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Title: Measuring molecular parity nonconservation using nuclear-magnetic-resonance spectroscopy

Abstract

Here, the weak interaction does not conserve parity and therefore induces energy shifts in chiral enantiomers that should in principle be detectable in molecular spectra. Unfortunately, the magnitude of the expected shifts are small and in spectra of a mixture of enantiomers, the energy shifts are not resolvable. We propose a nuclear-magnetic-resonance (NMR) experiment in which we titrate the chirality (enantiomeric excess) of a solvent and measure the diasteriomeric splitting in the spectra of a chiral solute in order to search for an anomalous offset due to parity nonconservation (PNC). We present a proof-of-principle experiment in which we search for PNC in the 13C resonances of small molecules, and use the 1H resonances, which are insensitive to PNC, as an internal reference. We set a constraint on molecular PNC in 13C chemical shifts at a level of 10–5 ppm, and provide a discussion of important considerations in the search for molecular PNC using NMR spectroscopy.

Authors:
 [1];  [2];  [3];  [4];  [5];  [6]
+ Show Author Affiliations
  1. Univ. of Southampton, Southampton (United Kingdom); Johannes Gutenberg-Univ. Mainz, Mainz (Germany)
  2. Helmholtz-Institut Mainz, Mainz (Germany)
  3. Johannes Gutenberg-Univ. Mainz, Mainz (Germany)
  4. Petersburg Nuclear Physics Institute, Gatchina (Russia); St. Petersburg Electrotechnical Univ. LETI, St. Petersburg (Russia)
  5. Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States)
  6. Johannes Gutenberg-Univ. Mainz, Mainz (Germany); Helmholtz-Institut Mainz, Mainz (Germany); Univ. of California, Berkeley, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
OSTI Identifier:
1421838
Alternate Identifier(s):
OSTI ID: 1405554
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Accepted Manuscript
Journal Name:
Physical Review A
Additional Journal Information:
Journal Volume: 96; Journal Issue: 4; Journal ID: ISSN 2469-9926
Publisher:
American Physical Society (APS)
Country of Publication:
United States
Language:
English
Subject:
74 ATOMIC AND MOLECULAR PHYSICS

Citation Formats

Eills, J., Blanchard, J. W., Bougas, L., Kozlov, M. G., Pines, A., and Budker, D. Measuring molecular parity nonconservation using nuclear-magnetic-resonance spectroscopy. United States: N. p., 2017. Web. doi:10.1103/PhysRevA.96.042119.
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Eills, J., Blanchard, J. W., Bougas, L., Kozlov, M. G., Pines, A., & Budker, D. Measuring molecular parity nonconservation using nuclear-magnetic-resonance spectroscopy. United States. https://doi.org/10.1103/PhysRevA.96.042119
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Eills, J., Blanchard, J. W., Bougas, L., Kozlov, M. G., Pines, A., and Budker, D. Mon . "Measuring molecular parity nonconservation using nuclear-magnetic-resonance spectroscopy". United States. https://doi.org/10.1103/PhysRevA.96.042119. https://www.osti.gov/servlets/purl/1421838.
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@article{osti_1421838,
title = {Measuring molecular parity nonconservation using nuclear-magnetic-resonance spectroscopy},
author = {Eills, J. and Blanchard, J. W. and Bougas, L. and Kozlov, M. G. and Pines, A. and Budker, D.},
abstractNote = {Here, the weak interaction does not conserve parity and therefore induces energy shifts in chiral enantiomers that should in principle be detectable in molecular spectra. Unfortunately, the magnitude of the expected shifts are small and in spectra of a mixture of enantiomers, the energy shifts are not resolvable. We propose a nuclear-magnetic-resonance (NMR) experiment in which we titrate the chirality (enantiomeric excess) of a solvent and measure the diasteriomeric splitting in the spectra of a chiral solute in order to search for an anomalous offset due to parity nonconservation (PNC). We present a proof-of-principle experiment in which we search for PNC in the 13C resonances of small molecules, and use the 1H resonances, which are insensitive to PNC, as an internal reference. We set a constraint on molecular PNC in 13C chemical shifts at a level of 10–5 ppm, and provide a discussion of important considerations in the search for molecular PNC using NMR spectroscopy.},
doi = {10.1103/PhysRevA.96.042119},
journal = {Physical Review A},
number = 4,
volume = 96,
place = {United States},
year = {Mon Oct 30 00:00:00 EDT 2017},
month = {Mon Oct 30 00:00:00 EDT 2017}
}
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https://doi.org/10.1103/PhysRevA.96.042119
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