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Title: Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design

Authors:
 [1] ;  [2] ; ORCiD logo [3] ;  [4] ; ORCiD logo [5] ; ORCiD logo [2] ;  [6] ;  [7] ; ORCiD logo [1]
  1. Department of Biochemistry &, Structural Biology, Lund University, S-221 00 Lund, Sweden
  2. Department of Biophysical Chemistry, Lund University, S-221 00 Lund, Sweden
  3. Jülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ), Forschungszentrum Jülich GmbH, Lichtenbergstrasse 1, 85747 Garching, Germany
  4. Heinz Maier-Leibnitz Zentrum (MLZ), Technische Universität München, Lichtenbergstrasse 1, 85748 Garching, Germany
  5. Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States
  6. Institut Laue-Langevin, 71 avenue des Martyrs, 38000 Grenoble, France
  7. Department of Biochemistry &, Structural Biology, Lund University, S-221 00 Lund, Sweden, Instrument Division, European Spallation Source ERIC, Box 176, S-221 00 Lund, Sweden
Publication Date:
Type:
Published Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Volume: 61; Journal Issue: 10; Related Information: CHORUS Timestamp: 2018-05-24 13:30:16; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society
Sponsoring Org:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
Country of Publication:
United States
Language:
English
OSTI Identifier:
1438966