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Title: DistributedFBA.jl: High-level, high-performance flux balance analysis in Julia

Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations. DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes. DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.
Authors:
 [1] ;  [1] ;  [1]
  1. University of Luxembourg, Esch-sur-Alzette (Luxembourg). Luxembourg Centre for Systems Biomedicine
Publication Date:
Grant/Contract Number:
SC0010429
Type:
Accepted Manuscript
Journal Name:
Bioinformatics
Additional Journal Information:
Journal Volume: 33; Journal Issue: 9; Journal ID: ISSN 1367-4803
Publisher:
Oxford University Press
Research Org:
University of Luxembourg, Esch-sur-Alzette (Luxembourg)
Sponsoring Org:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23). Biological Systems Science Division; USDOE Office of Science (SC), Advanced Scientific Computing Research (ASCR) (SC-21)
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 97 MATHEMATICS AND COMPUTING
OSTI Identifier:
1424909