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Title: Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp 3 C–H) with indoles (sp 2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp 3 C–H) with indoles (sp 2 C–H)]

Abstract

Here, we disclose a novel, heterogeneous catalytic approach for selective coupling of C1 of N-aryltetrahydroisoquinolines with C3 of indoles in the presence of mesoporous manganese oxides. Our work involves a detailed mechanistic investigation of the reaction on the catalyst surface, backed by DFT computational studies, to understand the superior catalytic activity of manganese oxides.

Authors:
 [1]; ORCiD logo [2];  [1];  [1];  [1];  [1];  [1];  [1]; ORCiD logo [1]
  1. Univ. of Connecticut, Storrs, CT (United States)
  2. Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1456820
Grant/Contract Number:  
[AC05-00OR22725]
Resource Type:
Accepted Manuscript
Journal Name:
Green Chemistry
Additional Journal Information:
[ Journal Volume: 19; Journal Issue: 22]; Journal ID: ISSN 1463-9262
Publisher:
Royal Society of Chemistry
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Dutta, B., Sharma, Vinit K., Sassu, N., Dang, Y., Weerakkody, C., Macharia, J., Miao, R., Howell, A. R., and Suib, Steven L. Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]. United States: N. p., 2017. Web. doi:10.1039/C7GC01919J.
Dutta, B., Sharma, Vinit K., Sassu, N., Dang, Y., Weerakkody, C., Macharia, J., Miao, R., Howell, A. R., & Suib, Steven L. Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]. United States. doi:10.1039/C7GC01919J.
Dutta, B., Sharma, Vinit K., Sassu, N., Dang, Y., Weerakkody, C., Macharia, J., Miao, R., Howell, A. R., and Suib, Steven L. Wed . "Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]". United States. doi:10.1039/C7GC01919J. https://www.osti.gov/servlets/purl/1456820.
@article{osti_1456820,
title = {Cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H) using a heterogeneous mesoporous manganese oxide catalyst [Mesoporous manganese oxide catalyzed cross dehydrogenative coupling of N-aryltetrahydroisoquinolines (sp3 C–H) with indoles (sp2 C–H)]},
author = {Dutta, B. and Sharma, Vinit K. and Sassu, N. and Dang, Y. and Weerakkody, C. and Macharia, J. and Miao, R. and Howell, A. R. and Suib, Steven L.},
abstractNote = {Here, we disclose a novel, heterogeneous catalytic approach for selective coupling of C1 of N-aryltetrahydroisoquinolines with C3 of indoles in the presence of mesoporous manganese oxides. Our work involves a detailed mechanistic investigation of the reaction on the catalyst surface, backed by DFT computational studies, to understand the superior catalytic activity of manganese oxides.},
doi = {10.1039/C7GC01919J},
journal = {Green Chemistry},
number = [22],
volume = [19],
place = {United States},
year = {2017},
month = {9}
}

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