Selective binding of choline by a phosphate-coordination-based triple helicate featuring an aromatic box
Abstract
In nature, proteins have evolved sophisticated cavities tailored for capturing target guests selectively among competitors of similar size, shape, and charge. The fundamental principles guiding the molecular recognition, such as self-assembly and complementarity, have inspired the development of biomimetic receptors. In the current work, we report a self-assembled triple anion helicate (host 2) featuring a cavity resembling that of the choline-binding protein ChoX, as revealed by crystal and density functional theory (DFT)-optimized structures, which binds choline in a unique dual-site-binding mode. Here, this similarity in structure leads to a similarly high selectivity of host 2 for choline over its derivatives, as demonstrated by the NMR and fluorescence competition experiments. Furthermore, host 2 is able to act as a fluorescence displacement sensor for discriminating choline, acetylcholine, l-carnitine, and glycine betaine effectively.
- Authors:
-
[2];
- Northwest Univ., Xi'an (China)
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Institute of Organic and Biochemistry, Prague (Czech Republic); Charles Univ. in Prague, Albertov (Czech Republic)
- Institute of Organic Chemistry and Biochemistry, Prague (Czech Republic); Palacky Univ., Olomouc (Czech Republic)
- Ben-Gurion Univ. of the Negev, Beer-Sheva (Israel)
- Publication Date:
- Research Org.:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1408031
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Nature Communications
- Additional Journal Information:
- Journal Volume: 8; Journal Issue: 1; Journal ID: ISSN 2041-1723
- Publisher:
- Nature Publishing Group
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Jia, Chuandong, Zuo, Wei, Yang, Dong, Chen, Yanming, Cao, Liping, Custelcean, Radu, Hostas, Jiri, Hobza, Pavel, Glaser, Robert, Wang, Yao -Yu, Yang, Xiao -Juan, and Wu, Biao. Selective binding of choline by a phosphate-coordination-based triple helicate featuring an aromatic box. United States: N. p., 2017.
Web. doi:10.1038/s41467-017-00915-8.
Jia, Chuandong, Zuo, Wei, Yang, Dong, Chen, Yanming, Cao, Liping, Custelcean, Radu, Hostas, Jiri, Hobza, Pavel, Glaser, Robert, Wang, Yao -Yu, Yang, Xiao -Juan, & Wu, Biao. Selective binding of choline by a phosphate-coordination-based triple helicate featuring an aromatic box. United States. https://doi.org/10.1038/s41467-017-00915-8
Jia, Chuandong, Zuo, Wei, Yang, Dong, Chen, Yanming, Cao, Liping, Custelcean, Radu, Hostas, Jiri, Hobza, Pavel, Glaser, Robert, Wang, Yao -Yu, Yang, Xiao -Juan, and Wu, Biao. Mon .
"Selective binding of choline by a phosphate-coordination-based triple helicate featuring an aromatic box". United States. https://doi.org/10.1038/s41467-017-00915-8. https://www.osti.gov/servlets/purl/1408031.
@article{osti_1408031,
title = {Selective binding of choline by a phosphate-coordination-based triple helicate featuring an aromatic box},
author = {Jia, Chuandong and Zuo, Wei and Yang, Dong and Chen, Yanming and Cao, Liping and Custelcean, Radu and Hostas, Jiri and Hobza, Pavel and Glaser, Robert and Wang, Yao -Yu and Yang, Xiao -Juan and Wu, Biao},
abstractNote = {In nature, proteins have evolved sophisticated cavities tailored for capturing target guests selectively among competitors of similar size, shape, and charge. The fundamental principles guiding the molecular recognition, such as self-assembly and complementarity, have inspired the development of biomimetic receptors. In the current work, we report a self-assembled triple anion helicate (host 2) featuring a cavity resembling that of the choline-binding protein ChoX, as revealed by crystal and density functional theory (DFT)-optimized structures, which binds choline in a unique dual-site-binding mode. Here, this similarity in structure leads to a similarly high selectivity of host 2 for choline over its derivatives, as demonstrated by the NMR and fluorescence competition experiments. Furthermore, host 2 is able to act as a fluorescence displacement sensor for discriminating choline, acetylcholine, l-carnitine, and glycine betaine effectively.},
doi = {10.1038/s41467-017-00915-8},
journal = {Nature Communications},
number = 1,
volume = 8,
place = {United States},
year = {2017},
month = {10}
}
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Figures / Tables:
Fig. 1: Structure of a ChoX-mimicking triple anion helicate receptor. a Structures of bis-bisurea ligands L1a, L1b, and L2 that can readily form the A2L3 (A= anion, L= ligand) triple helicates when coordinated with PO43− ions. b Crystal structure of complex 1, (TMA)5[(TMA)⊂ (PO4)2(L2)3] (⊂= encapsulated by; only an Mmore »
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Works referenced in this record:
Substrate-Selective Supramolecular Tandem Assays: Monitoring Enzyme Inhibition of Arginase and Diamine Oxidase by Fluorescent Dye Displacement from Calixarene and Cucurbituril Macrocycles
journal, August 2009
- Nau, Werner M.; Ghale, Garima; Hennig, Andreas
- Journal of the American Chemical Society, Vol. 131, Issue 32
A Synthetic Receptor for Choline and Carnitine
journal, November 2002
- Ballester, Pablo; Shivanyuk, Alexander; Far, Adel Rafai
- Journal of the American Chemical Society, Vol. 124, Issue 47
Self-assembled capsules based on tetrafunctionalized calix[4]resorcinarene cavitands
journal, January 2015
- Kobayashi, Kenji; Yamanaka, Masamichi
- Chemical Society Reviews, Vol. 44, Issue 2
Molecular containers in complex chemical systems
journal, January 2015
- Zarra, Salvatore; Wood, Daniel M.; Roberts, Derrick A.
- Chemical Society Reviews, Vol. 44, Issue 2
Host–guest chemistry that directly targets lysine methylation: synthetic host molecules as alternatives to bio-reagents
journal, January 2016
- Hof, Fraser
- Chemical Communications, Vol. 52, Issue 66
The Sinorhizobium meliloti ABC Transporter Cho Is Highly Specific for Choline and Expressed in Bacteroids from Medicago sativa Nodules
journal, September 2004
- Dupont, L.; Garcia, I.; Poggi, M. -C.
- Journal of Bacteriology, Vol. 186, Issue 18
Organic cage compounds – from shape-persistency to function
journal, January 2014
- Zhang, Gang; Mastalerz, Michael
- Chem. Soc. Rev., Vol. 43, Issue 6
Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein
journal, August 1991
- Sussman, J.; Harel, M.; Frolow, F.
- Science, Vol. 253, Issue 5022
Peripheral Templation Generates an M II 6 L 4 Guest-Binding Capsule
journal, April 2016
- Rizzuto, Felix J.; Wu, Wen-Yuan; Ronson, Tanya K.
- Angewandte Chemie International Edition, Vol. 55, Issue 28
A Triple Anion Helicate Assembled from a Bis(biurea) Ligand and Phosphate Ions
journal, May 2011
- Li, Shaoguang; Jia, Chuandong; Wu, Biao
- Angewandte Chemie International Edition, Vol. 50, Issue 25
Anion recognition by oligo-(thio)urea-based receptors
journal, January 2016
- Jia, Chuandong; Zuo, Wei; Zhang, Dan
- Chemical Communications, Vol. 52, Issue 62
Metal–organic molecular cages: applications of biochemical implications
journal, January 2015
- Ahmad, Nazir; Younus, Hussein A.; Chughtai, Adeel H.
- Chemical Society Reviews, Vol. 44, Issue 1
Crystal Structures of the Choline/Acetylcholine Substrate-binding Protein ChoX from Sinorhizobium meliloti in the Liganded and Unliganded-Closed States
journal, September 2008
- Oswald, Christine; Smits, Sander H. J.; Höing, Marina
- Journal of Biological Chemistry, Vol. 283, Issue 47
Selective Cavitand-Mediated Endocytosis of Targeted Imaging Agents into Live Cells
journal, April 2013
- Ghang, Yoo-Jin; Schramm, Michael P.; Zhang, Fan
- Journal of the American Chemical Society, Vol. 135, Issue 19
A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu
journal, April 2010
- Grimme, Stefan; Antony, Jens; Ehrlich, Stephan
- The Journal of Chemical Physics, Vol. 132, Issue 15
Encapsulation of Halocarbons in a Tetrahedral Anion Cage
journal, June 2015
- Yang, Dong; Zhao, Jie; Zhao, Yanxia
- Angewandte Chemie International Edition, Vol. 54, Issue 30
Reinvestigation of Calixarene-Based Artificial-Signaling Acetylcholine Receptors Useful in Neutral Aqueous (Water/Methanol) Solution
journal, January 1996
- Koh, Kwang Nak; Araki, Koji; Ikeda, Atsushi
- Journal of the American Chemical Society, Vol. 118, Issue 4
Highly Efficient Extraction of Sulfate Ions with a Tripodal Hexaurea Receptor
journal, December 2010
- Jia, Chuandong; Wu, Biao; Li, Shaoguang
- Angewandte Chemie International Edition, Vol. 50, Issue 2
Kinetically Stable Complexes in Water: The Role of Hydration and Hydrophobicity
journal, March 2004
- Biros, Shannon M.; Ullrich, Elke C.; Hof, Fraser
- Journal of the American Chemical Society, Vol. 126, Issue 9
Stabilization of reactive species by supramolecular encapsulation
journal, January 2016
- Galan, Albano; Ballester, Pablo
- Chemical Society Reviews, Vol. 45, Issue 6
Tetrahedral Anion Cage: Self-Assembly of a (PO 4 ) 4 L 4 Complex from a Tris(bisurea) Ligand
journal, April 2013
- Wu, Biao; Cui, Fengjuan; Lei, Yibo
- Angewandte Chemie International Edition, Vol. 52, Issue 19
Acetylcholine Detection at Micromolar Concentrations with the Use of an Artificial Receptor-Based Fluorescence Switch
journal, March 2008
- Korbakov, Nina; Timmerman, Peter; Lidich, Nina
- Langmuir, Vol. 24, Issue 6
Experimental and Theoretical Study for the Assessment of the Conformational Stability of Polymethylene-Bridged Heteroaromatic Dimers: A Case of Unprecedented Folding
journal, January 2016
- Rai, Sunil K.; Singh, Praveen; Kumar, Ranjeet
- Crystal Growth & Design, Vol. 16, Issue 3
Substrate Binding and Catalytic Mechanism of Human Choline Acetyltransferase † , ‡
journal, December 2006
- Kim, Ae-Ri; Rylett, R. Jane; Shilton, Brian H.
- Biochemistry, Vol. 45, Issue 49
Applications of Supramolecular Anion Recognition
journal, May 2015
- Busschaert, Nathalie; Caltagirone, Claudia; Van Rossom, Wim
- Chemical Reviews, Vol. 115, Issue 15
Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures
journal, April 2011
- Salonen, Laura M.; Ellermann, Manuel; Diederich, François
- Angewandte Chemie International Edition, Vol. 50, Issue 21
Chemosensing Ensembles for Monitoring Biomembrane Transport in Real Time
journal, January 2014
- Ghale, Garima; Lanctôt, Adrienne G.; Kreissl, Hannah T.
- Angewandte Chemie International Edition, Vol. 53, Issue 10
The Cation−π Interaction at Protein–Protein Interaction Interfaces: Developing and Learning from Synthetic Mimics of Proteins That Bind Methylated Lysines
journal, June 2012
- Daze, Kevin D.; Hof, Fraser
- Accounts of Chemical Research, Vol. 46, Issue 4
Crystal Structure of Carnitine Acetyltransferase and Implications for the Catalytic Mechanism and Fatty Acid Transport
journal, January 2003
- Jogl, Gerwald; Tong, Liang
- Cell, Vol. 112, Issue 1
Activation of a Water-Soluble Resorcinarene Cavitand at the Water–Phosphocholine Micelle Interface
journal, November 2011
- Javor, Sacha; Rebek, Julius
- Journal of the American Chemical Society, Vol. 133, Issue 43
Label-free continuous enzyme assays with macrocycle-fluorescent dye complexes
journal, July 2007
- Hennig, Andreas; Bakirci, Hüseyin; Nau, Werner M.
- Nature Methods, Vol. 4, Issue 8
Anion coordination and anion-templated assembly: Highlights from 2002 to 2004
journal, December 2006
- Gale, Philip A.; Quesada, Roberto
- Coordination Chemistry Reviews, Vol. 250, Issue 23-24
A Nexus between Theory and Experiment: Non-Empirical Quantum Mechanical Computational Methodology Applied to Cucurbit[ n ]uril⋅Guest Binding Interactions
journal, October 2016
- Hostaš, Jiří; Sigwalt, David; Šekutor, Marina
- Chemistry - A European Journal, Vol. 22, Issue 48
Catalytic Ammonia Synthesis in Homogeneous Solution-Biomimetic at Last?
journal, November 2013
- Broda, Henning; Tuczek, Felix
- Angewandte Chemie International Edition, Vol. 53, Issue 3
Pillararenes, A New Class of Macrocycles for Supramolecular Chemistry
journal, May 2012
- Xue, Min; Yang, Yong; Chi, Xiaodong
- Accounts of Chemical Research, Vol. 45, Issue 8
Operational calixarene-based fluorescent sensing systems for choline and acetylcholine and their application to enzymatic reactions
journal, January 2011
- Guo, Dong-Sheng; Uzunova, Vanya D.; Su, Xin
- Chemical Science, Vol. 2, Issue 9
Acetylcholine binding by a synthetic receptor: implications for biological recognition
journal, December 1990
- Dougherty, D.; Stauffer, D.
- Science, Vol. 250, Issue 4987
The Cation−π Interaction
journal, August 1997
- Ma, Jennifer C.; Dougherty, Dennis A.
- Chemical Reviews, Vol. 97, Issue 5
Acid Catalysis in Basic Solution: A Supramolecular Host Promotes Orthoformate Hydrolysis
journal, April 2007
- Pluth, M. D.; Bergman, R. G.; Raymond, K. N.
- Science, Vol. 316, Issue 5821
Interactions with Aromatic Rings in Chemical and Biological Recognition
journal, March 2003
- Meyer, Emmanuel A.; Castellano, Ronald K.; Diederich, François
- Angewandte Chemie International Edition, Vol. 42, Issue 11
Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices(Nobel Lecture)
journal, January 1988
- Lehn, Jean-Marie
- Angewandte Chemie International Edition in English, Vol. 27, Issue 1
The Effect of the Spacer of Bis(biurea) Ligands on the Structure of A 2 L 3 -type (A=anion) Phosphate Complexes
journal, December 2014
- Wu, Biao; Li, Shaoguang; Lei, Yibo
- Chemistry - A European Journal, Vol. 21, Issue 6
A supramolecular microenvironment strategy for transition metal catalysis
journal, December 2015
- Kaphan, D. M.; Levin, M. D.; Bergman, R. G.
- Science, Vol. 350, Issue 6265
A Hemicyanine-Conjugated Copolymer as a Highly Sensitive Fluorescent Thermometer
journal, April 2008
- Shiraishi, Yasuhiro; Miyamoto, Ryo; Hirai, Takayuki
- Langmuir, Vol. 24, Issue 8
EQNMR: a computer program for the calculation of stability constants from nuclear magnetic resonance chemical shift data
journal, January 1993
- Hynes, Michael J.
- Journal of the Chemical Society, Dalton Transactions, Issue 2
Highly efficient catalysis of the Kemp elimination in the cavity of a cubic coordination cage
journal, February 2016
- Cullen, William; Misuraca, M. Cristina; Hunter, Christopher A.
- Nature Chemistry, Vol. 8, Issue 3
Self-Aggregating Deep Cavitand Acts as a Fluorescence Displacement Sensor for Lysine Methylation
journal, August 2016
- Liu, Yang; Perez, Lizeth; Mettry, Magi
- Journal of the American Chemical Society, Vol. 138, Issue 34
Molecular containers assembled through the hydrophobic effect
journal, January 2015
- Jordan, Jacobs H.; Gibb, Bruce C.
- Chemical Society Reviews, Vol. 44, Issue 2
Tetra-phosphonate Calix[4]pyrrole Cavitands as Multitopic Receptors for the Recognition of Ion Pairs
journal, January 2015
- Ciardi, Moira; Galán, Albano; Ballester, Pablo
- Journal of the American Chemical Society, Vol. 137, Issue 5
Calixarene-based supramolecular polymerization in solution
journal, January 2012
- Guo, Dong-Sheng; Liu, Yu
- Chemical Society Reviews, Vol. 41, Issue 18
A supramolecular approach to combining enzymatic and transition metal catalysis
journal, January 2013
- Wang, Z. Jane; Clary, Kristen N.; Bergman, Robert G.
- Nature Chemistry, Vol. 5, Issue 2
Abiological Self-Assembly via Coordination: Formation of 2D Metallacycles and 3D Metallacages with Well-Defined Shapes and Sizes and Their Chemistry
journal, July 2012
- Stang, Peter J.
- Journal of the American Chemical Society, Vol. 134, Issue 29
Antibody-Free Reading of the Histone Code Using a Simple Chemical Sensor Array
journal, July 2012
- Minaker, Samuel A.; Daze, Kevin D.; Ma, Manuel C. F.
- Journal of the American Chemical Society, Vol. 134, Issue 28
Acetylcholine Recognition by a Deep, Biomimetic Pocket
journal, July 2003
- Hof, Fraser; Trembleau, Laurent; Ullrich, Elke Christine
- Angewandte Chemie International Edition, Vol. 42, Issue 27
Crystalline molecular flasks
journal, April 2011
- Inokuma, Yasuhide; Kawano, Masaki; Fujita, Makoto
- Nature Chemistry, Vol. 3, Issue 5
Amide-Based Ligands for Anion Coordination
journal, December 2006
- Kang, Sung Ok; Begum, Rowshan Ara; Bowman-James, Kristin
- Angewandte Chemie International Edition, Vol. 45, Issue 47
Program DYNAFIT for the Analysis of Enzyme Kinetic Data: Application to HIV Proteinase
journal, June 1996
- Kuzmič, Petr
- Analytical Biochemistry, Vol. 237, Issue 2
Supermolecules by Design
journal, November 1999
- Caulder, Dana L.; Raymond, Kenneth N.
- Accounts of Chemical Research, Vol. 32, Issue 11
Molecular paneling via coordination
journal, January 2001
- Fujita, Makoto; Umemoto, Kazuhiko; Yoshizawa, Michito
- Chemical Communications, Issue 6
Binding Mechanisms in Supramolecular Complexes
journal, May 2009
- Schneider, Hans-Jörg
- Angewandte Chemie International Edition, Vol. 48, Issue 22
A Triple Anion Helicate Assembled from a Bis(biurea) Ligand and Phosphate Ions
journal, May 2011
- Li, Shaoguang; Jia, Chuandong; Wu, Biao
- Angewandte Chemie, Vol. 123, Issue 25
Encapsulation of Halocarbons in a Tetrahedral Anion Cage
journal, June 2015
- Yang, Dong; Zhao, Jie; Zhao, Yanxia
- Angewandte Chemie, Vol. 127, Issue 30
Tetrahedral Anion Cage: Self-Assembly of a (PO 4 ) 4 L 4 Complex from a Tris(bisurea) Ligand
journal, April 2013
- Wu, Biao; Cui, Fengjuan; Lei, Yibo
- Angewandte Chemie, Vol. 125, Issue 19
Peripheral Templation Generates an M II 6 L 4 Guest-Binding Capsule
journal, April 2016
- Rizzuto, Felix J.; Wu, Wen-Yuan; Ronson, Tanya K.
- Angewandte Chemie, Vol. 128, Issue 28
Interactions with Aromatic Rings in Chemical and Biological Recognition
journal, September 2003
- Meyer, Emmanuel A.; Castellano, Ronald K.; Diederich, François
- Angewandte Chemie International Edition, Vol. 42, Issue 35
Supramolecular Chemistry
journal, December 1999
- Robinson, Brian H.; Kaler, Eric W.
- Current Opinion in Colloid & Interface Science, Vol. 4, Issue 6
Acetylcholine Detection at Micromolar Concentrations with the Use of an Artificial Receptor-Based Fluorescence Switch
dataset, January 2021
- Korbakov, Nina; Timmerman, Peter; Lidich, Nina
- SupraBank
Reinvestigation of Calixarene-Based Artificial-Signaling Acetylcholine Receptors Useful in Neutral Aqueous (Water/Methanol) Solution
dataset, January 2021
- Koh, Kwang Nak; Araki, Koji; Ikeda, Atsushi
- SupraBank
Highly Efficient Extraction of Sulfate Ions with a Tripodal Hexaurea Receptor
journal, December 2010
- Jia, Chuandong; Wu, Biao; Li, Shaoguang
- Angewandte Chemie, Vol. 123, Issue 2
A Triple Anion Helicate Assembled from a Bis(biurea) Ligand and Phosphate Ions
journal, May 2011
- Li, Shaoguang; Jia, Chuandong; Wu, Biao
- Angewandte Chemie International Edition
Interactions with Aromatic Rings in Chemical and Biological Recognition.
journal, June 2003
- Meyer, Emmanuel A.; Castellano, Ronald K.; Diederich, Francois
- ChemInform, Vol. 34, Issue 22
Amide-Based Ligands for Anion Coordination
journal, March 2007
- Kang, Sung Ok; Begum, Rowshan Ara; Bowman-James, Kristin
- ChemInform, Vol. 38, Issue 12
Works referencing / citing this record:
Multivalent Crown Ether Receptors Enable Allosteric Regulation of Anion Exchange in an Fe 4 L 6 Tetrahedron
journal, September 2018
- von Krbek, Larissa K. S.; Roberts, Derrick A.; Pilgrim, Ben S.
- Angewandte Chemie, Vol. 130, Issue 43
A Long‐Lived Halogen‐Bonding Anion Triple Helicate Accommodates Rapid Guest Exchange
journal, October 2018
- Massena, Casey J.; Decato, Daniel A.; Berryman, Orion B.
- Angewandte Chemie, Vol. 130, Issue 49
Peripheral Templation-Modulated Interconversion between an A 4 L 6 Tetrahedral Anion Cage and A 2 L 3 Triple Helicate with Guest Capture/Release
journal, January 2018
- Bai, Xuemin; Jia, Chuandong; Zhao, Yanxia
- Angewandte Chemie International Edition, Vol. 57, Issue 7
Multivalent Crown Ether Receptors Enable Allosteric Regulation of Anion Exchange in an Fe 4 L 6 Tetrahedron
journal, September 2018
- von Krbek, Larissa K. S.; Roberts, Derrick A.; Pilgrim, Ben S.
- Angewandte Chemie International Edition, Vol. 57, Issue 43
A Long-Lived Halogen-Bonding Anion Triple Helicate Accommodates Rapid Guest Exchange
journal, November 2018
- Massena, Casey J.; Decato, Daniel A.; Berryman, Orion B.
- Angewandte Chemie International Edition, Vol. 57, Issue 49
Majority-Rules Effect and Allostery in Molecular Recognition of Calix[4]arene-Based Triple-Stranded Metallohelicates
journal, June 2018
- Yamasaki, Yutaro; Shio, Hidemi; Amimoto, Tomoko
- Chemistry - A European Journal, Vol. 24, Issue 34
Anion‐Coordination‐Assisted Assembly of Supramolecular Charge‐Transfer Complexes Based on Tris(urea) Ligands
journal, January 2020
- Zhang, Dan; Hou, Le‐Kai; Zhang, Qiang
- Chemistry – A European Journal, Vol. 26, Issue 6
Anion-coordination-directed self-assemblies
journal, January 2018
- Yang, Dong; Zhao, Jie; Yang, Xiao-Juan
- Organic Chemistry Frontiers, Vol. 5, Issue 4
Chirality sensing of choline derivatives by a triple anion helicate cage through induced circular dichroism
journal, January 2018
- Zuo, Wei; Huang, Zhe; Zhao, Yanxia
- Chemical Communications, Vol. 54, Issue 53
Selective recognition of choline phosphate by tripodal hexa-urea receptors with dual binding sites: crystal and solution evidence
journal, January 2019
- Zuo, Wei; Jia, Chuandong; Zhang, Huizheng
- Chemical Science, Vol. 10, Issue 8
Chirality transcription in the anion-coordination-driven assembly of tetrahedral cages
journal, January 2020
- Fu, Jin; Zheng, Bo; Zhang, Huizheng
- Chemical Communications, Vol. 56, Issue 16
Selective recognition of acetylcholine over choline by a fluorescent cage
journal, January 2019
- Long, Augustin; Fantozzi, Nicolas; Pinet, Sandra
- Organic & Biomolecular Chemistry, Vol. 17, Issue 21
Construction and interconversion of anion-coordination-based (‘aniono’) grids and double helicates modulated by counter-cations
journal, January 2019
- Fan, Xiaoxia; Zhang, Dan; Jiang, Shiyu
- Chemical Science, Vol. 10, Issue 25
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