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Title: Macrophage-mediated delivery of light activated nitric oxide prodrugs with spatial, temporal and concentration control

Macrophage-mediated targeting and photochemical release provides spatial-temporal control of nitric oxide delivery to tumor spheroids.
Authors:
 [1] ;  [2] ;  [3] ;  [4] ;  [5] ;  [3] ; ORCiD logo [2] ; ORCiD logo [4]
  1. Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, 93106 USA, Department of Chemical Engineering
  2. Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, 93106 USA
  3. Department of Chemistry and Biochemistry, Doshisha University, Kyoto 610-0394, Japan
  4. Department of Chemical Engineering, Center for Bioengineering, University of California, Santa Barbara, Santa Barbara, 93106 USA
  5. Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, USA
Publication Date:
Grant/Contract Number:
AC02-05CH11231
Type:
Published Article
Journal Name:
Chemical Science
Additional Journal Information:
Journal Volume: 9; Journal Issue: 15; Related Information: CHORUS Timestamp: 2018-04-18 07:39:28; Journal ID: ISSN 2041-6520
Publisher:
Royal Society of Chemistry (RSC)
Sponsoring Org:
USDOE
Country of Publication:
United Kingdom
Language:
English
OSTI Identifier:
1430141