A narrow open tubular column for high efficiency liquid chromatographic separation

Journal Article · 30 April 2018 · Analyst

DOI: https://doi.org/10.1039/C7AN02065A · OSTI ID:1434094

Chen, Huang ^[1]; Yang, Yu ^[1]; Qiao, Zhenzhen ^[2]; Xiang, Piliang ^[1]; Ren, Jiangtao ^[1]; Meng, Yunzhu ^[1]; Zhang, Kaiqi ^[1]; Juan Lu, Joann ^[1]; Liu, Shaorong  ^[1]

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1. Department of Chemistry and Biochemistry, University of Oklahoma, Norman, USA
2. Department of Microbiology and Plant Biology, University of Oklahoma, Norman, USA

We report a great feature of open tubular liquid chromatography when it is run using an extremely narrow ( e.g. , 2 μm inner diameter) open tubular column: more than 10 million plates per meter can be achieved in less than 10 min and under an elution pressure of ca. 20 bar.

• Sponsoring Organization: USDOE
• Grant/Contract Number: SC0006351
• OSTI ID: 1434094
• Journal Information: Analyst, Journal Name: Analyst Journal Issue: 9 Vol. 143; ISSN ANALAO; ISSN 0003-2654
• Publisher: Royal Society of Chemistry (RSC)Copyright Statement
• Country of Publication: United Kingdom
• Language: English