Arabidopsis Forkhead-Associated Domain Protein 3 negatively regulates peroxisome division
Abstract
Summary Peroxisomes are ubiquitous and dynamic eukaryotic organelles capable of altering their abundance in response to environmental and developmental cues, yet the regulatory mechanism of plant peroxisome division/proliferation is unclear. To identify transcriptional regulators of the peroxisome division factor gene PEX11b , we performed a nuclear pull‐down experiment and identified Arabidopsis Forkhead‐Associated Domain Protein 3 (FHA3) as a novel protein that binds to the promoter of PEX11b . Our data supported the conclusion that, in contrast to the previously identified HY5 HOMOLOG (HYH) protein that promotes the transcription of PEX11b , FHA3 is a negative regulator of PEX11b expression and peroxisome division.
- Authors:
-
- Michigan State Univ., East Lansing, MI (United States). MSU-DOE Plant Research Laboratory
- Michigan State Univ., East Lansing, MI (United States). MSU-DOE Plant Research Laboratory; Michigan State Univ., East Lansing, MI (United States). Dept. of Plant Biology
- Publication Date:
- Research Org.:
- Michigan State Univ., East Lansing, MI (United States). MSU-DOE Plant Research Laboratory
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1596263
- Alternate Identifier(s):
- OSTI ID: 1401525
- Grant/Contract Number:
- FG02-91ER20021; DE‐FG02‐91ER20021
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of Integrative Plant Biology
- Additional Journal Information:
- Journal Volume: 59; Journal Issue: 7; Journal ID: ISSN 1672-9072
- Publisher:
- Wiley - Institute of Botany, Chinese Academy of Sciences
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Desai, Mintu, Pan, Ronghui, and Hu, Jianping. Arabidopsis Forkhead-Associated Domain Protein 3 negatively regulates peroxisome division. United States: N. p., 2017.
Web. doi:10.1111/jipb.12542.
Desai, Mintu, Pan, Ronghui, & Hu, Jianping. Arabidopsis Forkhead-Associated Domain Protein 3 negatively regulates peroxisome division. United States. https://doi.org/10.1111/jipb.12542
Desai, Mintu, Pan, Ronghui, and Hu, Jianping. Tue .
"Arabidopsis Forkhead-Associated Domain Protein 3 negatively regulates peroxisome division". United States. https://doi.org/10.1111/jipb.12542. https://www.osti.gov/servlets/purl/1596263.
@article{osti_1596263,
title = {Arabidopsis Forkhead-Associated Domain Protein 3 negatively regulates peroxisome division},
author = {Desai, Mintu and Pan, Ronghui and Hu, Jianping},
abstractNote = {Summary Peroxisomes are ubiquitous and dynamic eukaryotic organelles capable of altering their abundance in response to environmental and developmental cues, yet the regulatory mechanism of plant peroxisome division/proliferation is unclear. To identify transcriptional regulators of the peroxisome division factor gene PEX11b , we performed a nuclear pull‐down experiment and identified Arabidopsis Forkhead‐Associated Domain Protein 3 (FHA3) as a novel protein that binds to the promoter of PEX11b . Our data supported the conclusion that, in contrast to the previously identified HY5 HOMOLOG (HYH) protein that promotes the transcription of PEX11b , FHA3 is a negative regulator of PEX11b expression and peroxisome division.},
doi = {10.1111/jipb.12542},
journal = {Journal of Integrative Plant Biology},
number = 7,
volume = 59,
place = {United States},
year = {Tue Jun 06 00:00:00 EDT 2017},
month = {Tue Jun 06 00:00:00 EDT 2017}
}
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Figures / Tables:
Figure 1: FHA3 is a nuclear protein. (A) Domain structure of the FHA3 protein. Positions of the functional domains and the T-DNA insertion in the fha3-1 mutant are indicated. (B) Nuclear localization of FHA3. Confocal images were taken in tobacco leaf epidermal cells transiently co-expressing GFP-FHA3 or FHA3-GFP and Histone2B-RFP.more »
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Works referenced in this record:
The PEROXIN11 Protein Family Controls Peroxisome Proliferation in Arabidopsis
journal, January 2007
- Orth, Travis; Reumann, Sigrun; Zhang, Xinchun
- The Plant Cell, Vol. 19, Issue 1
Molecular characteristics and differential expression of two nuclear factors containing the FHA domain in Arabidopsis
journal, November 2003
- Ahn, J.
- Plant Science, Vol. 165, Issue 5
DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions
journal, January 2015
- Chen, Yongheng; Chen, Chunxia; Zhang, Zhe
- Nucleic Acids Research, Vol. 43, Issue 2
Light Induces Peroxisome Proliferation in Arabidopsis Seedlings through the Photoreceptor Phytochrome A, the Transcription Factor HY5 HOMOLOG, and the Peroxisomal Protein PEROXIN11b
journal, January 2008
- Desai, Mintu; Hu, Jianping
- Plant Physiology, Vol. 146, Issue 3
The FHA domain
journal, December 2001
- Durocher, Daniel; Jackson, Stephen P.
- FEBS Letters, Vol. 513, Issue 1
The forkhead-associated domain 2 (FHA2) in Arabidopsis plays a role in plant fertility by regulating stamen development
journal, November 2012
- Ahn, Eu-Ree; Cho, Hui-Kyung; Pai, Hyun-Sook
- Planta, Vol. 237, Issue 4
Plant peroxisomes: recent discoveries in functional complexity, organelle homeostasis, and morphological dynamics
journal, December 2016
- Reumann, Sigrun; Bartel, Bonnie
- Current Opinion in Plant Biology, Vol. 34
The conserved fission complex on peroxisomes and mitochondria
journal, June 2011
- Pan, Ronghui; Hu, Jianping
- Plant Signaling & Behavior, Vol. 6, Issue 6
Plant Peroxisomes: Biogenesis and Function
journal, June 2012
- Hu, Jianping; Baker, Alison; Bartel, Bonnie
- The Plant Cell, Vol. 24, Issue 6
The Arabidopsis HY5 gene encodes a bZIP protein that regulates stimulus-induced development of root and hypocotyl
journal, November 1997
- Oyama, T.; Shimura, Y.; Okada, K.
- Genes & Development, Vol. 11, Issue 22
AT-hook motifs identified in a wide variety of DNA-binding proteins
journal, October 1998
- Aravind, L.
- Nucleic Acids Research, Vol. 26, Issue 19
Dynamics of peroxisome abundance: a tale of division and proliferation
journal, December 2009
- Kaur, Navneet; Hu, Jianping
- Current Opinion in Plant Biology, Vol. 12, Issue 6
Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis
journal, May 2002
- Holm, M.
- Genes & Development, Vol. 16, Issue 10
AGF1, an AT-Hook Protein, Is Necessary for the Negative Feedback of AtGA3ox1 Encoding GA 3-Oxidase
journal, February 2007
- Matsushita, Akane; Furumoto, Tsuyoshi; Ishida, Sarahmi
- Plant Physiology, Vol. 143, Issue 3
Five Arabidopsis peroxin 11 homologs individually promote peroxisome elongation, duplication or aggregation
journal, May 2006
- Lingard, M. J.
- Journal of Cell Science, Vol. 119, Issue 9
Light control of peroxisome proliferation during Arabidopsis photomorphogenesis
journal, October 2008
- Hu, Jianping; Desai, Mintu
- Plant Signaling & Behavior, Vol. 3, Issue 10
Works referencing / citing this record:
Sequence and biochemical analysis of Arabidopsis SP1 protein, a regulator of organelle biogenesis
journal, June 2017
- Pan, Ronghui; Hu, Jianping
- Communicative & Integrative Biology, Vol. 10, Issue 4
Dynamics of Peroxisome Homeostasis and Its Role in Stress Response and Signaling in Plants
journal, June 2019
- Su, Tong; Li, Wenjing; Wang, Pingping
- Frontiers in Plant Science, Vol. 10
Figures/Tables have been extracted from DOE-funded journal article accepted manuscripts.