Sequence-Mandated, Distinct Assembly of Giant Molecules
Abstract
Although controlling the primary structure of synthetic polymers is itself a great challenge, the potential of sequence control for tailoring hierarchical structures remains to be exploited, especially in the creation of new and unconventional phases. A series of model amphiphilic chain-like giant molecules was designed and synthesized by interconnecting both hydrophobic and hydrophilic molecular nanoparticles in precisely defined sequence and composition to investigate their sequence-dependent phase structures. Not only compositional variation changed the self-assembled supramolecular phases, but also specific sequences induce unconventional phase formation, including Frank-Kasper phases. The formation mechanism was attributed to the conformational change driven by the collective hydrogen bonding and the sequence-mandated topology of the molecules. Lastly, these results show that sequence control in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.
- Authors:
-
- Univ. of Akron, OH (United States). Dept. of Polymer Science, College of Polymer Science and Polymer Engineering
- Univ. of Akron, OH (United States). Dept. of Chemistry
- Univ. of Akron, OH (United States). Dept. of Polymer Science, College of Polymer Science and Polymer Engineering, and Dept. of Chemistry
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS), X-ray Science Division; Northern Illinois Univ., DeKalb, IL (United States). Dept. of Chemistry and Biochemistry
- Peking Univ., Beijing (China). Key Lab. of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Center for Soft Matter Science and Engineering
- Sichuan Univ., Chengdu (China). College of Polymer Science and Engineering, State Key Lab. of Polymer Materials Engineering
- Publication Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); National Science Foundation (NSF); National Natural Science Foundation of China (NNSFC)
- OSTI Identifier:
- 1432999
- Alternate Identifier(s):
- OSTI ID: 1408927
- Grant/Contract Number:
- AC02-06CH11357
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Angewandte Chemie (International Edition)
- Additional Journal Information:
- Journal Name: Angewandte Chemie (International Edition); Journal Volume: 56; Journal Issue: 47; Journal ID: ISSN 1433-7851
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 36 MATERIALS SCIENCE; Frank-Kasper phase; POSS; polymer; sequence; supramolecular structure; polyhedral oligomeric silsesquioxane
Citation Formats
Zhang, Wei, Lu, Xinlin, Mao, Jialin, Hsu, Chih-Hao, Mu, Gaoyan, Huang, Mingjun, Guo, Qingyun, Liu, Hao, Wesdemiotis, Chrys, Li, Tao, Zhang, Wen-Bin, Li, Yiwen, and Cheng, Stephen Z.D. Sequence-Mandated, Distinct Assembly of Giant Molecules. United States: N. p., 2017.
Web. doi:10.1002/anie.201709354.
Zhang, Wei, Lu, Xinlin, Mao, Jialin, Hsu, Chih-Hao, Mu, Gaoyan, Huang, Mingjun, Guo, Qingyun, Liu, Hao, Wesdemiotis, Chrys, Li, Tao, Zhang, Wen-Bin, Li, Yiwen, & Cheng, Stephen Z.D. Sequence-Mandated, Distinct Assembly of Giant Molecules. United States. doi:10.1002/anie.201709354.
Zhang, Wei, Lu, Xinlin, Mao, Jialin, Hsu, Chih-Hao, Mu, Gaoyan, Huang, Mingjun, Guo, Qingyun, Liu, Hao, Wesdemiotis, Chrys, Li, Tao, Zhang, Wen-Bin, Li, Yiwen, and Cheng, Stephen Z.D. Tue .
"Sequence-Mandated, Distinct Assembly of Giant Molecules". United States. doi:10.1002/anie.201709354. https://www.osti.gov/servlets/purl/1432999.
@article{osti_1432999,
title = {Sequence-Mandated, Distinct Assembly of Giant Molecules},
author = {Zhang, Wei and Lu, Xinlin and Mao, Jialin and Hsu, Chih-Hao and Mu, Gaoyan and Huang, Mingjun and Guo, Qingyun and Liu, Hao and Wesdemiotis, Chrys and Li, Tao and Zhang, Wen-Bin and Li, Yiwen and Cheng, Stephen Z.D.},
abstractNote = {Although controlling the primary structure of synthetic polymers is itself a great challenge, the potential of sequence control for tailoring hierarchical structures remains to be exploited, especially in the creation of new and unconventional phases. A series of model amphiphilic chain-like giant molecules was designed and synthesized by interconnecting both hydrophobic and hydrophilic molecular nanoparticles in precisely defined sequence and composition to investigate their sequence-dependent phase structures. Not only compositional variation changed the self-assembled supramolecular phases, but also specific sequences induce unconventional phase formation, including Frank-Kasper phases. The formation mechanism was attributed to the conformational change driven by the collective hydrogen bonding and the sequence-mandated topology of the molecules. Lastly, these results show that sequence control in synthetic polymers can have a dramatic impact on polymer properties and self-assembly.},
doi = {10.1002/anie.201709354},
journal = {Angewandte Chemie (International Edition)},
number = 47,
volume = 56,
place = {United States},
year = {2017},
month = {10}
}
Works referenced in this record:
Giant Amphiphiles by Cofactor Reconstitution
journal, November 2002
- Boerakker, Mark J.; Hannink, Jurry M.; Bomans, Paul H. H.
- Angewandte Chemie International Edition, Vol. 41, Issue 22
Geometric Theory of Diblock Copolymer Phases
journal, July 2003
- Grason, Gregory M.; DiDonna, B. A.; Kamien, Randall D.
- Physical Review Letters, Vol. 91, Issue 5
Sequence Control in Polymer Chemistry through the Passerini Three-Component Reaction
journal, December 2013
- Solleder, Susanne C.; Meier, Michael A. R.
- Angewandte Chemie International Edition, Vol. 53, Issue 3
Rationally Controlling the Self-Assembly Behavior of Triarmed POSS–Organic Hybrid Macromolecules: From Giant Surfactants to Macroions
journal, June 2017
- Zhang, Wei; Chu, Yang; Mu, Gaoyan
- Macromolecules, Vol. 50, Issue 13
Sphericity and symmetry breaking in the formation of Frank–Kasper phases from one component materials
journal, November 2014
- Lee, Sangwoo; Leighton, Chris; Bates, Frank S.
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 50
Toward Controlled Hierarchical Heterogeneities in Giant Molecules with Precisely Arranged Nano Building Blocks
journal, January 2016
- Zhang, Wei; Huang, Mingjun; Su, Hao
- ACS Central Science, Vol. 2, Issue 1
Design and synthesis of digitally encoded polymers that can be decoded and erased
journal, May 2015
- Roy, Raj Kumar; Meszynska, Anna; Laure, Chloé
- Nature Communications, Vol. 6, Issue 1
Precision Synthesis and Distinct Assembly of Double-Chain Giant Surfactant Regioisomers
journal, May 2017
- Wang, Xiao-Man; Shao, Yu; Xu, Jun
- Macromolecules, Vol. 50, Issue 10
Giant Supramolecular Liquid Crystal Lattice
journal, February 2003
- Ungar, G.
- Science, Vol. 299, Issue 5610
Geometry induced sequence of nanoscale Frank–Kasper and quasicrystal mesophases in giant surfactants
journal, November 2016
- Yue, Kan; Huang, Mingjun; Marson, Ryan L.
- Proceedings of the National Academy of Sciences, Vol. 113, Issue 50
Sequence-Controlled Polymers
journal, August 2013
- Lutz, J. -F.; Ouchi, M.; Liu, D. R.
- Science, Vol. 341, Issue 6146
A strategy for sequence control in vinyl polymers via iterative controlled radical cyclization
journal, March 2016
- Hibi, Yusuke; Ouchi, Makoto; Sawamoto, Mitsuo
- Nature Communications, Vol. 7, Issue 1
Complex Arrangement of Orthogonal Nanoscale Columns via a Supramolecular Orientational Memory Effect
journal, November 2016
- Peterca, Mihai; Imam, Mohammad R.; Hudson, Steven D.
- ACS Nano, Vol. 10, Issue 11
Unexpected Consequences of Block Polydispersity on the Self-Assembly of ABA Triblock Copolymers
journal, February 2012
- Widin, Joan M.; Schmitt, Adam K.; Schmitt, Andrew L.
- Journal of the American Chemical Society, Vol. 134, Issue 8
Surface Structure and Hydration of Sequence-Specific Amphiphilic Polypeptoids for Antifouling/Fouling Release Applications
journal, August 2015
- Leng, Chuan; Buss, Hilda G.; Segalman, Rachel A.
- Langmuir, Vol. 31, Issue 34
Sequence control in polymer synthesis
journal, January 2009
- Badi, Nezha; Lutz, Jean-François
- Chemical Society Reviews, Vol. 38, Issue 12
Complex alloy structures regarded as sphere packings. II. Analysis and classification of representative structures
journal, July 1959
- Frank, F. C.; Kasper, J. S.
- Acta Crystallographica, Vol. 12, Issue 7
Iterative exponential growth of stereo- and sequence-controlled polymers
journal, September 2015
- Barnes, Jonathan C.; Ehrlich, Deborah J. C.; Gao, Angela X.
- Nature Chemistry, Vol. 7, Issue 10
Scalable synthesis of sequence-defined, unimolecular macromolecules by Flow-IEG
journal, August 2015
- Leibfarth, Frank A.; Johnson, Jeremiah A.; Jamison, Timothy F.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 34
From precision polymers to complex materials and systems
journal, April 2016
- Lutz, Jean-François; Lehn, Jean-Marie; Meijer, E. W.
- Nature Reviews Materials, Vol. 1, Issue 5
Thermal processing of diblock copolymer melts mimics metallurgy
journal, May 2017
- Kim, Kyungtae; Schulze, Morgan W.; Arora, Akash
- Science, Vol. 356, Issue 6337
Hierarchical Self-Organization of AB n Dendron-like Molecules into a Supramolecular Lattice Sequence
journal, August 2017
- Feng, Xueyan; Zhang, Ruimeng; Li, Yiwen
- ACS Central Science, Vol. 3, Issue 8
Synthesis of Non-Natural Sequence-Encoded Polymers Using Phosphoramidite Chemistry
journal, April 2015
- Al Ouahabi, Abdelaziz; Charles, Laurence; Lutz, Jean-François
- Journal of the American Chemical Society, Vol. 137, Issue 16
Selective assemblies of giant tetrahedra via precisely controlled positional interactions
journal, April 2015
- Huang, M.; Hsu, C. -H.; Wang, J.
- Science, Vol. 348, Issue 6233
Efficient and Sequence-Specific DNA-Templated Polymerization of Peptide Nucleic Acid Aldehydes
journal, November 2003
- Rosenbaum, Daniel M.; Liu, David R.
- Journal of the American Chemical Society, Vol. 125, Issue 46
Sequence-defined bioactive macrocycles via an acid-catalysed cascade reaction
journal, May 2016
- Porel, Mintu; Thornlow, Dana N.; Phan, Ngoc N.
- Nature Chemistry, Vol. 8, Issue 6
Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine
journal, January 2013
- Lewandowski, B.; De Bo, G.; Ward, J. W.
- Science, Vol. 339, Issue 6116
Rational controlled morphological transitions in the self-assembled multi-headed giant surfactants in solution
journal, January 2016
- Chu, Yang; Zhang, Wei; Lu, Xinlin
- Chemical Communications, Vol. 52, Issue 56
Entropy-Driven Crystallization Behavior in DNA-Mediated Nanoparticle Assembly
journal, June 2015
- Thaner, Ryan V.; Kim, Youngeun; Li, Ting I. N. G.
- Nano Letters, Vol. 15, Issue 8
Sequenzkontrolle in der Polymerchemie mithilfe der Passerini- Dreikomponentenreaktion
journal, December 2013
- Solleder, Susanne C.; Meier, Michael A. R.
- Angewandte Chemie, Vol. 126, Issue 3
Supramolecular dendritic liquid quasicrystals
journal, March 2004
- Zeng, Xiangbing; Ungar, Goran; Liu, Yongsong
- Nature, Vol. 428, Issue 6979
Manipulation of Self-Assembled Nanostructure Dimensions in Molecular Janus Particles
journal, June 2016
- Liu, Hao; Luo, Jiancheng; Shan, Wenpeng
- ACS Nano, Vol. 10, Issue 7
Nanoscale Phase Separation in Sequence-Defined Peptoid Diblock Copolymers
journal, September 2013
- Sun, Jing; Teran, Alexander A.; Liao, Xunxun
- Journal of the American Chemical Society, Vol. 135, Issue 38
Chemoselective Synthesis of Uniform Sequence-Coded Polyurethanes and Their Use as Molecular Tags
journal, July 2016
- Gunay, Ufuk Saim; Petit, Benoît Eric; Karamessini, Denise
- Chem, Vol. 1, Issue 1
Self-assembly of coherently dynamic, auxetic, two-dimensional protein crystals
journal, May 2016
- Suzuki, Yuta; Cardone, Giovanni; Restrepo, David
- Nature, Vol. 533, Issue 7603
Sequence-controlled methacrylic multiblock copolymers via sulfur-free RAFT emulsion polymerization
journal, October 2016
- Engelis, Nikolaos G.; Anastasaki, Athina; Nurumbetov, Gabit
- Nature Chemistry, Vol. 9, Issue 2
Discovery of a Frank-Kasper Phase in Sphere-Forming Block Copolymer Melts
journal, October 2010
- Lee, S.; Bluemle, M. J.; Bates, F. S.
- Science, Vol. 330, Issue 6002
Polymethacrylates with Polyhedral Oligomeric Silsesquioxane (POSS) Moieties: Influence of Spacer Length on Packing, Thermodynamics, and Dynamics
journal, May 2015
- Alexandris, Stelios; Franczyk, Adrian; Papamokos, George
- Macromolecules, Vol. 48, Issue 10
Complex alloy structures regarded as sphere packings. I. Definitions and basic principles
journal, March 1958
- Frank, F. C.; Kasper, J. S.
- Acta Crystallographica, Vol. 11, Issue 3
Surface-Directed Assembly of Sequence-Defined Synthetic Polymers into Networks of Hexagonally Patterned Nanoribbons with Controlled Functionalities
journal, May 2016
- Chen, Chun-Long; Zuckermann, Ronald N.; DeYoreo, James J.
- ACS Nano, Vol. 10, Issue 5
Pathway Selection in Peptide Amphiphile Assembly
journal, June 2014
- Korevaar, Peter A.; Newcomb, Christina J.; Meijer, E. W.
- Journal of the American Chemical Society, Vol. 136, Issue 24
Block Copolymer Based Nanostructures: Materials, Processes, and Applications to Electronics
journal, January 2010
- Kim, Ho-Cheol; Park, Sang-Min; Hinsberg, William D.
- Chemical Reviews, Vol. 110, Issue 1
σ Phase Formed in Conformationally Asymmetric AB-Type Block Copolymers
journal, August 2014
- Xie, Nan; Li, Weihua; Qiu, Feng
- ACS Macro Letters, Vol. 3, Issue 9
Synthesis and Thermodynamic Properties of Poly(cyclohexylethylene- b -dimethylsiloxane- b -cyclohexylethylene)
journal, September 2007
- Maheshwari, Sudeep; Tsapatsis, Michael; Bates, Frank S.
- Macromolecules, Vol. 40, Issue 18
Automated Synthesis of Monodisperse Oligomers, Featuring Sequence Control and Tailored Functionalization
journal, October 2016
- Martens, Steven; Van den Begin, Jos; Madder, Annemieke
- Journal of the American Chemical Society, Vol. 138, Issue 43
A General Approach to Sequence-Controlled Polymers Using Macrocyclic Ring Opening Metathesis Polymerization
journal, June 2015
- Gutekunst, Will R.; Hawker, Craig J.
- Journal of the American Chemical Society, Vol. 137, Issue 25
Works referencing / citing this record:
Synthesis, Self-Assembly and Characterization of Tandem Triblock BPOSS-PDI-X Shape Amphiphiles
journal, June 2019
- Shao, Yu; Chen, Jia; Ren, Xiang-Kui
- Molecules, Vol. 24, Issue 11
Synthesis, Self-Assembly and Characterization of Tandem Triblock BPOSS-PDI-X Shape Amphiphiles
journal, June 2019
- Shao, Yu; Chen, Jia; Ren, Xiang-Kui
- Molecules, Vol. 24, Issue 11
Analysis of monodisperse, sequence-defined, and POSS-functionalized polyester copolymers by MALDI tandem mass spectrometry
journal, September 2018
- Mao, Jialin; Zhang, Wei; Cheng, Stephen ZD
- European Journal of Mass Spectrometry, Vol. 25, Issue 1
Investigation of the Locked-Unlocked Mechanism in Living Anionic Polymerization Realized with 1-(Tri-isopropoxymethylsilylphenyl)-1-phenylethylene
journal, November 2018
- Liu, Pibo; Ma, Hongwei; Han, Li
- Angewandte Chemie International Edition, Vol. 57, Issue 50
Breaking Parallel Orientation of Rods via a Dendritic Architecture toward Diverse Supramolecular Structures
journal, July 2019
- Zhang, Ruimeng; Feng, Xueyan; Zhang, Rui
- Angewandte Chemie International Edition, Vol. 58, Issue 34
Macromolecular Isomerism in Giant Molecules
journal, January 2020
- Shao, Yu; Yang, Shuguang; Zhang, Wen‐Bin
- Chemistry – A European Journal, Vol. 26, Issue 14
Polyhedral Oligomeric Silsesquioxane Hybrid Polymers: Well‐Defined Architectural Design and Potential Functional Applications
journal, July 2019
- Chen, Fang; Lin, Feng; Zhang, Qi
- Macromolecular Rapid Communications, Vol. 40, Issue 17
Controlling the Periodically Ordered Nanostructures in Ceramics: A Macromolecule‐Guided Strategy
journal, November 2019
- Guo, Qing‐Yun; Zhang, Bo‐xing; Feng, Xueyan
- Macromolecular Rapid Communications, Vol. 41, Issue 1
Identification of a Frank–Kasper Z phase from shape amphiphile self-assembly
journal, September 2019
- Su, Zebin; Hsu, Chih-Hao; Gong, Zihao
- Nature Chemistry, Vol. 11, Issue 10
Sequence isomeric giant surfactants with distinct self-assembly behaviors in solution
journal, January 2019
- Zhang, Wei; Shan, Wenpeng; Zhang, Shuailin
- Chemical Communications, Vol. 55, Issue 5
Losing supramolecular orientational memory via self-organization of a misfolded secondary structure
journal, January 2018
- Sahoo, Dipankar; Peterca, Mihai; Aqad, Emad
- Polymer Chemistry, Vol. 9, Issue 18
Symmetry-guided, divergent assembly of regio-isomeric molecular Janus particles
journal, January 2019
- Han, Di; Shao, Yu; Tao, Yang-Dan
- Chemical Communications, Vol. 55, Issue 45
Engineering self-assembly of giant molecules in the condensed state based on molecular nanoparticles
journal, January 2019
- Zhang, Wei; Liu, Yuchu; Huang, Jiahao
- Soft Matter, Vol. 15, Issue 36
Encoding biological recognition in a bicomponent cell-membrane mimic
text, January 2019
- Rodriguez-Emmenegger, Cesar; Xiao, Qi; Kostina, Nina Yu.
- RWTH Aachen University
Self-Assembly and Applications of Amphiphilic Hybrid POSS Copolymers
journal, September 2018
- Chi, Hong; Wang, Mingyue; Xiao, Yiting
- Molecules, Vol. 23, Issue 10