Genomic features of bacterial adaptation to plants
Abstract
Plants intimately associate with diverse bacteria. Plant-associated bacteria have ostensibly evolved genes that enable them to adapt to plant environments. However, the identities of such genes are mostly unknown, and their functions are poorly characterized. We sequenced 484 genomes of bacterial isolates from roots of Brassicaceae, poplar, and maize. We then compared 3,837 bacterial genomes to identify thousands of plant-associated gene clusters. Genomes of plant-associated bacteria encode more carbohydrate metabolism functions and fewer mobile elements than related non-plant-associated genomes do. We experimentally validated candidates from two sets of plant-associated genes: one involved in plant colonization, and the other serving in microbe-microbe competition between plant-associated bacteria. We also identified 64 plant-associated protein domains that potentially mimic plant domains; some are shared with plant-associated fungi and oomycetes. This work expands the genome-based understanding of plant-microbe interactions and provides potential leads for efficient and sustainable agriculture through microbiome engineering.
- Authors:
-
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- USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States)
- Univ. of North Carolina, Chapel Hill, NC (United States). Department of Biology; Howard Hughes Medical Institute, Chevy Chase, MD (United States)
- Institute of Microbiology, ETH Zurich (Switzerland)
- Univ. of North Carolina, Chapel Hill, NC (United States). Department of Biology; Howard Hughes Medical Institute, Chevy Chase, MD (United States); Stanford Univ., CA (United States). Department of Biology
- Virginia Tech, Blacksburg, VA (United States). Department of Horticulture; Gansu Agricultural University (China). The Grassland College
- Virginia Tech, Blacksburg, VA (United States). Department of Horticulture
- International Centre for Genetic Engineering and Biotechnology, Trieste (Italy)
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Biosciences Division
- Univ. of Tennessee, Knoxville, TN (United States). Department of Microbiology
- Cornell Univ., Ithaca, NY (United States). Department of Molecular Biology and Genetics
- Univ. of North Carolina, Chapel Hill, NC (United States). Department of Biology; Howard Hughes Medical Institute, Chevy Chase, MD (United States); BD Technologies and Innovation, Research Triangle Park, NC (United States)
- Univ. of North Carolina, Chapel Hill, NC (United States). Department of Biology
- Univ. of Washington, Seattle, WA (United States). School of Environmental and Forest Sciences
- Max Planck Institute for Developmental Biology, Tubingen (Germany)
- USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States); University of California, Merced, CA (United States)
- Univ. of North Carolina, Chapel Hill, NC (United States). Department of Biology, The Carolina Center for Genome Sciences and Department of Microbiology and Immunology; Howard Hughes Medical Institute, Chevy Chase, MD (United States)
- Publication Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC)
- Sponsoring Org.:
- USDOE Office of Science (SC), Biological and Environmental Research (BER); USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23), Biological Systems Science Division (SC-23.2 )
- OSTI Identifier:
- 1415202
- Alternate Identifier(s):
- OSTI ID: 1529504; OSTI ID: 1571092
- Grant/Contract Number:
- AC05-00OR22725; AC02-05CH11231; SC0010423; SC0014395
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Nature Genetics
- Additional Journal Information:
- Journal Volume: 50; Journal Issue: 1; Journal ID: ISSN 1061-4036
- Publisher:
- Nature Publishing Group
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Levy, Asaf, Salas Gonzalez, Isai, Mittelviefhaus, Maximilian, Clingenpeel, Scott, Herrera Paredes, Sur, Miao, Jiamin, Wang, Kunru, Devescovi, Giulia, Stillman, Kyra, Monteiro, Freddy, Rangel Alvarez, Bryan, Lundberg, Derek S., Lu, Tse-Yuan, Lebeis, Sarah, Jin, Zhao, McDonald, Meredith, Klein, Andrew P., Feltcher, Meghan E., Rio, Tijana Glavina, Grant, Sarah R., Doty, Sharon L., Ley, Ruth E., Zhao, Bingyu, Venturi, Vittorio, Pelletier, Dale A., Vorholt, Julia A., Tringe, Susannah G., Woyke, Tanja, and Dangl, Jeffery L. Genomic features of bacterial adaptation to plants. United States: N. p., 2017.
Web. doi:10.1038/s41588-017-0012-9.
Levy, Asaf, Salas Gonzalez, Isai, Mittelviefhaus, Maximilian, Clingenpeel, Scott, Herrera Paredes, Sur, Miao, Jiamin, Wang, Kunru, Devescovi, Giulia, Stillman, Kyra, Monteiro, Freddy, Rangel Alvarez, Bryan, Lundberg, Derek S., Lu, Tse-Yuan, Lebeis, Sarah, Jin, Zhao, McDonald, Meredith, Klein, Andrew P., Feltcher, Meghan E., Rio, Tijana Glavina, Grant, Sarah R., Doty, Sharon L., Ley, Ruth E., Zhao, Bingyu, Venturi, Vittorio, Pelletier, Dale A., Vorholt, Julia A., Tringe, Susannah G., Woyke, Tanja, & Dangl, Jeffery L. Genomic features of bacterial adaptation to plants. United States. https://doi.org/10.1038/s41588-017-0012-9
Levy, Asaf, Salas Gonzalez, Isai, Mittelviefhaus, Maximilian, Clingenpeel, Scott, Herrera Paredes, Sur, Miao, Jiamin, Wang, Kunru, Devescovi, Giulia, Stillman, Kyra, Monteiro, Freddy, Rangel Alvarez, Bryan, Lundberg, Derek S., Lu, Tse-Yuan, Lebeis, Sarah, Jin, Zhao, McDonald, Meredith, Klein, Andrew P., Feltcher, Meghan E., Rio, Tijana Glavina, Grant, Sarah R., Doty, Sharon L., Ley, Ruth E., Zhao, Bingyu, Venturi, Vittorio, Pelletier, Dale A., Vorholt, Julia A., Tringe, Susannah G., Woyke, Tanja, and Dangl, Jeffery L. Mon .
"Genomic features of bacterial adaptation to plants". United States. https://doi.org/10.1038/s41588-017-0012-9. https://www.osti.gov/servlets/purl/1415202.
@article{osti_1415202,
title = {Genomic features of bacterial adaptation to plants},
author = {Levy, Asaf and Salas Gonzalez, Isai and Mittelviefhaus, Maximilian and Clingenpeel, Scott and Herrera Paredes, Sur and Miao, Jiamin and Wang, Kunru and Devescovi, Giulia and Stillman, Kyra and Monteiro, Freddy and Rangel Alvarez, Bryan and Lundberg, Derek S. and Lu, Tse-Yuan and Lebeis, Sarah and Jin, Zhao and McDonald, Meredith and Klein, Andrew P. and Feltcher, Meghan E. and Rio, Tijana Glavina and Grant, Sarah R. and Doty, Sharon L. and Ley, Ruth E. and Zhao, Bingyu and Venturi, Vittorio and Pelletier, Dale A. and Vorholt, Julia A. and Tringe, Susannah G. and Woyke, Tanja and Dangl, Jeffery L.},
abstractNote = {Plants intimately associate with diverse bacteria. Plant-associated bacteria have ostensibly evolved genes that enable them to adapt to plant environments. However, the identities of such genes are mostly unknown, and their functions are poorly characterized. We sequenced 484 genomes of bacterial isolates from roots of Brassicaceae, poplar, and maize. We then compared 3,837 bacterial genomes to identify thousands of plant-associated gene clusters. Genomes of plant-associated bacteria encode more carbohydrate metabolism functions and fewer mobile elements than related non-plant-associated genomes do. We experimentally validated candidates from two sets of plant-associated genes: one involved in plant colonization, and the other serving in microbe-microbe competition between plant-associated bacteria. We also identified 64 plant-associated protein domains that potentially mimic plant domains; some are shared with plant-associated fungi and oomycetes. This work expands the genome-based understanding of plant-microbe interactions and provides potential leads for efficient and sustainable agriculture through microbiome engineering.},
doi = {10.1038/s41588-017-0012-9},
journal = {Nature Genetics},
number = 1,
volume = 50,
place = {United States},
year = {Mon Dec 18 00:00:00 EST 2017},
month = {Mon Dec 18 00:00:00 EST 2017}
}
Web of Science
Figures / Tables:
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