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Title: Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians

Abstract

Recent outbreaks of chytridiomycosis, the disease of amphibians caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd), have contributed to population declines of numerous amphibian species worldwide. The devastating impacts of this disease have led researchers to attempt drastic conservation measures to prevent further extinctions and loss of biodiversity. The conservation measures can be labour-intensive or expensive, and in many cases have been unsuccessful. We developed a mathematical model of Bd outbreaks that includes the effects of demographic stochasticity and within-host fungal load dynamics. We investigated the impacts of onetime treatment conservation strategies during the disease outbreak that occurs following the initial arrival of Bd into a previously uninfected frog population. We found that for all versions of the model, for a large fraction of parameter space, none of the one-time treatment strategies are effective at preventing disease-induced extinction of the amphibian population. Of the strategies considered, treating frogs with antifungal agents to reduce their fungal load had the greatest likelihood of a beneficial outcome and the lowest risk of decreasing the persistence of the frog population, suggesting that this disease mitigation strategy should be prioritized over disinfecting the environment or reducing host density.

Authors:
ORCiD logo [1];  [2];  [3];  [3]
  1. Univ. of North Carolina, Ashville, NC (United States)
  2. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
  3. Univ. of California, Santa Barbara, CA (United States)
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
1458654
Report Number(s):
LLNL-JRNL-741278
Journal ID: ISSN 1742-5689; 895299
Grant/Contract Number:  
AC52-07NA27344
Resource Type:
Accepted Manuscript
Journal Name:
Journal of the Royal Society Interface
Additional Journal Information:
Journal Volume: 14; Journal Issue: 133; Journal ID: ISSN 1742-5689
Publisher:
The Royal Society
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Drawert, Brian, Griesemer, Marc, Petzold, Linda R., and Briggs, Cheryl J. Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians. United States: N. p., 2017. Web. doi:10.1098/rsif.2017.0480.
Drawert, Brian, Griesemer, Marc, Petzold, Linda R., & Briggs, Cheryl J. Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians. United States. doi:10.1098/rsif.2017.0480.
Drawert, Brian, Griesemer, Marc, Petzold, Linda R., and Briggs, Cheryl J. Wed . "Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians". United States. doi:10.1098/rsif.2017.0480. https://www.osti.gov/servlets/purl/1458654.
@article{osti_1458654,
title = {Using stochastic epidemiological models to evaluate conservation strategies for endangered amphibians},
author = {Drawert, Brian and Griesemer, Marc and Petzold, Linda R. and Briggs, Cheryl J.},
abstractNote = {Recent outbreaks of chytridiomycosis, the disease of amphibians caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd), have contributed to population declines of numerous amphibian species worldwide. The devastating impacts of this disease have led researchers to attempt drastic conservation measures to prevent further extinctions and loss of biodiversity. The conservation measures can be labour-intensive or expensive, and in many cases have been unsuccessful. We developed a mathematical model of Bd outbreaks that includes the effects of demographic stochasticity and within-host fungal load dynamics. We investigated the impacts of onetime treatment conservation strategies during the disease outbreak that occurs following the initial arrival of Bd into a previously uninfected frog population. We found that for all versions of the model, for a large fraction of parameter space, none of the one-time treatment strategies are effective at preventing disease-induced extinction of the amphibian population. Of the strategies considered, treating frogs with antifungal agents to reduce their fungal load had the greatest likelihood of a beneficial outcome and the lowest risk of decreasing the persistence of the frog population, suggesting that this disease mitigation strategy should be prioritized over disinfecting the environment or reducing host density.},
doi = {10.1098/rsif.2017.0480},
journal = {Journal of the Royal Society Interface},
number = 133,
volume = 14,
place = {United States},
year = {2017},
month = {8}
}

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    Works referencing / citing this record:

    Emerging infectious diseases and biological invasions: a call for a One Health collaboration in science and management
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    • Ogden, Nick H.; Wilson, John R. U.; Richardson, David M.
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    Emerging infectious diseases and biological invasions: a call for a One Health collaboration in science and management
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