skip to main content

DOE PAGESDOE PAGES

This content will become publicly available on January 1, 2019

Title: A Charge Sensitive Pre-Amplifier for Smart Point-of-Care Devices Employing Polymer Based Lab-on-a-Chip

With increasing emphasis on implantable and portable medical devices, low-power, small-chip-area sensor readout system realized in lab-on-a-chip (LOC) platform is gaining more and more importance these days. The main building blocks of the LOC system include a front-end transducer that generates an electrical signal in response to the presence of an analyte of interest, signal processing electronics to process the signal to comply with a specific transmission protocol and a low-power transmitter, all realized in a single integrated circuit platform. Low power consumption and compactness of the components are essential requirements of the LOC system. This paper presents a novel charge sensitive pre-amplifier developed in a standard 180-nm CMOS process suitable for implementing in an LOC platform. The pre-amplifier converts the charge generated by a pyroelectric transducer into a voltage signal, which provides a measurement of the temperature variation in biological fluids. The proposed design is capable of providing 0.8-mV/pC gain while consuming only 2.1 μW of power. Finally, the pre-amplifier composed of integrated components occupies an area of 0.038 mm 2.
Authors:
 [1] ;  [2] ;  [1] ;  [3] ;  [1] ;  [3] ;  [1]
  1. Univ. of Tennessee, Knoxville, TN (United States). Dept. of Electrical Engineering and Computer Science
  2. Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Tennessee, Knoxville, TN (United States). Dept. of Electrical Engineering and Computer Science
  3. Magna Graecia Univ., Catanzaro (Italy). School of Biomedical Engineering. Dept. of Health Sciences
Publication Date:
Grant/Contract Number:
AC05-00OR22725
Type:
Accepted Manuscript
Journal Name:
IEEE Transactions on Circuits and Systems. II, Express Briefs
Additional Journal Information:
Journal Name: IEEE Transactions on Circuits and Systems. II, Express Briefs; Journal ID: ISSN 1549-7747
Publisher:
IEEE
Research Org:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Tennessee, Knoxville, TN (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; charge amplifier; lab-on-a-chip (LOC); pyroelectric materials; PVDF; CMOS technology
OSTI Identifier:
1422600