; medical isotope production; isomer branching ratios; MCNP; LANL

Citation Formats

Voyles, Andrew S., Bernstein, Lee A., Birnbaum, Eva R., Engle, Jonathan W., Graves, Stephen A., Kawano, Toshihiko, Lewis, Amanda M., and Nortier, Francois M. Excitation functions for (p,x) reactions of niobium in the energy range of Ep = 40–90 MeV. United States: N. p., 2018. Web. doi:10.1016/j.nimb.2018.05.028.
Voyles, Andrew S., Bernstein, Lee A., Birnbaum, Eva R., Engle, Jonathan W., Graves, Stephen A., Kawano, Toshihiko, Lewis, Amanda M., & Nortier, Francois M. Excitation functions for (p,x) reactions of niobium in the energy range of Ep = 40–90 MeV. United States. https://doi.org/10.1016/j.nimb.2018.05.028
Voyles, Andrew S., Bernstein, Lee A., Birnbaum, Eva R., Engle, Jonathan W., Graves, Stephen A., Kawano, Toshihiko, Lewis, Amanda M., and Nortier, Francois M. Fri . "Excitation functions for (p,x) reactions of niobium in the energy range of Ep = 40–90 MeV". United States. https://doi.org/10.1016/j.nimb.2018.05.028. https://www.osti.gov/servlets/purl/1459841.
@article{osti_1459841,
title = {Excitation functions for (p,x) reactions of niobium in the energy range of Ep = 40–90 MeV},
author = {Voyles, Andrew S. and Bernstein, Lee A. and Birnbaum, Eva R. and Engle, Jonathan W. and Graves, Stephen A. and Kawano, Toshihiko and Lewis, Amanda M. and Nortier, Francois M.},
abstractNote = {In this paper, a stack of thin Nb foils was irradiated with the 100 MeV proton beam at Los Alamos National Laboratory’s Isotope Production Facility, to investigate the 93Nb(p,4n)90Mo nuclear reaction as a monitor for intermediate energy proton experiments and to benchmark state-of-the-art reaction model codes. A set of 38 measured cross sections for natNb(p,x) and natCu(p,x) reactions between 40–90 MeV, as well as 5 independent measurements of isomer branching ratios, are reported. These are useful in medical and basic science radionuclide productions at intermediate energies. The natCu(p,x)56Co, natCu(p,x)62Zn, and natCu(p,x)65Zn reactions were used to determine proton fluence, and all activities were quantified using HPGe spectrometry. Variance minimization techniques were employed to reduce systematic uncertainties in proton energy and fluence, improving the reliability of these measurements. The measured cross sections are shown to be in excellent agreement with literature values, and have been measured with improved precision compared with previous measurements. This work also reports the first measurement of the natNb(p,x)82mRb reaction, and of the independent cross sections for natCu(p,x)52gMn and natNb(p,x)85gY in the 40–90 MeV region. The effects of natSi(p,x)22,24Na contamination, arising from silicone adhesive in the Kapton tape used to encapsulate the aluminum monitor foils, is also discussed as a cautionary note to future stacked-target cross section measurements. Finally, a priori predictions of the reaction modeling codes CoH, EMPIRE, and TALYS are compared with experimentally measured values and used to explore the differences between codes for the natNb(p,x) and natCu(p,x) reactions.},
doi = {10.1016/j.nimb.2018.05.028},
journal = {Nuclear Instruments and Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms},
number = ,
volume = 429,
place = {United States},
year = {2018},
month = {6}
}

Works referenced in this record:

Status of and Trends in Nuclear Medicine in the United States
journal, December 2011


Nuclear Data Sheets for A = 48
journal, July 2006


Nuclear Data Sheets for A = 90
journal, November 1997


Pre-equilibrium emission effects in the measured isomeric yield ratios in alpha-induced reactions on Au 197
journal, March 1992


Nuclear Data Sheets for A = 52
journal, September 2015


Nuclear Data Sheets for A = 58
journal, April 2010

  • Nesaraja, Caroline D.; Geraedts, Scott D.; Singh, Balraj
  • Nuclear Data Sheets, Vol. 111, Issue 4
  • DOI: 10.1016/j.nds.2010.03.003

Nuclear Data Sheets for
journal, February 2014


Nuclear Data Sheets for A = 87
journal, November 2015


Nuclear Data Sheets for A = 89
journal, January 2013


Nuclear excitation functions of proton-induced reactions (Ep= 35–90 MeV) from Fe, Cu, and Al
journal, November 2016

  • Graves, Stephen A.; Ellison, Paul A.; Barnhart, Todd E.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 386
  • DOI: 10.1016/j.nimb.2016.09.018

Monitor Reactions for High Energy Proton Beams
journal, December 1963


Synthetic spectra for radioactive strontium production QA/QC
journal, April 2014

  • Jackman, K. R.; Engle, J. W.; Nortier, F. M.
  • Journal of Radioanalytical and Nuclear Chemistry, Vol. 302, Issue 1
  • DOI: 10.1007/s10967-014-3138-6

General solution of Bateman equations for nuclear transmutations
journal, May 2006


Production of 52Fe via proton-induced reactions on manganese and nickel
journal, January 1990

  • Steyn, G. F.; Mills, S. J.; Nortier, F. M.
  • International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 41, Issue 3
  • DOI: 10.1016/0883-2889(90)90197-O

Experimental studies on the proton-induced activation reactions of molybdenum in the energy range 22–67MeV
journal, June 2004


Experimental and theoretical excitation functions of radionuclides produced in proton bombardment of copper up to 200 MeV
journal, August 1992

  • Mills, S. J.; Steyn, G. F.; Nortier, F. M.
  • International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 43, Issue 8
  • DOI: 10.1016/0883-2889(92)90221-Y

Stopping of energetic light ions in elemental matter
journal, February 1999

  • Ziegler, J. F.
  • Journal of Applied Physics, Vol. 85, Issue 3
  • DOI: 10.1063/1.369844

Initial MCNP6 Release Overview
journal, December 2012

  • Goorley, T.; James, M.; Booth, T.
  • Nuclear Technology, Vol. 180, Issue 3
  • DOI: 10.13182/NT11-135

Experimental and computational techniques for the analysis of proton beam propagation through a target stack
journal, February 2015

  • Marus, L. A.; Engle, J. W.; John, K. D.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 345
  • DOI: 10.1016/j.nimb.2014.12.048

Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer
journal, July 2015

  • Gourni, Eleni; Del Pozzo, Luigi; Kheirallah, Emilie
  • Molecular Pharmaceutics, Vol. 12, Issue 8
  • DOI: 10.1021/mp500671j

Investigation of the 66Zn(p,2pn)64Cu and 68Zn(p,x)64Cu nuclear processes up to 100 MeV: Production of 64Cu
journal, November 2005

  • Szelecsényi, F.; Steyn, G. F.; Kovács, Z.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 240, Issue 3
  • DOI: 10.1016/j.nimb.2005.05.057

Measurement of the 64Zn,47Ti(n,p) cross sections using a DD neutron generator for medical isotope studies
journal, November 2017

  • Voyles, A. S.; Basunia, M. S.; Batchelder, J. C.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 410
  • DOI: 10.1016/j.nimb.2017.08.021

Simplified and reproducible radiochemical separations for the production of high specific activity 61Cu, 64Cu, 86Y and 55Co
conference, January 2017

  • Valdovinos, Hector F.; Graves, Stephen; Barnhart, Todd
  • WTTC16: Proceedings of the 16th International Workshop on Targetry and Target Chemistry, AIP Conference Proceedings
  • DOI: 10.1063/1.4983552

The production of a broader palette of PET tracers
journal, January 2003

  • Nickles, R. J.
  • Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 46, Issue 1
  • DOI: 10.1002/jlcr.639

Production of the positron emitting radioisotope 86Y for nuclear medical application
journal, April 1993


Reactions of 88 Sr with protons of energies7–85 MeV
journal, May 1967

  • Sachdev, D. R.; Porile, N. T.; Yaffe, L.
  • Canadian Journal of Chemistry, Vol. 45, Issue 10
  • DOI: 10.1139/v67-193

Development and Characterization of Clinical-Grade 89 Zr-Trastuzumab for HER2/ neu ImmunoPET Imaging
journal, May 2009

  • Dijkers, Eli C. F.; Kosterink, Jos G. W.; Rademaker, Anna P.
  • Journal of Nuclear Medicine, Vol. 50, Issue 6
  • DOI: 10.2967/jnumed.108.060392

Biodistribution of 89Zr-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer
journal, March 2010

  • Dijkers, E. C.; Oude Munnink, T. H.; Kosterink, J. G.
  • Clinical Pharmacology & Therapeutics, Vol. 87, Issue 5
  • DOI: 10.1038/clpt.2010.12

Proton induced reactions on 89Y with particular reference to the production of the medically interesting radionuclide 89Zr
journal, January 2009


Cross section data for the production of the positron emitting niobium isotope 90 Nb via the 90 Zr( p , n )-reaction
journal, January 2002


90 Nb – a potential PET nuclide: production and labeling of monoclonal antibodies
journal, April 2012


Production of 6.5 h 82mRb via the 82Kr(p, n)-process at a low-energy cyclotron—A potential substitute for 82Rb
journal, January 1991

  • Kovács, Z.; Tárkányi, F.; Qaim, S. M.
  • International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 42, Issue 9
  • DOI: 10.1016/0883-2889(91)90220-U

Measurement and simulation of the cross sections for nuclide production in 93Nb and natNi targets irradiated with 0.04- to 2.6-GeV protons
journal, April 2011

  • Titarenko, Yu. E.; Batyaev, V. F.; Titarenko, A. Yu.
  • Physics of Atomic Nuclei, Vol. 74, Issue 4
  • DOI: 10.1134/S106377881104017X

Nuclear Data Sheets for A = 57
journal, November 1998


Cross sections for the production of residual nuclides by low- and medium-energy protons from the target elements C, N, O, Mg, Al, Si, Ca, Ti, V, Mn, Fe, Co, Ni, Cu, Sr, Y, Zr, Nb, Ba and Au
journal, July 1997

  • Michel, R.; Bodemann, R.; Busemann, H.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 129, Issue 2
  • DOI: 10.1016/S0168-583X(97)00213-9

Activation cross-sections of longer lived products of proton induced nuclear reactions on cobalt up to 70 MeV
journal, June 2013

  • Ditrói, F.; Tárkányi, F.; Takács, S.
  • Journal of Radioanalytical and Nuclear Chemistry, Vol. 298, Issue 2
  • DOI: 10.1007/s10967-013-2578-8

RIPL – Reference Input Parameter Library for Calculation of Nuclear Reactions and Nuclear Data Evaluations
journal, December 2009


EMPIRE: Nuclear Reaction Model Code System for Data Evaluation
journal, December 2007


Local and global nucleon optical models from 1 keV to 200 MeV
journal, January 2003


Complementary optical-potential analysis of -particle elastic scattering and induced reactions at low energies
journal, July 2009

  • Avrigeanu, M.; Obreja, A. C.; Roman, F. L.
  • Atomic Data and Nuclear Data Tables, Vol. 95, Issue 4
  • DOI: 10.1016/j.adt.2009.02.001

Modern Nuclear Data Evaluation with the TALYS Code System
journal, December 2012


Monte Carlo Simulation for Particle and γ-Ray Emissions in Statistical Hauser-Feshbach Model
journal, May 2010

  • Kawano, Toshihiko; Talou, Patrick; Chadwick, Mark B.
  • Journal of Nuclear Science and Technology, Vol. 47, Issue 5
  • DOI: 10.1080/18811248.2010.9711637

Global optical potentials for emitted alpha particles
journal, April 1994


Nuclear Data Sheets for A = 22
journal, July 2015


Nuclear Data Sheets for A = 24
journal, November 2007


Nuclear Data Sheets for A = 51
journal, September 2017


Nuclear Data Sheets for A = 54
journal, September 2014


Nuclear Data Sheets for A = 55
journal, April 2008


Nuclear Data Sheets for A = 56
journal, June 2011


Nuclear Data Sheets for A = 59
journal, February 2002


Nuclear Data Sheets for A = 60
journal, December 2013


Nuclear Data Sheets for A = 61
journal, March 2015


Nuclear Data Sheets for A = 62
journal, April 2012


Nuclear Data Sheets for A = 64
journal, February 2007


Nuclear Data Sheets for A = 65
journal, September 2010


Nuclear Data Sheets for A = 82
journal, February 2003


Nuclear Data Sheets for A = 83
journal, March 2015


Nuclear Data Sheets for A = 86
journal, February 2015


Nuclear Data Sheets for A = 88
journal, January 2014


Nuclear Data Sheets for A = 91
journal, October 2013


Nuclear Data Sheets for A = 92
journal, October 2012


Nuclear Data Sheets for A = 93
journal, May 2011


Réactions (p, 3p3n) entre 30 et 150 MeV
journal, January 1963


Excitation Functions for Radioactive Isotopes Produced by Protons below 60 MeV on Al, Fe, and Cu
journal, October 1967


Thin-Target Cross Sections for Some Cr, Mn, Fe, Co, Ni, and Zn Nuclides Produced in Copper by 82- to 416-MeV Protons
journal, October 1972

  • Heydegger, H. R.; Garrett, C. K.; Van Ginneken, A.
  • Physical Review C, Vol. 6, Issue 4
  • DOI: 10.1103/PhysRevC.6.1235

Production cross section of radionuclides in (p, x) reactions at copper and nickel nuclei
journal, June 1987

  • Aleksandrov, V. N.; Semenova, M. P.; Semenov, V. G.
  • Soviet Atomic Energy, Vol. 62, Issue 6
  • DOI: 10.1007/BF01124118

Excitation functions of proton induced nuclear reactions on natRb from 30 to 70 MeV. Implication for the production of 82Sr and other medically important Rb and Sr radioisotopes
journal, October 2002

  • Ido, Tatsuo; Hermanne, Alex; Ditrói, Ferenc
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 194, Issue 4
  • DOI: 10.1016/S0168-583X(02)00958-8

Measurement and calculation of radioactivities of spallation products by high-energy heavy ions
journal, December 2003


Excitation functions of proton induced nuclear reactions on natural copper using a medium-sized cyclotron
journal, January 2006


Study of proton induced reactions on niobium targets up to 70MeV
journal, December 2008

  • Ditrói, F.; Takács, S.; Tárkányi, F.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 266, Issue 24
  • DOI: 10.1016/j.nimb.2008.09.023

Investigation of proton induced reactions on niobium at low and medium energies
journal, October 2009

  • Ditrói, F.; Hermanne, A.; Corniani, E.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 267, Issue 19
  • DOI: 10.1016/j.nimb.2009.07.010

Excitation Functions of Proton Induced Reactions on 89Y and 93Nb with Emphasis on the Production of Selected Radio-Zirconiums
journal, August 2011

  • Steyn, G. F.; Vermeulen, C.; Szelecsenyi, F.
  • Journal of the Korean Physical Society, Vol. 59, Issue 2(3)
  • DOI: 10.3938/jkps.59.1991

Measurement of excitation functions in proton induced reactions on natural copper from their threshold to 43MeV
journal, January 2015

  • Shahid, Muhammad; Kim, Kwangsoo; Naik, Haladhara
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 342
  • DOI: 10.1016/j.nimb.2014.10.019

New excitation functions for proton induced reactions on natural titanium, nickel and copper up to 70 MeV
journal, September 2016

  • Garrido, E.; Duchemin, C.; Guertin, A.
  • Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 383
  • DOI: 10.1016/j.nimb.2016.07.011