Allele surfing promotes microbial adaptation from standing variation
Abstract
Abstract The coupling of ecology and evolution during range expansions enables mutations to establish at expanding range margins and reach high frequencies. This phenomenon, called allele surfing, is thought to have caused revolutions in the gene pool of many species, most evidently in microbial communities. It has remained unclear, however, under which conditions allele surfing promotes or hinders adaptation. Here, using microbial experiments and simulations, we show that, starting with standing adaptive variation, range expansions generate a larger increase in mean fitness than spatially uniform population expansions. The adaptation gain results from ‘soft’ selective sweeps emerging from surfing beneficial mutations. The rate of these surfing events is shown to sensitively depend on the strength of genetic drift, which varies among strains and environmental conditions. More generally, allele surfing promotes the rate of adaptation per biomass produced, which could help developing biofilms and other resource‐limited populations to cope with environmental challenges.
- Authors:
-
- Univ. of California, Berkeley, CA (United States)
- Max Planck Inst. for Dynamics and Self-Organization, Gottingen (Germany)
- Univ. of Edinburgh, Scotland (United Kingdom)
- Publication Date:
- Research Org.:
- University of California, Berkeley, CA (United States)
- Sponsoring Org.:
- National Science Foundation (NSF); National Institutes of Health (NIH); USDOE Office of Science (SC)
- OSTI Identifier:
- 1418631
- Alternate Identifier(s):
- OSTI ID: 1401683
- Grant/Contract Number:
- AC02-05CH11231; DE‐AC02‐05CH11231
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Ecology Letters
- Additional Journal Information:
- Journal Volume: 19; Journal Issue: 8; Journal ID: ISSN 1461-023X
- Publisher:
- Wiley
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; Biological invasions; dynamics of adaptation; eco-evolutionary feedback; gene surfing; genetic drift; range expansions
Citation Formats
Gralka, Matti, Stiewe, Fabian, Farrell, Fred, Mobius, Wolfram, Waclaw, Bartlomiej, and Hallatschek, Oskar. Allele surfing promotes microbial adaptation from standing variation. United States: N. p., 2016.
Web. doi:10.1111/ele.12625.
Gralka, Matti, Stiewe, Fabian, Farrell, Fred, Mobius, Wolfram, Waclaw, Bartlomiej, & Hallatschek, Oskar. Allele surfing promotes microbial adaptation from standing variation. United States. https://doi.org/10.1111/ele.12625
Gralka, Matti, Stiewe, Fabian, Farrell, Fred, Mobius, Wolfram, Waclaw, Bartlomiej, and Hallatschek, Oskar. Thu .
"Allele surfing promotes microbial adaptation from standing variation". United States. https://doi.org/10.1111/ele.12625. https://www.osti.gov/servlets/purl/1418631.
@article{osti_1418631,
title = {Allele surfing promotes microbial adaptation from standing variation},
author = {Gralka, Matti and Stiewe, Fabian and Farrell, Fred and Mobius, Wolfram and Waclaw, Bartlomiej and Hallatschek, Oskar},
abstractNote = {Abstract The coupling of ecology and evolution during range expansions enables mutations to establish at expanding range margins and reach high frequencies. This phenomenon, called allele surfing, is thought to have caused revolutions in the gene pool of many species, most evidently in microbial communities. It has remained unclear, however, under which conditions allele surfing promotes or hinders adaptation. Here, using microbial experiments and simulations, we show that, starting with standing adaptive variation, range expansions generate a larger increase in mean fitness than spatially uniform population expansions. The adaptation gain results from ‘soft’ selective sweeps emerging from surfing beneficial mutations. The rate of these surfing events is shown to sensitively depend on the strength of genetic drift, which varies among strains and environmental conditions. More generally, allele surfing promotes the rate of adaptation per biomass produced, which could help developing biofilms and other resource‐limited populations to cope with environmental challenges.},
doi = {10.1111/ele.12625},
journal = {Ecology Letters},
number = 8,
volume = 19,
place = {United States},
year = {Thu Jun 16 00:00:00 EDT 2016},
month = {Thu Jun 16 00:00:00 EDT 2016}
}
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