Use of Interrupted Helium Flow in the Analysis of Vapor Samples with Flowing Atmospheric-Pressure Afterglow-Mass Spectrometry

Storey, Andrew P.; Zeiri, Offer M.; Ray, Steven J.; Hieftje, Gary M.

doi:10.1007/s13361-016-1520-z

Title: Use of Interrupted Helium Flow in the Analysis of Vapor Samples with Flowing Atmospheric-Pressure Afterglow-Mass Spectrometry

Journal Article · 17 October 2016 · Journal of the American Society for Mass Spectrometry

DOI: https://doi.org/10.1007/s13361-016-1520-z · OSTI ID:1421370

Storey, Andrew P. ^[1]; Zeiri, Offer M. ^[2]; Ray, Steven J. ^[3]; Hieftje, Gary M. ^[4]

Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry; INDIANA UNIVERSITY
Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry; Nuclear Research Center Negev, Beer-Sheva (Israel)
Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry; Univ. at Buffalo, NY (United States); State Univ. of New York, Buffalo, NY (United States)
Indiana Univ., Bloomington, IN (United States). Dept. of Chemistry

The flowing atmospheric-pressure afterglow (FAPA) source was used for the mass-spectrometric analysis of vapor samples introduced between the source and mass spectrometer inlet. Through interrupted operation of the plasma-supporting helium flow, helium consumption is greatly reduced and dynamic gas behavior occurs that was characterized by schlieren imaging. Moreover, mass spectra acquired immediately after the onset of helium flow exhibit a signal spike before declining and ultimately reaching a steady level. This initial signal appears to be due to greater interaction of sample vapor with the afterglow of the source when helium flow resumes. In part, the initial spike in signal can be attributed to a pooling of analyte vapor in the absence of helium flow from the source. Finally, time-resolved schlieren imaging of the helium flow during on and off cycles provided insight into gas-flow patterns between the FAPA source and the MS inlet that were correlated with mass-spectral data.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Indiana Univ., Bloomington, IN (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22). Chemical Sciences, Geosciences & Biosciences Division

Grant/Contract Number:: FG02-98ER14890

OSTI ID:: 1421370

Journal Information:: Journal of the American Society for Mass Spectrometry, Journal Name: Journal of the American Society for Mass Spectrometry Journal Issue: 2 Vol. 28; ISSN 1044-0305

Publisher:: American Society for Mass SpectrometryCopyright Statement

Country of Publication:: United States

Language:: English

References (15)

Helium conservation by discontinuous introduction in the flowing atmospheric-pressure afterglow source for ambient desorption-ionization mass spectrometry Storey, Andrew P.; Zeiri, Offer M.; Ray, Steven J. Journal of Analytical Atomic Spectrometry, Vol. 30, Issue 9 https://doi.org/10.1039/C5JA00228A	journal	January 2015
Measurement and Visualization of Mass Transport for the Flowing Atmospheric Pressure Afterglow (FAPA) Ambient Mass-Spectrometry Source Pfeuffer, Kevin P.; Ray, Steven J.; Hieftje, Gary M. Journal of The American Society for Mass Spectrometry, Vol. 25, Issue 5 https://doi.org/10.1007/s13361-014-0843-x	journal	March 2014
Real-Time Analysis of Ambient Organic Aerosols Using Aerosol Flowing Atmospheric-Pressure Afterglow Mass Spectrometry (AeroFAPA-MS) Brüggemann, Martin; Karu, Einar; Stelzer, Torsten Environmental Science & Technology, Vol. 49, Issue 9 https://doi.org/10.1021/es506186c	journal	April 2015
The Effects of Added Hydrogen on a Helium Atmospheric-Pressure Plasma Jet Ambient Desorption/Ionization Source Wright, Jonathan P.; Heywood, Matthew S.; Thurston, Glen K. Journal of The American Society for Mass Spectrometry, Vol. 24, Issue 3 https://doi.org/10.1007/s13361-012-0558-9	journal	February 2013
A new, versatile, direct-current helium atmospheric-pressure glow discharge Andrade, Francisco J.; Wetzel, William C.; Chan, George C. -Y. Journal of Analytical Atomic Spectrometry, Vol. 21, Issue 11 https://doi.org/10.1039/b607544d	journal	January 2006
Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization Takats, Z. Science, Vol. 306, Issue 5695, p. 471-473 https://doi.org/10.1126/science.1104404	journal	October 2004
Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions Cody, Robert B.; Laramée, James A.; Durst, H. Dupont Analytical Chemistry, Vol. 77, Issue 8, p. 2297-2302 https://doi.org/10.1021/ac050162j	journal	April 2005
Ionization Mechanism of Positive-Ion Direct Analysis in Real Time: A Transient Microenvironment Concept Song, Liguo; Gibson, Stephen C.; Bhandari, Deepak Analytical Chemistry, Vol. 81, Issue 24 https://doi.org/10.1021/ac901122b	journal	December 2009
Ultrasensitive Ambient Mass Spectrometric Analysis with a Pin-to-Capillary Flowing Atmospheric-Pressure Afterglow Source Shelley, Jacob T.; Wiley, Joshua S.; Hieftje, Gary M. Analytical Chemistry, Vol. 83, Issue 14 https://doi.org/10.1021/ac201053q	journal	July 2011
Low-Temperature Plasma Probe for Ambient Desorption Ionization Harper, Jason D.; Charipar, Nicholas A.; Mulligan, Christopher C. Analytical Chemistry, Vol. 80, Issue 23 https://doi.org/10.1021/ac801641a	journal	December 2008
Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization Liu, Xiao-Pan; Wang, Hao-Yang; Zhang, Jun-Ting Scientific Reports, Vol. 5, Issue 1 https://doi.org/10.1038/srep16893	journal	November 2015
Understanding the Flowing Atmospheric-Pressure Afterglow (FAPA) Ambient Ionization Source through Optical Means Shelley, Jacob T.; Chan, George C. -Y.; Hieftje, Gary M. Journal of The American Society for Mass Spectrometry, Vol. 23, Issue 2 https://doi.org/10.1007/s13361-011-0292-8	journal	November 2011
Schlieren visualization of fluid dynamics effects in direct analysis in real time mass spectrometry: Schlieren DART-MS Curtis, Matthew; Keelor, Joel D.; Jones, Christina M. Rapid Communications in Mass Spectrometry, Vol. 29, Issue 5 https://doi.org/10.1002/rcm.7119	journal	January 2015
Halo-Shaped Flowing Atmospheric Pressure Afterglow: A Heavenly Design for Simplified Sample Introduction and Improved Ionization in Ambient Mass Spectrometry Pfeuffer, Kevin P.; Schaper, J. Niklas; Shelley, Jacob T. Analytical Chemistry, Vol. 85, Issue 15 https://doi.org/10.1021/ac401524x	journal	July 2013
Visualization of mass transport and heat transfer in the FAPA ambient ionization source Pfeuffer, Kevin P.; Shelley, Jacob T.; Ray, Steven J. Journal of Analytical Atomic Spectrometry, Vol. 28, Issue 3 https://doi.org/10.1039/c3ja30353e	journal	January 2013

Similar Records

Optical and mass-spectral characterization of mixed-gas flowing atmospheric-pressure afterglow sources

Journal Article · 2021 · Spectrochimica Acta. Part B, Atomic Spectroscopy · OSTI ID:1841163

Badal, Sunil P.; Farnsworth, Paul B.; Chan, George C.-Y.; +3 more

Microplasma-based flowing atmospheric-pressure afterglow (FAPA) source for ambient desorption-ionization mass spectrometry

Journal Article · 2018 · Analytica Chimica Acta · OSTI ID:1421374

Zeiri, Offer M.; Storey, Andrew P.; Ray, Steven J.; +1 more

Plasma-Based Ambient Desorption/Ionization Mass Spectrometry for the Analysis of Liquid Crystals Employed in Display Devices

Journal Article · 2019 · Journal of the American Society for Mass Spectrometry · OSTI ID:22925075

Kuhlmann, Christopher; Shelley, Jacob T.; Engelhard, Carsten

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Ambient ionization
Ion sources
Vapor analysis
Gas-flow dynamics
Helium conservation

Title: Use of Interrupted Helium Flow in the Analysis of Vapor Samples with Flowing Atmospheric-Pressure Afterglow-Mass Spectrometry

Citation Formats

References (15)

Similar Records

Related Subjects