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Title: Hard-sphere-like dynamics in highly concentrated alpha-crystallin suspensions

Abstract

The dynamics of concentrated suspensions of the eye-lens protein alpha crystallin have been measured using x-ray photon correlation spectroscopy. Measurements were made at wave vectors corresponding to the first peak in the hard-sphere structure factor and volume fractions close to the critical volume fraction for the glass transition. Langevin dynamics simulations were also performed in parallel to the experiments. The intermediate scattering function f(q,τ) could be fit using a stretched exponential decay for both experiments and numerical simulations. The measured relaxation times show good agreement with simulations for polydisperse hard-sphere colloids.

Authors:
 [1];  [1];  [1];  [2];  [1];  [1];  [3];  [3];  [3];  [3];  [4];  [5];  [5];  [5];  [5]
  1. Northern Illinois Univ., DeKalb, IL (United States)
  2. Rochester Inst. of Technology, Rochester, NY (United States)
  3. Argonne National Lab. (ANL), Lemont, IL (United States)
  4. Univ. Paris-Sud, Orsay (France)
  5. AGH - Univ. of Science and Technology, Krakow (Poland)
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE Office of Science (SC); National Institutes of Health (NIH)
OSTI Identifier:
1427480
Alternate Identifier(s):
OSTI ID: 1419369
Grant/Contract Number:  
AC02-06CH11357
Resource Type:
Accepted Manuscript
Journal Name:
Physical Review E
Additional Journal Information:
Journal Volume: 97; Journal Issue: 2; Journal ID: ISSN 2470-0045
Publisher:
American Physical Society (APS)
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS

Citation Formats

Vodnala, Preeti, Karunaratne, Nuwan, Lurio, Laurence, Thurston, George M., Vega, Michael, Gaillard, Elizabeth, Narayanan, Suresh, Sandy, Alec, Zhang, Qingteng, Dufresne, Eric M., Foffi, Giuseppe, Grybos, Pawel, Kmon, Piotr, Maj, Piotr, and Szczygiel, Robert. Hard-sphere-like dynamics in highly concentrated alpha-crystallin suspensions. United States: N. p., 2018. Web. doi:10.1103/PhysRevE.97.020601.
Vodnala, Preeti, Karunaratne, Nuwan, Lurio, Laurence, Thurston, George M., Vega, Michael, Gaillard, Elizabeth, Narayanan, Suresh, Sandy, Alec, Zhang, Qingteng, Dufresne, Eric M., Foffi, Giuseppe, Grybos, Pawel, Kmon, Piotr, Maj, Piotr, & Szczygiel, Robert. Hard-sphere-like dynamics in highly concentrated alpha-crystallin suspensions. United States. doi:10.1103/PhysRevE.97.020601.
Vodnala, Preeti, Karunaratne, Nuwan, Lurio, Laurence, Thurston, George M., Vega, Michael, Gaillard, Elizabeth, Narayanan, Suresh, Sandy, Alec, Zhang, Qingteng, Dufresne, Eric M., Foffi, Giuseppe, Grybos, Pawel, Kmon, Piotr, Maj, Piotr, and Szczygiel, Robert. Fri . "Hard-sphere-like dynamics in highly concentrated alpha-crystallin suspensions". United States. doi:10.1103/PhysRevE.97.020601. https://www.osti.gov/servlets/purl/1427480.
@article{osti_1427480,
title = {Hard-sphere-like dynamics in highly concentrated alpha-crystallin suspensions},
author = {Vodnala, Preeti and Karunaratne, Nuwan and Lurio, Laurence and Thurston, George M. and Vega, Michael and Gaillard, Elizabeth and Narayanan, Suresh and Sandy, Alec and Zhang, Qingteng and Dufresne, Eric M. and Foffi, Giuseppe and Grybos, Pawel and Kmon, Piotr and Maj, Piotr and Szczygiel, Robert},
abstractNote = {The dynamics of concentrated suspensions of the eye-lens protein alpha crystallin have been measured using x-ray photon correlation spectroscopy. Measurements were made at wave vectors corresponding to the first peak in the hard-sphere structure factor and volume fractions close to the critical volume fraction for the glass transition. Langevin dynamics simulations were also performed in parallel to the experiments. The intermediate scattering function f(q,τ) could be fit using a stretched exponential decay for both experiments and numerical simulations. The measured relaxation times show good agreement with simulations for polydisperse hard-sphere colloids.},
doi = {10.1103/PhysRevE.97.020601},
journal = {Physical Review E},
number = 2,
volume = 97,
place = {United States},
year = {2018},
month = {2}
}

Journal Article:
Free Publicly Available Full Text
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Cited by: 2 works
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Figures / Tables:

FIG. 1 FIG. 1: Fits to SAXS from alpha crystallin suspensions vs. concentration. Data are normalized by their volume fractions. In order of largest to smallest intensity at low q, 44.5 mg/ml, 89 mg/ml, 250 mg/ml, 290 mg/ml, 300 mg/ml, 310 mg/ml, 320 mg/ml, 324 mg/ml, 325 mg/ml, 340 mg/ml, 347 mg/ml,more » 375 mg/ml, 379 mg/ml, 393 mg/ml, and 401 mg/ml.« less

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    Figures/Tables have been extracted from DOE-funded journal article accepted manuscripts.