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This content will become publicly available on June 6, 2019

Title: Structure and properties of DOTA-chelated radiopharmaceuticals within the 225 Ac decay pathway

The stability of DOTA-chelated complexes coordinated with H 2 O has a strong correlation between the opening angle of DOTA and the atomic mass of the radioactive isotope.
Authors:
 [1] ;  [2] ; ORCiD logo [3] ;  [4] ; ORCiD logo [5] ; ORCiD logo [1]
  1. Department of Physics, University of South Florida, Tampa, USA
  2. Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA
  3. Small Animal Imaging Laboratory Shared Resource, H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA
  4. Department of Pharmaceutical Sciences, West Virginia University, Health Sciences Center, Morgantown, USA
  5. Department of Cancer Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA, Department of Oncologic Sciences
Publication Date:
Grant/Contract Number:
DE FG02-06ER46297
Type:
Publisher's Accepted Manuscript
Journal Name:
MedChemComm
Additional Journal Information:
Journal Name: MedChemComm Journal Volume: 9 Journal Issue: 7; Journal ID: ISSN 2040-2503
Publisher:
Royal Society of Chemistry (RSC)
Sponsoring Org:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
Country of Publication:
United Kingdom
Language:
English
OSTI Identifier:
1454630