T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers

Drobna, Monika; Szarzyńska-Zawadzka, Bronisława; Dawidowska, Małgorzata

doi:10.1016/j.blre.2018.04.003

Title: T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers

Full Record
Other Related Research

Authors:

; Szarzyńska-Zawadzka, Bronisława;

Publication Date:: 2018-11-01

Sponsoring Org.:: USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research

OSTI Identifier:: 1437865

Grant/Contract Number:: STRATEGMED3/304586/5/NCBR/2017

Resource Type:: Published Article

Journal Name:: Blood Reviews

Additional Journal Information:: Journal Name: Blood Reviews Journal Volume: 32 Journal Issue: 6; Journal ID: ISSN 0268-960X

Publisher:: Elsevier

Country of Publication:: Country unknown/Code not available

Language:: English

Citation Formats


                    Drobna, Monika, Szarzyńska-Zawadzka, Bronisława, and Dawidowska, Małgorzata. T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers.  Country unknown/Code not available: N. p., 2018. 
Web.  doi:10.1016/j.blre.2018.04.003.

Copy to clipboard


                    Drobna, Monika, Szarzyńska-Zawadzka, Bronisława, & Dawidowska, Małgorzata. T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers.  Country unknown/Code not available.  https://doi.org/10.1016/j.blre.2018.04.003

Copy to clipboard


                    Drobna, Monika, Szarzyńska-Zawadzka, Bronisława, and Dawidowska, Małgorzata. Thu .  
"T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers".  Country unknown/Code not available.  https://doi.org/10.1016/j.blre.2018.04.003.

Copy to clipboard


                    
@article{osti_1437865,

  title        = {T-cell acute lymphoblastic leukemia from miRNA perspective: Basic concepts, experimental approaches, and potential biomarkers},

  author       = {Drobna, Monika and Szarzyńska-Zawadzka, Bronisława and Dawidowska, Małgorzata},

  abstractNote = {},

  doi          = {10.1016/j.blre.2018.04.003},

  journal      = {Blood Reviews},

  number       = 6,

  volume       = 32,

  place        = {Country unknown/Code not available},

  year         = {2018},

  month        = {11}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Publisher's Version of Record
https://doi.org/10.1016/j.blre.2018.04.003

Other availability

Search WorldCat to find libraries that may hold this journal

Citation Metrics:

Cited by: 6 works

Citation information provided by
Web of Science

Save / Share:

Export Metadata

Save to My Library

Similar Records in DOE PAGES and OSTI.GOV collections:

CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells

Journal Article Yamazaki, Hiroto ; Nishida, Hiroko ; Iwata, Satoshi ; ... - Biochemical and Biophysical Research Communications

Although cancer stem cells (CSCs) have been recently identified in myeloid leukemia, published data on lymphoid malignancy have been sparse. T-acute lymphoblastic leukemia (T-ALL) is characterized by the abnormal proliferation of T-cell precursors and is generally aggressive. As CD34 is the only positive-selection marker for CSCs in T-ALL, we performed extensive analysis of CD markers in T-ALL cell lines. We found that some of the tested lines consisted of heterogeneous populations of cells with various levels of surface marker expression. In particular, a small subpopulation of CD90 (Thy-1) and CD110 (c-Mpl) were shown to correlate with stem cell properties bothmore »« less
https://doi.org/10.1016/J.BBRC.2009.03.127
Profound radiosensitivity in leukemic T-cell lines and T-cell-type acute lymphoblastic leukemia demonstrated by sodium (51Cr)chromate labeling

Journal Article Nakazawa, S ; Minowada, J ; Tsubota, T ; ... - Cancer Res.; (United States)

Radiation sensitivity was determined by measuring spontaneous release from /sup 51/Cr-labeled cells in various lymphoid cell populations. Among six leukemia T-cell lines originating from acute lymphoblastic leukemia, four such lines were found to be highly radiosensitive. In contrast, two of the leukemic T-cell lines and four normal control B-cell lines were not radiosensitive. Thymocytes from six patients and leukemia T-cell blasts from three patients with T-cell leukemia were likewise found to be highly radiosensitive, whereas leukemic blasts from six patients with null-cell (non-T, non-B-cell) acute lymphoblastic leukemia were not radiosensitive. Normal peripheral blood lymphocytes and mitogen-induced normal lymphoblasts were foundmore »« less
A novel 2,6-diisopropylphenyl-docosahexaenoamide conjugate induces apoptosis in T cell acute lymphoblastic leukemia cell lines

Journal Article Altenburg, Jeffrey D. ; Harvey, Kevin A. ; McCray, Sharon ; ... - Biochemical and Biophysical Research Communications

Highlights: {yields} 2,6-Diisopropylphenyl-docosahexaenoamide conjugates (DIP-DHA) inhibits the proliferation of T-cell leukemic cell lines. {yields} DIP-DHA resulted in increased activation of caspase-3, and caspase-7. {yields} DIP-DHA significantly downregulated CXCR4 surface expression. -- Abstract: We have previously characterized the effects of 2,6-diisopropylphenyl-docosahexaenoamide (DIP-DHA) conjugates and their analogs on the proliferation and progression of breast cancer cell lines. For this study, we investigated the effects of the DIP-DHA conjugate on 2 representative T cell acute lymphoblastic leukemia (T-ALL) cell lines: CEM and Jurkat. Treatment of both cell lines with DIP-DHA resulted in significantly greater inhibition of proliferation and induction of apoptosis than thatmore »« less
https://doi.org/10.1016/J.BBRC.2011.06.172
Plumbagin exerts an immunosuppressive effect on human T-cell acute lymphoblastic leukemia MOLT-4 cells

Journal Article Bae, Kyoung Jun ; Lee, Yura ; Kim, Soon Ae ; ... - Biochemical and Biophysical Research Communications

Of the hematological disorders typified by poor prognoses and survival rates, T-cell acute lymphoblastic leukemia (T-ALL) is one of the most commonly diagnosed. Despite the development of new therapeutic agents, the treatment options for this cancer remain limited. In this manuscript, we investigated the anti-proliferative effects of plumbagin, mediated by the activation of mitogen-activated protein kinase (MAPK) pathways, and inhibition of NF-κB signaling; the human T-ALL MOLT-4 cell line was used as our experimental system. Plumbagin is a natural, plant derived compound, which exerts an anti-proliferative activity against many types of human cancer. Our experiments confirm that plumbagin induces a caspase-dependentmore »« less
https://doi.org/10.1016/J.BBRC.2016.03.092
Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines

Journal Article Ooko, Edna ; Alsalim, Tahseen ; Saeed, Bahjat ; ... - Toxicology and Applied Pharmacology

Background: Multidrug resistance (MDR) and drug transporter P-glycoprotein (P-gp) represent major obstacles in cancer chemotherapy. We investigated 19 synthetic curcumin derivatives in drug-sensitive acute lymphoblastic CCRF–CEM leukemia cells and their multidrug-resistant P-gp-overexpressing subline, CEM/ADR5000. Material and methods: Cytotoxicity was tested by resazurin assays. Doxorubicin uptake was assessed by flow cytometry. Binding modes of compounds to P-gp were analyzed by molecular docking. Chemical features responsible for bioactivity were studied by quantitative structure activity relationship (QSAR) analyses. A 7-descriptor QSAR model was correlated with doxorubicin uptake values, IC{sub 50} values and binding energies. Results: The compounds displayed IC{sub 50} values between 0.7more »« less
https://doi.org/10.1016/J.TAAP.2016.06.002

Similar Records