Search Menu
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information
Search Scholarly Publications

Title: Assessing task performance in FFDM, DBT, and synthetic mammography using uniform and anthropomorphic physical phantoms

Abstract

Purpose The purpose of this study is to quantify the differences in detectability between full field digital mammography (FFDM), digital breast tomosynthesis (DBT), and synthetic mammography (SM) for challenging, low contrast signals, in the context of both a uniform and an anthropomorphic, textured phantom. Methods Images of the phantoms were acquired using a Hologic Selenia Dimensions system. Images were taken at 50%, 100%, and 200% of the dose delivered under automatic exposure control (AEC). Low‐contrast disks, created using an inkjet printer with iodine‐doped ink, were inserted into the phantom. The disks varied in diameter from 210 to 630 μ m, and in local contrast from 1.1% to 2.8% in regular increments. Human observers located the disks in a 4 alternative forced choice experiment. Proportion correct (PC) was computed as the number of correct localizations out of the total number of tries. Results Overall, scores from FFDM and DBT were consistently greater than scores from SM. At an exposure corresponding to the AEC setting, mean PC scores for the largest disks with the uniform phantom were 0.80 for FFDM, 0.83 for DBT, and 0.66 for SM, with the same rank ordering at other doses. Scores were similar but lower for themore » nonuniform background. At an exposure twice the AEC setting, however, the difference between uniform and nonuniform scores was most pronounced for DBT alone. Differences between scores for FFDM and SM were statistically significant, while those between FFDM and DBT were not. Scores were used to compute the minimum contrast level needed to reach 62.5% detection rate. The minimum contrast for SM was 36%–81% higher compared to FFDM or DBT, in either background. Conclusions This study shows that an anthropomorphic phantom and lesions inserts may be used to conduct a reader study. Detectability was significantly lower for synthetic mammography than for FFDM or DBT, for all conditions. Additionally, observer performance was consistently lower for the anthropomorphic phantom, indicating the greater challenge due to anatomical background. Because of this, it may be important to use realistic phantoms in observer studies in order to draw conclusions that are more clinically relevant.« less

Authors:
; ; ; ;
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1401483
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
Medical Physics
Additional Journal Information:
Journal Name: Medical Physics Journal Volume: 43 Journal Issue: 10; Journal ID: ISSN 0094-2405
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
United States
Language:
English

Citation Formats

Ikejimba, Lynda C., Glick, Stephen J., Choudhury, Kingshuk Roy, Samei, Ehsan, and Lo, Joseph Y. Assessing task performance in FFDM, DBT, and synthetic mammography using uniform and anthropomorphic physical phantoms. United States: N. p., 2016. Web. doi:10.1118/1.4962475.
Copy to clipboard
Ikejimba, Lynda C., Glick, Stephen J., Choudhury, Kingshuk Roy, Samei, Ehsan, & Lo, Joseph Y. Assessing task performance in FFDM, DBT, and synthetic mammography using uniform and anthropomorphic physical phantoms. United States. https://doi.org/10.1118/1.4962475
Copy to clipboard
Ikejimba, Lynda C., Glick, Stephen J., Choudhury, Kingshuk Roy, Samei, Ehsan, and Lo, Joseph Y. Fri . "Assessing task performance in FFDM, DBT, and synthetic mammography using uniform and anthropomorphic physical phantoms". United States. https://doi.org/10.1118/1.4962475.
Copy to clipboard
@article{osti_1401483,
title = {Assessing task performance in FFDM, DBT, and synthetic mammography using uniform and anthropomorphic physical phantoms},
author = {Ikejimba, Lynda C. and Glick, Stephen J. and Choudhury, Kingshuk Roy and Samei, Ehsan and Lo, Joseph Y.},
abstractNote = {Purpose The purpose of this study is to quantify the differences in detectability between full field digital mammography (FFDM), digital breast tomosynthesis (DBT), and synthetic mammography (SM) for challenging, low contrast signals, in the context of both a uniform and an anthropomorphic, textured phantom. Methods Images of the phantoms were acquired using a Hologic Selenia Dimensions system. Images were taken at 50%, 100%, and 200% of the dose delivered under automatic exposure control (AEC). Low‐contrast disks, created using an inkjet printer with iodine‐doped ink, were inserted into the phantom. The disks varied in diameter from 210 to 630 μ m, and in local contrast from 1.1% to 2.8% in regular increments. Human observers located the disks in a 4 alternative forced choice experiment. Proportion correct (PC) was computed as the number of correct localizations out of the total number of tries. Results Overall, scores from FFDM and DBT were consistently greater than scores from SM. At an exposure corresponding to the AEC setting, mean PC scores for the largest disks with the uniform phantom were 0.80 for FFDM, 0.83 for DBT, and 0.66 for SM, with the same rank ordering at other doses. Scores were similar but lower for the nonuniform background. At an exposure twice the AEC setting, however, the difference between uniform and nonuniform scores was most pronounced for DBT alone. Differences between scores for FFDM and SM were statistically significant, while those between FFDM and DBT were not. Scores were used to compute the minimum contrast level needed to reach 62.5% detection rate. The minimum contrast for SM was 36%–81% higher compared to FFDM or DBT, in either background. Conclusions This study shows that an anthropomorphic phantom and lesions inserts may be used to conduct a reader study. Detectability was significantly lower for synthetic mammography than for FFDM or DBT, for all conditions. Additionally, observer performance was consistently lower for the anthropomorphic phantom, indicating the greater challenge due to anatomical background. Because of this, it may be important to use realistic phantoms in observer studies in order to draw conclusions that are more clinically relevant.},
doi = {10.1118/1.4962475},
journal = {Medical Physics},
number = 10,
volume = 43,
place = {United States},
year = {Fri Sep 23 00:00:00 EDT 2016},
month = {Fri Sep 23 00:00:00 EDT 2016}
}
Copy to clipboard
Journal Article:
Free Publicly Available Full Text
Accepted Manuscript (Publisher)
Publisher's Version of Record
https://doi.org/10.1118/1.4962475
Copyright Statement
Other availability
Search WorldCat Search WorldCat to find libraries that may hold this journal
Citation Metrics:
Cited by: 27 works
Citation information provided by
Web of Science
Save / Share:
Export Metadata
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.

Works referenced in this record:

Dose Reduction in Digital Breast Tomosynthesis (DBT) Screening using Synthetically Reconstructed Projection Images
journal, February 2012

Comparison of Digital Mammography Alone and Digital Mammography Plus Tomosynthesis in a Population-based Screening Program
journal, April 2013

Integration of 3D digital mammography with tomosynthesis for population breast-cancer screening (STORM): a prospective comparison study
journal, June 2013

Comparison of software and human observers in reading images of the CDMAM test object to assess digital mammography systems
conference, March 2006

  • Young, Kenneth C.; Cook, James J. H.; Oduko, Jennifer M.
  • Medical Imaging, SPIE Proceedings
  • DOI: 10.1117/12.653296

Digital tomosynthesis in breast imaging.
journal, November 1997

Simulation of spiculated breast lesions
conference, March 2016

  • Elangovan, Premkumar; Alrehily, Faisal; Pinto, R. Ferrari
  • SPIE Medical Imaging, SPIE Proceedings
  • DOI: 10.1117/12.2216227

How do radiographic techniques affect mass lesion detection performance in digital mammography?
conference, May 2004

  • Huda, Walter; Ogden, Kent M.; Scalzetti, Ernest M.
  • Medical Imaging 2004, SPIE Proceedings
  • DOI: 10.1117/12.535672

Clinical Digital Breast Tomosynthesis System: Dosimetric Characterization
journal, April 2012

Digital Breast Tomosynthesis: Initial Experience in 98 Women with Abnormal Digital Screening Mammography
journal, September 2007

  • Poplack, Steven P.; Tosteson, Tor D.; Kogel, Christine A.
  • American Journal of Roentgenology, Vol. 189, Issue 3
  • DOI: 10.2214/AJR.07.2231

Breast Tomosynthesis
journal, October 2011

Fusion of digital breast tomosynthesis images via wavelet synthesis for improved lesion conspicuity
conference, March 2014

  • Hariharan, Harishwaran; Pomponiu, Victor; Zheng, Bin
  • SPIE Medical Imaging, SPIE Proceedings
  • DOI: 10.1117/12.2043799

Development of a physical 3D anthropomorphic breast phantom: Development of a 3D anthropomorphic breast phantom
journal, January 2011

  • Carton, Ann-Katherine; Bakic, Predrag; Ullberg, Christer
  • Medical Physics, Vol. 38, Issue 2
  • DOI: 10.1118/1.3533896

Human observer detection experiments with mammograms and power-law noise
journal, April 2001

  • Burgess, Arthur E.; Jacobson, Francine L.; Judy, Philip F.
  • Medical Physics, Vol. 28, Issue 4
  • DOI: 10.1118/1.1355308

Digital Breast Tomosynthesis: Image Quality and Dose Saving of the Synthesized Image
book, January 2014

Generating Synthetic Mammograms From Reconstructed Tomosynthesis Volumes
journal, December 2013

  • van Schie, Guido; Mann, Ritse; Imhof-Tas, Mechli
  • IEEE Transactions on Medical Imaging, Vol. 32, Issue 12
  • DOI: 10.1109/TMI.2013.2281738

Second generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and inkjet printing of iodinated lesion inserts
conference, March 2016

  • Sikaria, Dhiraj; Musinsky, Stephanie; Sturgeon, Gregory M.
  • SPIE Medical Imaging, SPIE Proceedings
  • DOI: 10.1117/12.2217667

A novel method for producing x-ray test objects and phantoms
journal, March 2004

A comparison of the accuracy of film-screen mammography, full-field digital mammography, and digital breast tomosynthesis
journal, October 2012

    Sort by:
    [ × clear filter / sort ]

    Similar Records in DOE PAGES and OSTI.GOV collections: