Sequence-Mandated, Distinct Assembly of Giant Molecules
Abstract
Although controlling the primary structure of synthetic polymers is itself a great challenge, the potential of sequence control for tailoring hierarchical structures remains to be exploited, especially in the creation of new and unconventional phases. A series of model amphiphilic chain-like giant molecules was designed and synthesized by interconnecting both hydrophobic and hydrophilic molecular nanoparticles in precisely defined sequence and composition to investigate their sequence-dependent phase structures. Not only compositional variation changed the self-assembled supramolecular phases, but also specific sequences induce unconventional phase formation, including Frank-Kasper phases. The formation mechanism was attributed to the conformational change driven by the collective hydrogen bonding and the sequence-mandated topology of the molecules. Lastly, these results show that sequence control in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.
- Authors:
-
- Univ. of Akron, OH (United States). Dept. of Polymer Science, College of Polymer Science and Polymer Engineering
- Univ. of Akron, OH (United States). Dept. of Chemistry
- Univ. of Akron, OH (United States). Dept. of Polymer Science, College of Polymer Science and Polymer Engineering, and Dept. of Chemistry
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS), X-ray Science Division; Northern Illinois Univ., DeKalb, IL (United States). Dept. of Chemistry and Biochemistry
- Peking Univ., Beijing (China). Key Lab. of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Center for Soft Matter Science and Engineering
- Sichuan Univ., Chengdu (China). College of Polymer Science and Engineering, State Key Lab. of Polymer Materials Engineering
- Publication Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); National Science Foundation (NSF); National Natural Science Foundation of China (NSFC)
- OSTI Identifier:
- 1432999
- Alternate Identifier(s):
- OSTI ID: 1408927
- Grant/Contract Number:
- AC02-06CH11357
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Angewandte Chemie (International Edition)
- Additional Journal Information:
- Journal Name: Angewandte Chemie (International Edition); Journal Volume: 56; Journal Issue: 47; Journal ID: ISSN 1433-7851
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE; Frank-Kasper phase; POSS; polymer; sequence; supramolecular structure; polyhedral oligomeric silsesquioxane
Citation Formats
Zhang, Wei, Lu, Xinlin, Mao, Jialin, Hsu, Chih-Hao, Mu, Gaoyan, Huang, Mingjun, Guo, Qingyun, Liu, Hao, Wesdemiotis, Chrys, Li, Tao, Zhang, Wen-Bin, Li, Yiwen, and Cheng, Stephen Z.D. Sequence-Mandated, Distinct Assembly of Giant Molecules. United States: N. p., 2017.
Web. doi:10.1002/anie.201709354.
Zhang, Wei, Lu, Xinlin, Mao, Jialin, Hsu, Chih-Hao, Mu, Gaoyan, Huang, Mingjun, Guo, Qingyun, Liu, Hao, Wesdemiotis, Chrys, Li, Tao, Zhang, Wen-Bin, Li, Yiwen, & Cheng, Stephen Z.D. Sequence-Mandated, Distinct Assembly of Giant Molecules. United States. https://doi.org/10.1002/anie.201709354
Zhang, Wei, Lu, Xinlin, Mao, Jialin, Hsu, Chih-Hao, Mu, Gaoyan, Huang, Mingjun, Guo, Qingyun, Liu, Hao, Wesdemiotis, Chrys, Li, Tao, Zhang, Wen-Bin, Li, Yiwen, and Cheng, Stephen Z.D. Tue .
"Sequence-Mandated, Distinct Assembly of Giant Molecules". United States. https://doi.org/10.1002/anie.201709354. https://www.osti.gov/servlets/purl/1432999.
@article{osti_1432999,
title = {Sequence-Mandated, Distinct Assembly of Giant Molecules},
author = {Zhang, Wei and Lu, Xinlin and Mao, Jialin and Hsu, Chih-Hao and Mu, Gaoyan and Huang, Mingjun and Guo, Qingyun and Liu, Hao and Wesdemiotis, Chrys and Li, Tao and Zhang, Wen-Bin and Li, Yiwen and Cheng, Stephen Z.D.},
abstractNote = {Although controlling the primary structure of synthetic polymers is itself a great challenge, the potential of sequence control for tailoring hierarchical structures remains to be exploited, especially in the creation of new and unconventional phases. A series of model amphiphilic chain-like giant molecules was designed and synthesized by interconnecting both hydrophobic and hydrophilic molecular nanoparticles in precisely defined sequence and composition to investigate their sequence-dependent phase structures. Not only compositional variation changed the self-assembled supramolecular phases, but also specific sequences induce unconventional phase formation, including Frank-Kasper phases. The formation mechanism was attributed to the conformational change driven by the collective hydrogen bonding and the sequence-mandated topology of the molecules. Lastly, these results show that sequence control in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.},
doi = {10.1002/anie.201709354},
journal = {Angewandte Chemie (International Edition)},
number = 47,
volume = 56,
place = {United States},
year = {2017},
month = {10}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Giant Amphiphiles by Cofactor Reconstitution
journal, November 2002
- Boerakker, Mark J.; Hannink, Jurry M.; Bomans, Paul H. H.
- Angewandte Chemie International Edition, Vol. 41, Issue 22
Geometric Theory of Diblock Copolymer Phases
journal, July 2003
- Grason, Gregory M.; DiDonna, B. A.; Kamien, Randall D.
- Physical Review Letters, Vol. 91, Issue 5
Sequence Control in Polymer Chemistry through the Passerini Three-Component Reaction
journal, December 2013
- Solleder, Susanne C.; Meier, Michael A. R.
- Angewandte Chemie International Edition, Vol. 53, Issue 3
Rationally Controlling the Self-Assembly Behavior of Triarmed POSS–Organic Hybrid Macromolecules: From Giant Surfactants to Macroions
journal, June 2017
- Zhang, Wei; Chu, Yang; Mu, Gaoyan
- Macromolecules, Vol. 50, Issue 13
Sphericity and symmetry breaking in the formation of Frank–Kasper phases from one component materials
journal, November 2014
- Lee, Sangwoo; Leighton, Chris; Bates, Frank S.
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 50
Toward Controlled Hierarchical Heterogeneities in Giant Molecules with Precisely Arranged Nano Building Blocks
journal, January 2016
- Zhang, Wei; Huang, Mingjun; Su, Hao
- ACS Central Science, Vol. 2, Issue 1
Design and synthesis of digitally encoded polymers that can be decoded and erased
journal, May 2015
- Roy, Raj Kumar; Meszynska, Anna; Laure, Chloé
- Nature Communications, Vol. 6, Issue 1
Precision Synthesis and Distinct Assembly of Double-Chain Giant Surfactant Regioisomers
journal, May 2017
- Wang, Xiao-Man; Shao, Yu; Xu, Jun
- Macromolecules, Vol. 50, Issue 10
Giant Supramolecular Liquid Crystal Lattice
journal, February 2003
- Ungar, G.
- Science, Vol. 299, Issue 5610
Geometry induced sequence of nanoscale Frank–Kasper and quasicrystal mesophases in giant surfactants
journal, November 2016
- Yue, Kan; Huang, Mingjun; Marson, Ryan L.
- Proceedings of the National Academy of Sciences, Vol. 113, Issue 50
Sequence-Controlled Polymers
journal, August 2013
- Lutz, J. -F.; Ouchi, M.; Liu, D. R.
- Science, Vol. 341, Issue 6146
A strategy for sequence control in vinyl polymers via iterative controlled radical cyclization
journal, March 2016
- Hibi, Yusuke; Ouchi, Makoto; Sawamoto, Mitsuo
- Nature Communications, Vol. 7, Issue 1
Complex Arrangement of Orthogonal Nanoscale Columns via a Supramolecular Orientational Memory Effect
journal, November 2016
- Peterca, Mihai; Imam, Mohammad R.; Hudson, Steven D.
- ACS Nano, Vol. 10, Issue 11
Unexpected Consequences of Block Polydispersity on the Self-Assembly of ABA Triblock Copolymers
journal, February 2012
- Widin, Joan M.; Schmitt, Adam K.; Schmitt, Andrew L.
- Journal of the American Chemical Society, Vol. 134, Issue 8
Surface Structure and Hydration of Sequence-Specific Amphiphilic Polypeptoids for Antifouling/Fouling Release Applications
journal, August 2015
- Leng, Chuan; Buss, Hilda G.; Segalman, Rachel A.
- Langmuir, Vol. 31, Issue 34
Sequence control in polymer synthesis
journal, January 2009
- Badi, Nezha; Lutz, Jean-François
- Chemical Society Reviews, Vol. 38, Issue 12
Complex alloy structures regarded as sphere packings. II. Analysis and classification of representative structures
journal, July 1959
- Frank, F. C.; Kasper, J. S.
- Acta Crystallographica, Vol. 12, Issue 7
Iterative exponential growth of stereo- and sequence-controlled polymers
journal, September 2015
- Barnes, Jonathan C.; Ehrlich, Deborah J. C.; Gao, Angela X.
- Nature Chemistry, Vol. 7, Issue 10
Scalable synthesis of sequence-defined, unimolecular macromolecules by Flow-IEG
journal, August 2015
- Leibfarth, Frank A.; Johnson, Jeremiah A.; Jamison, Timothy F.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 34
From precision polymers to complex materials and systems
journal, April 2016
- Lutz, Jean-François; Lehn, Jean-Marie; Meijer, E. W.
- Nature Reviews Materials, Vol. 1, Issue 5
Thermal processing of diblock copolymer melts mimics metallurgy
journal, May 2017
- Kim, Kyungtae; Schulze, Morgan W.; Arora, Akash
- Science, Vol. 356, Issue 6337
Hierarchical Self-Organization of AB n Dendron-like Molecules into a Supramolecular Lattice Sequence
journal, August 2017
- Feng, Xueyan; Zhang, Ruimeng; Li, Yiwen
- ACS Central Science, Vol. 3, Issue 8
Synthesis of Non-Natural Sequence-Encoded Polymers Using Phosphoramidite Chemistry
journal, April 2015
- Al Ouahabi, Abdelaziz; Charles, Laurence; Lutz, Jean-François
- Journal of the American Chemical Society, Vol. 137, Issue 16
Selective assemblies of giant tetrahedra via precisely controlled positional interactions
journal, April 2015
- Huang, M.; Hsu, C. -H.; Wang, J.
- Science, Vol. 348, Issue 6233
Efficient and Sequence-Specific DNA-Templated Polymerization of Peptide Nucleic Acid Aldehydes
journal, November 2003
- Rosenbaum, Daniel M.; Liu, David R.
- Journal of the American Chemical Society, Vol. 125, Issue 46
Sequence-defined bioactive macrocycles via an acid-catalysed cascade reaction
journal, May 2016
- Porel, Mintu; Thornlow, Dana N.; Phan, Ngoc N.
- Nature Chemistry, Vol. 8, Issue 6
Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine
journal, January 2013
- Lewandowski, B.; De Bo, G.; Ward, J. W.
- Science, Vol. 339, Issue 6116
Rational controlled morphological transitions in the self-assembled multi-headed giant surfactants in solution
journal, January 2016
- Chu, Yang; Zhang, Wei; Lu, Xinlin
- Chemical Communications, Vol. 52, Issue 56
Entropy-Driven Crystallization Behavior in DNA-Mediated Nanoparticle Assembly
journal, June 2015
- Thaner, Ryan V.; Kim, Youngeun; Li, Ting I. N. G.
- Nano Letters, Vol. 15, Issue 8
Sequenzkontrolle in der Polymerchemie mithilfe der Passerini- Dreikomponentenreaktion
journal, December 2013
- Solleder, Susanne C.; Meier, Michael A. R.
- Angewandte Chemie, Vol. 126, Issue 3
Supramolecular dendritic liquid quasicrystals
journal, March 2004
- Zeng, Xiangbing; Ungar, Goran; Liu, Yongsong
- Nature, Vol. 428, Issue 6979
Manipulation of Self-Assembled Nanostructure Dimensions in Molecular Janus Particles
journal, June 2016
- Liu, Hao; Luo, Jiancheng; Shan, Wenpeng
- ACS Nano, Vol. 10, Issue 7
Nanoscale Phase Separation in Sequence-Defined Peptoid Diblock Copolymers
journal, September 2013
- Sun, Jing; Teran, Alexander A.; Liao, Xunxun
- Journal of the American Chemical Society, Vol. 135, Issue 38
Chemoselective Synthesis of Uniform Sequence-Coded Polyurethanes and Their Use as Molecular Tags
journal, July 2016
- Gunay, Ufuk Saim; Petit, Benoît Eric; Karamessini, Denise
- Chem, Vol. 1, Issue 1
Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals
journal, May 2016
- Suzuki, Yuta; Cardone, Giovanni; Restrepo, David
- Nature, Vol. 533, Issue 7603
Sequence-controlled methacrylic multiblock copolymers via sulfur-free RAFT emulsion polymerization
journal, October 2016
- Engelis, Nikolaos G.; Anastasaki, Athina; Nurumbetov, Gabit
- Nature Chemistry, Vol. 9, Issue 2
Discovery of a Frank-Kasper Phase in Sphere-Forming Block Copolymer Melts
journal, October 2010
- Lee, S.; Bluemle, M. J.; Bates, F. S.
- Science, Vol. 330, Issue 6002
Polymethacrylates with Polyhedral Oligomeric Silsesquioxane (POSS) Moieties: Influence of Spacer Length on Packing, Thermodynamics, and Dynamics
journal, May 2015
- Alexandris, Stelios; Franczyk, Adrian; Papamokos, George
- Macromolecules, Vol. 48, Issue 10
Complex alloy structures regarded as sphere packings. I. Definitions and basic principles
journal, March 1958
- Frank, F. C.; Kasper, J. S.
- Acta Crystallographica, Vol. 11, Issue 3
Surface-Directed Assembly of Sequence-Defined Synthetic Polymers into Networks of Hexagonally Patterned Nanoribbons with Controlled Functionalities
journal, May 2016
- Chen, Chun-Long; Zuckermann, Ronald N.; DeYoreo, James J.
- ACS Nano, Vol. 10, Issue 5
Pathway Selection in Peptide Amphiphile Assembly
journal, June 2014
- Korevaar, Peter A.; Newcomb, Christina J.; Meijer, E. W.
- Journal of the American Chemical Society, Vol. 136, Issue 24
Block Copolymer Based Nanostructures: Materials, Processes, and Applications to Electronics
journal, January 2010
- Kim, Ho-Cheol; Park, Sang-Min; Hinsberg, William D.
- Chemical Reviews, Vol. 110, Issue 1
σ Phase Formed in Conformationally Asymmetric AB-Type Block Copolymers
journal, August 2014
- Xie, Nan; Li, Weihua; Qiu, Feng
- ACS Macro Letters, Vol. 3, Issue 9
Synthesis and Thermodynamic Properties of Poly(cyclohexylethylene- b -dimethylsiloxane- b -cyclohexylethylene)
journal, September 2007
- Maheshwari, Sudeep; Tsapatsis, Michael; Bates, Frank S.
- Macromolecules, Vol. 40, Issue 18
Automated Synthesis of Monodisperse Oligomers, Featuring Sequence Control and Tailored Functionalization
journal, October 2016
- Martens, Steven; Van den Begin, Jos; Madder, Annemieke
- Journal of the American Chemical Society, Vol. 138, Issue 43
A General Approach to Sequence-Controlled Polymers Using Macrocyclic Ring Opening Metathesis Polymerization
journal, June 2015
- Gutekunst, Will R.; Hawker, Craig J.
- Journal of the American Chemical Society, Vol. 137, Issue 25
Works referencing / citing this record:
Investigation of the Locked-Unlocked Mechanism in Living Anionic Polymerization Realized with 1-(Tri-isopropoxymethylsilylphenyl)-1-phenylethylene
journal, November 2018
- Liu, Pibo; Ma, Hongwei; Han, Li
- Angewandte Chemie International Edition, Vol. 57, Issue 50
Breaking Parallel Orientation of Rods via a Dendritic Architecture toward Diverse Supramolecular Structures
journal, July 2019
- Zhang, Ruimeng; Feng, Xueyan; Zhang, Rui
- Angewandte Chemie International Edition, Vol. 58, Issue 34
Macromolecular Isomerism in Giant Molecules
journal, January 2020
- Shao, Yu; Yang, Shuguang; Zhang, Wen‐Bin
- Chemistry – A European Journal, Vol. 26, Issue 14
Polyhedral Oligomeric Silsesquioxane Hybrid Polymers: Well‐Defined Architectural Design and Potential Functional Applications
journal, July 2019
- Chen, Fang; Lin, Feng; Zhang, Qi
- Macromolecular Rapid Communications, Vol. 40, Issue 17
Controlling the Periodically Ordered Nanostructures in Ceramics: A Macromolecule‐Guided Strategy
journal, November 2019
- Guo, Qing‐Yun; Zhang, Bo‐xing; Feng, Xueyan
- Macromolecular Rapid Communications, Vol. 41, Issue 1
Identification of a Frank–Kasper Z phase from shape amphiphile self-assembly
journal, September 2019
- Su, Zebin; Hsu, Chih-Hao; Gong, Zihao
- Nature Chemistry, Vol. 11, Issue 10
Sequence isomeric giant surfactants with distinct self-assembly behaviors in solution
journal, January 2019
- Zhang, Wei; Shan, Wenpeng; Zhang, Shuailin
- Chemical Communications, Vol. 55, Issue 5
Losing supramolecular orientational memory via self-organization of a misfolded secondary structure
journal, January 2018
- Sahoo, Dipankar; Peterca, Mihai; Aqad, Emad
- Polymer Chemistry, Vol. 9, Issue 18
Symmetry-guided, divergent assembly of regio-isomeric molecular Janus particles
journal, January 2019
- Han, Di; Shao, Yu; Tao, Yang-Dan
- Chemical Communications, Vol. 55, Issue 45
Engineering self-assembly of giant molecules in the condensed state based on molecular nanoparticles
journal, January 2019
- Zhang, Wei; Liu, Yuchu; Huang, Jiahao
- Soft Matter, Vol. 15, Issue 36
Analysis of monodisperse, sequence-defined, and POSS-functionalized polyester copolymers by MALDI tandem mass spectrometry
journal, September 2018
- Mao, Jialin; Zhang, Wei; Cheng, Stephen ZD
- European Journal of Mass Spectrometry, Vol. 25, Issue 1
Encoding biological recognition in a bicomponent cell-membrane mimic
text, January 2019
- Rodriguez-Emmenegger, Cesar; Xiao, Qi; Kostina, Nina Yu.
- RWTH Aachen University
Self-Assembly and Applications of Amphiphilic Hybrid POSS Copolymers
journal, September 2018
- Chi, Hong; Wang, Mingyue; Xiao, Yiting
- Molecules, Vol. 23, Issue 10
Synthesis, Self-Assembly and Characterization of Tandem Triblock BPOSS-PDI-X Shape Amphiphiles
journal, June 2019
- Shao, Yu; Chen, Jia; Ren, Xiang-Kui
- Molecules, Vol. 24, Issue 11
Encoding biological recognition in a bicomponent cell-membrane mimic
journal, February 2019
- Rodriguez-Emmenegger, Cesar; Xiao, Qi; Kostina, Nina Yu.
- Proceedings of the National Academy of Sciences, Vol. 116, Issue 12
Investigation of the Locked-Unlocked Mechanism in Living Anionic Polymerization Realized with 1-(Tri-isopropoxymethylsilylphenyl)-1-phenylethylene
journal, November 2018
- Liu, Pibo; Ma, Hongwei; Han, Li
- Angewandte Chemie, Vol. 130, Issue 50
Breaking Parallel Orientation of Rods via a Dendritic Architecture toward Diverse Supramolecular Structures
journal, July 2019
- Zhang, Ruimeng; Feng, Xueyan; Zhang, Rui
- Angewandte Chemie, Vol. 131, Issue 34