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Title: An age-specific biokinetic model for iodine

Abstract

This study reviews age-specific biokinetic data for iodine in humans and extends to pre-adult ages the baseline parameter values of the author’s previously published model for systemic iodine in adult humans. Compared with the ICRP’s current age-specific model for iodine introduced in Publication 56 (1989), the present model provides a more detailed description of the behavior of iodine in the human body; predicts greater cumulative (integrated) activity in the thyroid for short-lived isotopes of iodine; predicts similar cumulative activity in the thyroid for isotopes with half-time greater than a few hours; and, for most iodine isotopes, predicts much greater cumulative activity in salivary glands, stomach wall, liver, and kidneys.

Authors:
ORCiD logo [1]
  1. Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1409264
Grant/Contract Number:  
AC05-00OR22725
Resource Type:
Accepted Manuscript
Journal Name:
Journal of Radiological Protection
Additional Journal Information:
Journal Volume: 37; Journal Issue: 4; Journal ID: ISSN 0952-4746
Publisher:
IOP Publishing
Country of Publication:
United States
Language:
English
Subject:
61 RADIATION PROTECTION AND DOSIMETRY; iodine; biokinetics; model; age-specific

Citation Formats

Leggett, Richard Wayne. An age-specific biokinetic model for iodine. United States: N. p., 2017. Web. https://doi.org/10.1088/1361-6498/aa8d30.
Leggett, Richard Wayne. An age-specific biokinetic model for iodine. United States. https://doi.org/10.1088/1361-6498/aa8d30
Leggett, Richard Wayne. Thu . "An age-specific biokinetic model for iodine". United States. https://doi.org/10.1088/1361-6498/aa8d30. https://www.osti.gov/servlets/purl/1409264.
@article{osti_1409264,
title = {An age-specific biokinetic model for iodine},
author = {Leggett, Richard Wayne},
abstractNote = {This study reviews age-specific biokinetic data for iodine in humans and extends to pre-adult ages the baseline parameter values of the author’s previously published model for systemic iodine in adult humans. Compared with the ICRP’s current age-specific model for iodine introduced in Publication 56 (1989), the present model provides a more detailed description of the behavior of iodine in the human body; predicts greater cumulative (integrated) activity in the thyroid for short-lived isotopes of iodine; predicts similar cumulative activity in the thyroid for isotopes with half-time greater than a few hours; and, for most iodine isotopes, predicts much greater cumulative activity in salivary glands, stomach wall, liver, and kidneys.},
doi = {10.1088/1361-6498/aa8d30},
journal = {Journal of Radiological Protection},
number = 4,
volume = 37,
place = {United States},
year = {2017},
month = {10}
}

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Cited by: 5 works
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Works referenced in this record:

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    Works referencing / citing this record:

    Repeated KI Prophylaxis in Case of Prolonged Exposure to Iodine Radioisotopes: Pharmacokinetic Studies in Adult Rats
    journal, October 2018


    Adaptive biokinetic modelling of iodine-131 in thyroid cancer treatments: implications on individualised internal dosimetry
    journal, November 2018

    • Guiu-Souto, Jacobo; Neira-Castro, Sara; Sánchez-García, Manuel
    • Journal of Radiological Protection, Vol. 38, Issue 4
    • DOI: 10.1088/1361-6498/aae44e

    Use of Iodine-131 to Tellurium-132 Ratios for Assessing the Relationships between Human Inhaled Radioactivity and Environmental Monitoring after the Accident in Fukushima
    journal, March 2018

    • Uchiyama, Koji; Miyashita, Masami; Tanishima, Yoshinobu
    • International Journal of Environmental Research and Public Health, Vol. 15, Issue 3
    • DOI: 10.3390/ijerph15030483