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Title: A Numerical Model of Exchange Chromatography Through 3D Lattice Structures

Abstract

Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. Here, the front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array.

Authors:
ORCiD logo [1];  [1]
+ Show Author Affiliations
  1. Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Publication Date:
Research Org.:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
1421768
Alternate Identifier(s):
OSTI ID: 1422267
Report Number(s):
SAND-2018-1363J
Journal ID: ISSN 0001-1541; 660572
Grant/Contract Number:  
AC04-94AL85000; DE‐NA‐0003525
Resource Type:
Accepted Manuscript
Journal Name:
AIChE Journal
Additional Journal Information:
Journal Volume: 64; Journal Issue: 5; Journal ID: ISSN 0001-1541
Publisher:
American Institute of Chemical Engineers
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING

Citation Formats

Salloum, Maher, and Robinson, David B. A Numerical Model of Exchange Chromatography Through 3D Lattice Structures. United States: N. p., 2018. Web. doi:10.1002/aic.16108.
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Salloum, Maher, & Robinson, David B. A Numerical Model of Exchange Chromatography Through 3D Lattice Structures. United States. https://doi.org/10.1002/aic.16108
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Salloum, Maher, and Robinson, David B. Tue . "A Numerical Model of Exchange Chromatography Through 3D Lattice Structures". United States. https://doi.org/10.1002/aic.16108. https://www.osti.gov/servlets/purl/1421768.
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@article{osti_1421768,
title = {A Numerical Model of Exchange Chromatography Through 3D Lattice Structures},
author = {Salloum, Maher and Robinson, David B.},
abstractNote = {Rapid progress in the development of additive manufacturing technologies is opening new opportunities to fabricate structures that control mass transport in three dimensions across a broad range of length scales. We describe a structure that can be fabricated by newly available commercial 3D printers. It contains an array of regular three-dimensional flow paths that are in intimate contact with a solid phase, and thoroughly shuffle material among the paths. We implement a chemically reacting flow model to study its behavior as an exchange chromatography column, and compare it to an array of one-dimensional flow paths that resemble more traditional honeycomb monoliths. A reaction front moves through the columns and then elutes. Here, the front is sharper at all flow rates for the structure with three-dimensional flow paths, and this structure is more robust to channel width defects than the one-dimensional array.},
doi = {10.1002/aic.16108},
journal = {AIChE Journal},
number = 5,
volume = 64,
place = {United States},
year = {2018},
month = {1}
}
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https://doi.org/10.1002/aic.16108
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Works referenced in this record:

Computational fluid dynamics simulations yielding guidelines for the ideal internal structure of monolithic liquid chromatography columns
journal, April 2003

Dispersion behavior of 3D-printed columns with homogeneous microstructures comprising differing element shapes
journal, June 2017

3D printed porous media columns with fine control of column packing morphology
journal, March 2014

Isotope separation factor and isotopic exchange rate between hydrogen and deuterium of palladium
journal, November 1995

  • Fukada, Satoshi; Fuchinoue, Katsuhiro; Nishikawa, Masabumi
  • Journal of Nuclear Materials, Vol. 226, Issue 3
  • DOI: 10.1016/0022-3115(95)00101-8

Electroless Deposition of Palladium on Macroscopic 3D-Printed Polymers with Dense Microlattice Architectures for Development of Multifunctional Composite Materials
journal, January 2017

  • Jones, Christopher G.; Mills, Bernice E.; Nishimoto, Ryan K.
  • Journal of The Electrochemical Society, Vol. 164, Issue 13
  • DOI: 10.1149/2.1341713jes

3D printed microfluidic devices: enablers and barriers
journal, January 2016

  • Waheed, Sidra; Cabot, Joan M.; Macdonald, Niall P.
  • Lab on a Chip, Vol. 16, Issue 11
  • DOI: 10.1039/C6LC00284F

Diffusional exchange of isotopes in a metal hydride sphere
journal, January 2012

  • James, Scott C.; Hamilton, John; Wolfer, Wilhelm G.
  • Chemical Engineering Science, Vol. 68, Issue 1
  • DOI: 10.1016/j.ces.2011.09.038

3D direct writing fabrication of electrodes for electrochemical storage devices
journal, June 2017

The palladium-hydrogen system
journal, September 1937

Studies of isotopic exchange between gaseous hydrogen and palladium hydride powder
journal, December 1987

Multiple Adsorption from Solutions
journal, June 1945

  • Walter, John E.
  • The Journal of Chemical Physics, Vol. 13, Issue 6
  • DOI: 10.1063/1.1724025

Separation of Hydrogen Isotopes by Chemical Isotope Exchange in Systems Involving Metal and Intermetallic Compound Hydrides
journal, July 2001

  • Andreev, Boris M.; Magomedbekov, Eldar P.
  • Separation Science and Technology, Vol. 36, Issue 8-9
  • DOI: 10.1081/SS-100104766

Longitudinal diffusion and resistance to mass transfer as causes of nonideality in chromatography
journal, September 1956

Micro Total Analysis Systems. 1. Introduction, Theory, and Technology
journal, June 2002

  • Reyes, Darwin R.; Iossifidis, Dimitri; Auroux, Pierre-Alain
  • Analytical Chemistry, Vol. 74, Issue 12
  • DOI: 10.1021/ac0202435

Numerical Simulation of Elution Chromatography for Separation of H2-HD-D2 Mixtures Using a Palladium Particle Bed
journal, December 1999

CO 2 , CH 4 and N 2 separation with a 3DFD-printed ZSM-5 monolith
journal, January 2017

Heterogeneous Ion Exchange in a Flowing System
journal, October 1944

  • Thomas, Henry C.
  • Journal of the American Chemical Society, Vol. 66, Issue 10
  • DOI: 10.1021/ja01238a017

Fully 3D-Printed Preconcentrator for Selective Extraction of Trace Elements in Seawater
journal, June 2015

Merging Open-Tubular and Packed Bed Liquid Chromatography
journal, June 2015

Longitudinal diffusion and resistance to mass transfer as causes of nonideality in chromatography
journal, December 1995

Open-Source-Based 3D Printing of Thin Silica Gel Layers in Planar Chromatography
journal, January 2017

Polydisperse tube diameters compromise multiple open tubular chromatographyw
journal, June 1993

Separation Factors for Hydrogen Isotopes in Palladium Hydride
journal, June 2013

  • Luo, Weifang; Cowgill, Donald F.; Flanagan, Ted B.
  • The Journal of Physical Chemistry C, Vol. 117, Issue 27
  • DOI: 10.1021/jp4032332

Understanding and design of existing and future chromatographic support formats
journal, October 2007

Effects of surface thermodynamics on hydrogen isotope exchange kinetics in palladium: Particle and flow models
journal, January 2015

The Palladium-Hydrogen System
journal, August 1991

Additive Manufacturing in Fluid Process Engineering
journal, January 2016

  • Femmer, Tim; Flack, Ina; Wessling, Matthias
  • Chemie Ingenieur Technik, Vol. 88, Issue 5
  • DOI: 10.1002/cite.201500086

Theory of open-tube chromatography: an exact proof of Golay's equations
journal, June 1989

Modeling of hydrogen isotopes separation in a metal hydride bed
journal, January 1999

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    3D-Printed Stationary Phases with Ordered Morphology: State of the Art and Future Development in Liquid Chromatography
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