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Title: Vibrational Studies of Saccharide-Induced Lipid Film Reorganization at Aqueous/Air Interfaces

Vibrational sum frequency generation (VSFG) and surface tension experiments were used to examine the effects of aqueous phase soluble saccharides on the structure and organization of insoluble lipid monolayers adsorbed to aqueous-air interfaces. Changes in dipalmitoylphosphocholine (DPPC) chain structure as a function of aqueous phase saccharide concentration and pH are reported. Complementary differential scanning calorimetry (DSC) measurements performed on solutions containing soluble saccharides and DPPC vesicles measured the effects of the saccharides on the lipid membrane phase behavior. Here, data show that the saccharides glucosamine and glucuronic acid induce a higher degree of organization in compressed DPPC monolayers regardless of the saccharide’s charge.
Authors:
 [1] ;  [1] ;  [2] ;  [3] ;  [2] ;  [4] ;  [1]
  1. Montana State Univ., Bozeman, MT (United States)
  2. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  3. Washington State Univ., Pullman, WA (United States)
  4. Fudan Univ., Shanghai (China)
Publication Date:
Grant/Contract Number:
AC05-76RL01830
Type:
Accepted Manuscript
Journal Name:
Chemical Physics
Additional Journal Information:
Journal Volume: 512; Journal ID: ISSN 0301-0104
Publisher:
Elsevier
Research Org:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; Phospholipid; Sum frequency generation; Cooperative adsorption; Isotherm; Calorimetry
OSTI Identifier:
1420436