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Title: Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization

Research on renewable biofuels produced by microorganisms has enjoyed considerable advances in academic and industrial settings. As the renewable ethanol market approaches maturity, the demand is rising for the commercialization of more energy-dense fuel targets. Many strategies implemented in recent years have considerably increased the diversity and number of fuel targets that can be produced by microorganisms. Moreover, strain optimization for some of these fuel targets has ultimately led to their production at industrial scale. In this review, we discuss recent metabolic engineering approaches for augmenting biofuel production derived from alcohols, isoprenoids, and fatty acids in several microorganisms. In addition, we discuss successful commercialization ventures for each class of biofuel targets.
Authors:
ORCiD logo [1] ;  [1] ; ORCiD logo [1]
  1. Joint BioEnergy Inst. (JBEI), Emeryville, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Publication Date:
Grant/Contract Number:
AC02-05CH11231
Type:
Accepted Manuscript
Journal Name:
Biotechnology Journal
Additional Journal Information:
Journal Volume: 13; Journal Issue: 1; Journal ID: ISSN 1860-6768
Publisher:
Wiley
Research Org:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
Country of Publication:
United States
Language:
English
Subject:
09 BIOMASS FUELS
OSTI Identifier:
1437002
Alternate Identifier(s):
OSTI ID: 1377945

Meadows, Corey W., Kang, Aram, and Lee, Taek S.. Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization. United States: N. p., Web. doi:10.1002/biot.201600433.
Meadows, Corey W., Kang, Aram, & Lee, Taek S.. Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization. United States. doi:10.1002/biot.201600433.
Meadows, Corey W., Kang, Aram, and Lee, Taek S.. 2017. "Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization". United States. doi:10.1002/biot.201600433. https://www.osti.gov/servlets/purl/1437002.
@article{osti_1437002,
title = {Metabolic Engineering for Advanced Biofuels Production and Recent Advances Toward Commercialization},
author = {Meadows, Corey W. and Kang, Aram and Lee, Taek S.},
abstractNote = {Research on renewable biofuels produced by microorganisms has enjoyed considerable advances in academic and industrial settings. As the renewable ethanol market approaches maturity, the demand is rising for the commercialization of more energy-dense fuel targets. Many strategies implemented in recent years have considerably increased the diversity and number of fuel targets that can be produced by microorganisms. Moreover, strain optimization for some of these fuel targets has ultimately led to their production at industrial scale. In this review, we discuss recent metabolic engineering approaches for augmenting biofuel production derived from alcohols, isoprenoids, and fatty acids in several microorganisms. In addition, we discuss successful commercialization ventures for each class of biofuel targets.},
doi = {10.1002/biot.201600433},
journal = {Biotechnology Journal},
number = 1,
volume = 13,
place = {United States},
year = {2017},
month = {7}
}

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