skip to main content
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: The phycocyanobilin chromophore of streptophyte algal phytochromes is synthesized by HY2

Authors:
 [1];  [1];  [2];  [3]; ORCiD logo [1]
  1. Department of Molecular and Cellular Biology, University of California, Davis CA 95616 USA
  2. Department of Biology, Duke University, Durham NC 27708 USA
  3. CSIRO National Research Collections Australia, Australian National Herbarium, Canberra ACT 2601 Australia
Publication Date:
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
OSTI Identifier:
1401047
Grant/Contract Number:  
FG02-09ER16117; SC0002395
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
New Phytologist
Additional Journal Information:
Journal Name: New Phytologist Journal Volume: 214 Journal Issue: 3; Journal ID: ISSN 0028-646X
Publisher:
Wiley-Blackwell
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Rockwell, Nathan C., Martin, Shelley S., Li, Fay-Wei, Mathews, Sarah, and Lagarias, John Clark. The phycocyanobilin chromophore of streptophyte algal phytochromes is synthesized by HY2. United Kingdom: N. p., 2017. Web. doi:10.1111/nph.14422.
Rockwell, Nathan C., Martin, Shelley S., Li, Fay-Wei, Mathews, Sarah, & Lagarias, John Clark. The phycocyanobilin chromophore of streptophyte algal phytochromes is synthesized by HY2. United Kingdom. doi:10.1111/nph.14422.
Rockwell, Nathan C., Martin, Shelley S., Li, Fay-Wei, Mathews, Sarah, and Lagarias, John Clark. Fri . "The phycocyanobilin chromophore of streptophyte algal phytochromes is synthesized by HY2". United Kingdom. doi:10.1111/nph.14422.
@article{osti_1401047,
title = {The phycocyanobilin chromophore of streptophyte algal phytochromes is synthesized by HY2},
author = {Rockwell, Nathan C. and Martin, Shelley S. and Li, Fay-Wei and Mathews, Sarah and Lagarias, John Clark},
abstractNote = {},
doi = {10.1111/nph.14422},
journal = {New Phytologist},
number = 3,
volume = 214,
place = {United Kingdom},
year = {2017},
month = {1}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1111/nph.14422

Citation Metrics:
Cited by: 4 works
Citation information provided by
Web of Science

Save / Share:

Works referenced in this record:

Red/Green Cyanobacteriochromes: Sensors of Color and Power
journal, November 2012

  • Rockwell, Nathan C.; Martin, Shelley S.; Lagarias, J. Clark
  • Biochemistry, Vol. 51, Issue 48
  • DOI: 10.1021/bi3013565

(3Z)- and (3E)-phytochromobilin are intermediates in the biosynthesis of the phytochrome chromophore
journal, May 1995

  • Terry, Mj; McDowell, Mt; Lagarias, Jc
  • Journal of Biological Chemistry, Vol. 270, Issue 19
  • DOI: 10.1074/jbc.270.19.11111

Phytochrome diversity in green plants and the origin of canonical plant phytochromes
journal, July 2015

  • Li, Fay-Wei; Melkonian, Michael; Rothfels, Carl J.
  • Nature Communications, Vol. 6, Issue 1
  • DOI: 10.1038/ncomms8852

Harnessing phytochrome's glowing potential
journal, November 2004

  • Fischer, A. J.; Lagarias, J. C.
  • Proceedings of the National Academy of Sciences, Vol. 101, Issue 50
  • DOI: 10.1073/pnas.0407645101

Phylotranscriptomic analysis of the origin and early diversification of land plants
journal, October 2014

  • Wickett, Norman J.; Mirarab, Siavash; Nguyen, Nam
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 45
  • DOI: 10.1073/pnas.1323926111

Multiple Roles of a Conserved GAF Domain Tyrosine Residue in Cyanobacterial and Plant Phytochromes
journal, November 2005

  • Fischer, Amanda J.; Rockwell, Nathan C.; Jang, Abigail Y.
  • Biochemistry, Vol. 44, Issue 46
  • DOI: 10.1021/bi051633z

Genetic engineering of phytochrome biosynthesis in bacteria
journal, September 2001

  • Gambetta, G. A.; Lagarias, J. C.
  • Proceedings of the National Academy of Sciences, Vol. 98, Issue 19
  • DOI: 10.1073/pnas.191375198

Marine algae and land plants share conserved phytochrome signaling systems
journal, September 2014

  • Duanmu, D.; Bachy, C.; Sudek, S.
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 44
  • DOI: 10.1073/pnas.1416751111

New biosynthetic pathway for pink pigments from uncultured oceanic viruses: Viral pink pigments
journal, April 2016

  • Ledermann, Benjamin; Béjà, Oded; Frankenberg-Dinkel, Nicole
  • Environmental Microbiology, Vol. 18, Issue 12
  • DOI: 10.1111/1462-2920.13290

Leaf Optical Properties of Rainforest sun and Extreme Shade Plants
journal, August 1986


Conserved Phenylalanine Residues Are Required for Blue-Shifting of Cyanobacteriochrome Photoproducts
journal, May 2014

  • Rockwell, Nathan C.; Martin, Shelley S.; Gulevich, Alexander G.
  • Biochemistry, Vol. 53, Issue 19
  • DOI: 10.1021/bi500037a

The Arabidopsis thaliana HY1 locus, required for phytochrome-chromophore biosynthesis, encodes a protein related to heme oxygenases
journal, May 1999

  • Davis, S. J.; Kurepa, J.; Vierstra, R. D.
  • Proceedings of the National Academy of Sciences, Vol. 96, Issue 11
  • DOI: 10.1073/pnas.96.11.6541

Phytochrome Structure and Signaling Mechanisms
journal, June 2006


Data access for the 1,000 Plants (1KP) project
journal, October 2014


Mechanistic Insight into the Photosensory Versatility of DXCF Cyanobacteriochromes
journal, April 2012

  • Rockwell, Nathan C.; Martin, Shelley S.; Lagarias, J. Clark
  • Biochemistry, Vol. 51, Issue 17
  • DOI: 10.1021/bi300171s

Crystal Structures of the Substrate-Bound Forms of Red Chlorophyll Catabolite Reductase: Implications for Site-Specific and Stereospecific Reaction
journal, October 2010

  • Sugishima, Masakazu; Okamoto, Yukihiro; Noguchi, Masato
  • Journal of Molecular Biology, Vol. 402, Issue 5
  • DOI: 10.1016/j.jmb.2010.08.021

The Arabidopsis HY2 Gene Encodes Phytochromobilin Synthase, a Ferredoxin-Dependent Biliverdin Reductase
journal, February 2001

  • Kohchi, Takayuki; Mukougawa, Keiko; Frankenberg, Nicole
  • The Plant Cell, Vol. 13, Issue 2
  • DOI: 10.1105/tpc.13.2.425

Biliverdin Amides Reveal Roles for Propionate Side Chains in Bilin Reductase Recognition and in Holophytochrome Assembly and Photoconversion
journal, July 2010

  • Shang, Lixia; Rockwell, Nathan C.; Martin, Shelley S.
  • Biochemistry, Vol. 49, Issue 29
  • DOI: 10.1021/bi100756x

Identification of DXCF cyanobacteriochrome lineages with predictable photocycles
journal, January 2015

  • Rockwell, Nathan C.; Martin, Shelley S.; Lagarias, J. Clark
  • Photochemical & Photobiological Sciences, Vol. 14, Issue 5
  • DOI: 10.1039/C4PP00486H

Heterogeneous Photodynamics of the P fr State in the Cyanobacterial Phytochrome Cph1
journal, July 2014

  • Kim, Peter W.; Rockwell, Nathan C.; Martin, Shelley S.
  • Biochemistry, Vol. 53, Issue 28
  • DOI: 10.1021/bi5005359

Eukaryotic algal phytochromes span the visible spectrum
journal, February 2014

  • Rockwell, Nathan C.; Duanmu, Deqiang; Martin, Shelley S.
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 10
  • DOI: 10.1073/pnas.1401871111

Phycocyanobilin Is the Natural Precursor of the Phytochrome Chromophore in the Green Alga Mesotaenium caldariorum
journal, October 1997

  • Wu, Shu-Hsing; McDowell, Michael T.; Lagarias, J. Clark
  • Journal of Biological Chemistry, Vol. 272, Issue 41
  • DOI: 10.1074/jbc.272.41.25700

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
journal, September 1997

  • Altschul, Stephen F.; Madden, Thomas L.; Schäffer, Alejandro A.
  • Nucleic Acids Research, Vol. 25, Issue 17, p. 3389-3402
  • DOI: 10.1093/nar/25.17.3389

Insights into Phycoerythrobilin Biosynthesis Point toward Metabolic Channeling
journal, July 2006

  • Dammeyer, Thorben; Frankenberg-Dinkel, Nicole
  • Journal of Biological Chemistry, Vol. 281, Issue 37
  • DOI: 10.1074/jbc.M605154200

Crystal structure of the photosensing module from a red/far-red light-absorbing plant phytochrome
journal, June 2014

  • Burgie, E. S.; Bussell, A. N.; Walker, J. M.
  • Proceedings of the National Academy of Sciences, Vol. 111, Issue 28
  • DOI: 10.1073/pnas.1403096111

The Cyanobacteriochrome, TePixJ, Isomerizes Its Own Chromophore by Converting Phycocyanobilin to Phycoviolobilin
journal, February 2011

  • Ishizuka, Takami; Kamiya, Ayumi; Suzuki, Hiroyuki
  • Biochemistry, Vol. 50, Issue 6
  • DOI: 10.1021/bi101626t

Metabolic engineering to produce phytochromes with phytochromobilin, phycocyanobilin, or phycoerythrobilin chromophore in Escherichia coli
journal, January 2006


Probing protein-chromophore interactions in Cph1 phytochrome by mutagenesis
journal, April 2006


The Elm1 (Zm Hy2 ) Gene of Maize Encodes a Phytochromobilin Synthase
journal, September 2004

  • Sawers, Ruairidh J. H.; Linley, Philip J.; Gutierrez-Marcos, Jose F.
  • Plant Physiology, Vol. 136, Issue 1
  • DOI: 10.1104/pp.104.046417

The D-ring, Not the A-ring, Rotates in Synechococcus OS-B′ Phytochrome
journal, December 2013

  • Song, Chen; Psakis, Georgios; Kopycki, Jakub
  • Journal of Biological Chemistry, Vol. 289, Issue 5
  • DOI: 10.1074/jbc.M113.520031

Visualization of bilin-linked peptides and proteins in polyacrylamide gels
journal, July 1986


Why is water blue?
journal, August 1993

  • Braun, Charles L.; Smirnov, Sergei N.
  • Journal of Chemical Education, Vol. 70, Issue 8
  • DOI: 10.1021/ed070p612

Structural and mechanistic insight into the ferredoxin-mediated two-electron reduction of bilins
journal, September 2011

  • Busch, Andrea W. U.; Reijerse, Edward J.; Lubitz, Wolfgang
  • Biochemical Journal, Vol. 439, Issue 2
  • DOI: 10.1042/BJ20110814

On the Collective Nature of Phytochrome Photoactivation
journal, December 2011

  • Song, Chen; Psakis, Georgios; Lang, Christina
  • Biochemistry, Vol. 50, Issue 51
  • DOI: 10.1021/bi201504a

Phylogeny and Molecular Evolution of the Green Algae
journal, January 2012

  • Leliaert, Frederik; Smith, David R.; Moreau, Hervé
  • Critical Reviews in Plant Sciences, Vol. 31, Issue 1
  • DOI: 10.1080/07352689.2011.615705

Flexible mapping of homology onto structure with Homolmapper
journal, April 2007


Dynamic Inhomogeneity in the Photodynamics of Cyanobacterial Phytochrome Cph1
journal, April 2014

  • Kim, Peter W.; Rockwell, Nathan C.; Martin, Shelley S.
  • Biochemistry, Vol. 53, Issue 17
  • DOI: 10.1021/bi500108s

Retrograde bilin signaling enables Chlamydomonas greening and phototrophic survival
journal, January 2013

  • Duanmu, Deqiang; Casero, David; Dent, Rachel M.
  • Proceedings of the National Academy of Sciences, Vol. 110, Issue 9
  • DOI: 10.1073/pnas.1222375110

Chromopeptides from phytochrome. The structure and linkage of the PR form of the phytochrome chromophore
journal, July 1980

  • Lagarias, J. Clark; Rapoport, Henry
  • Journal of the American Chemical Society, Vol. 102, Issue 14
  • DOI: 10.1021/ja00534a042

Red-shifted red/green-type cyanobacteriochrome AM1_1870g3 from the chlorophyll d-bearing cyanobacterium Acaryochloris marina
journal, May 2015

  • Narikawa, Rei; Fushimi, Keiji
  • Biochemical and Biophysical Research Communications, Vol. 461, Issue 2
  • DOI: 10.1016/j.bbrc.2015.04.045

Untangling the early diversification of eukaryotes: a phylogenomic study of the evolutionary origins of Centrohelida, Haptophyta and Cryptista
journal, January 2016

  • Burki, Fabien; Kaplan, Maia; Tikhonenkov, Denis V.
  • Proceedings of the Royal Society B: Biological Sciences, Vol. 283, Issue 1823
  • DOI: 10.1098/rspb.2015.2802

A prokaryotic phytochrome
journal, April 1997

  • Hughes, Jon; Lamparter, Tilman; Mittmann, Franz
  • Nature, Vol. 386, Issue 6626
  • DOI: 10.1038/386663a0

Ultrafast E to Z photoisomerization dynamics of the Cph1 phytochrome
journal, October 2012


The System of Contractile Vacuoles in the Green Alga Mesostigma viride (Streptophyta)
journal, August 2009


Function and distribution of bilin biosynthesis enzymes in photosynthetic organisms
journal, January 2008

  • Dammeyer, Thorben; Frankenberg-Dinkel, Nicole
  • Photochemical & Photobiological Sciences, Vol. 7, Issue 10
  • DOI: 10.1039/b807209b

Phycoviolobilin Formation and Spectral Tuning in the DXCF Cyanobacteriochrome Subfamily
journal, February 2012

  • Rockwell, Nathan C.; Martin, Shelley S.; Gulevich, Alexander G.
  • Biochemistry, Vol. 51, Issue 7
  • DOI: 10.1021/bi201783j

Cyanophora paradoxa Genome Elucidates Origin of Photosynthesis in Algae and Plants
journal, February 2012


Type I reversible photochemistry of phycoerythrocyanin involves Z/E-isomerization of α-84 phycoviolobilin chromophore
journal, March 1995

  • Zhao, Kai-Hong; Haessner, Rainer; Cmiel, Edmund
  • Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1228, Issue 2-3
  • DOI: 10.1016/0005-2728(94)00181-4

Mechanism of Cph1 Phytochrome Assembly from Stopped-Flow Kinetics and Circular Dichroism
journal, November 2003

  • Borucki, Berthold; Otto, Harald; Rottwinkel, Gregor
  • Biochemistry, Vol. 42, Issue 46
  • DOI: 10.1021/bi035511n

Phytochrome signaling mechanisms and the control of plant development
journal, November 2011


Insight into the Radical Mechanism of Phycocyanobilin−Ferredoxin Oxidoreductase (PcyA) Revealed by X-ray Crystallography and Biochemical Measurements
journal, February 2007

  • Tu, Shih-Long; Rockwell, Nathan C.; Lagarias, J. Clark
  • Biochemistry, Vol. 46, Issue 6
  • DOI: 10.1021/bi062038f

A biliverdin-binding cyanobacteriochrome from the chlorophyll d–bearing cyanobacterium Acaryochloris marina
journal, January 2015

  • Narikawa, Rei; Nakajima, Takahiro; Aono, Yuki
  • Scientific Reports, Vol. 5, Issue 1
  • DOI: 10.1038/srep07950

Vivid watercolor paintbox for eukaryotic algae
journal, April 2014


Two ground state isoforms and a chromophore D-ring photoflip triggering extensive intramolecular changes in a canonical phytochrome
journal, February 2011

  • Song, C.; Psakis, G.; Lang, C.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 10
  • DOI: 10.1073/pnas.1013377108

A Cyanobacterial Phytochrome Two-Component Light Sensory System
journal, September 1997


Green/red cyanobacteriochromes regulate complementary chromatic acclimation via a protochromic photocycle
journal, March 2013

  • Hirose, Y.; Rockwell, N. C.; Nishiyama, K.
  • Proceedings of the National Academy of Sciences, Vol. 110, Issue 13
  • DOI: 10.1073/pnas.1302909110

Heteronuclear Solution-State NMR Studies of the Chromophore in Cyanobacterial Phytochrome Cph1
journal, June 2005

  • Strauss, Holger M.; Hughes, Jon; Schmieder, Peter
  • Biochemistry, Vol. 44, Issue 23
  • DOI: 10.1021/bi050457r

The Zoospore of Chlorokybus Atmophyticus, a Charophyte with Sarcinoid Growth Habit
journal, May 1980


Distinct phytochrome actions in nonvascular plants revealed by targeted inactivation of phytobilin biosynthesis
journal, May 2012

  • Chen, Y. -R.; Su, Y. -s.; Tu, S. -L.
  • Proceedings of the National Academy of Sciences, Vol. 109, Issue 21
  • DOI: 10.1073/pnas.1201744109

Optical modeling of the upper ocean in relation to its biogenous matter content (case I waters)
journal, January 1988


Distinct classes of red/far-red photochemistry within the phytochrome superfamily
journal, April 2009

  • Rockwell, N. C.; Shang, L.; Martin, S. S.
  • Proceedings of the National Academy of Sciences, Vol. 106, Issue 15
  • DOI: 10.1073/pnas.0902370106

Recombinant Phytochrome of the Moss Ceratodon purpureus: Heterologous Expression and Kinetic Analysis of P r → P fr Conversion
journal, December 1998


The structure of a complete phytochrome sensory module in the Pr ground state
journal, September 2008

  • Essen, L. -O.; Mailliet, J.; Hughes, J.
  • Proceedings of the National Academy of Sciences, Vol. 105, Issue 38
  • DOI: 10.1073/pnas.0806477105

Crystal structure of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin IX , a key enzyme in the biosynthesis of phycocyanobilin
journal, December 2005

  • Hagiwara, Y.; Sugishima, M.; Takahashi, Y.
  • Proceedings of the National Academy of Sciences, Vol. 103, Issue 1
  • DOI: 10.1073/pnas.0507266103

Efficient Phage-Mediated Pigment Biosynthesis in Oceanic Cyanobacteria
journal, March 2008


Photoreceptor Signaling Networks in Plant Responses to Shade
journal, April 2013


The GapA/B Gene Duplication Marks the Origin of Streptophyta (Charophytes and Land Plants)
journal, March 2006

  • Petersen, Jörn; Teich, René; Becker, Burkhard
  • Molecular Biology and Evolution, Vol. 23, Issue 6
  • DOI: 10.1093/molbev/msj123

Unraveling the Primary Isomerization Dynamics in Cyanobacterial Phytochrome Cph1 with Multipulse Manipulations
journal, July 2013

  • Kim, Peter W.; Rockwell, Nathan C.; Freer, Lucy H.
  • The Journal of Physical Chemistry Letters, Vol. 4, Issue 16
  • DOI: 10.1021/jz401443q

Diverse two-cysteine photocycles in phytochromes and cyanobacteriochromes
journal, June 2011

  • Rockwell, N. C.; Martin, S. S.; Feoktistova, K.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 29
  • DOI: 10.1073/pnas.1107844108

Phytochrome functions in Arabidopsis development
journal, October 2009

  • Franklin, K. A.; Quail, P. H.
  • Journal of Experimental Botany, Vol. 61, Issue 1
  • DOI: 10.1093/jxb/erp304

Observations on the Sexual Cycle of the Saccoderm Desmid Spirotaenia condensata
journal, January 1966

  • Hoshaw, Robert W.; Hilton, Richard L.
  • Journal of the Arizona Academy of Science, Vol. 4, Issue 2
  • DOI: 10.2307/40022376

Heterologous Expression and Characterization of Recombinant Phytochrome from the Green Alga Mougeotia scalaris¶
journal, January 2002


Accounting for Solvent Accessibility and Secondary Structure in Protein Phylogenetics Is Clearly Beneficial
journal, March 2010


Klebsormidium flaccidum genome reveals primary factors for plant terrestrial adaptation
journal, May 2014

  • Hori, Koichi; Maruyama, Fumito; Fujisawa, Takatomo
  • Nature Communications, Vol. 5, Issue 1
  • DOI: 10.1038/ncomms4978

Functional Genomic Analysis of the HY2 Family of Ferredoxin-Dependent Bilin Reductases from Oxygenic Photosynthetic Organisms
journal, April 2001

  • Frankenberg, Nicole; Mukougawa, Keiko; Kohchi, Takayuki
  • The Plant Cell, Vol. 13, Issue 4
  • DOI: 10.1105/tpc.13.4.965

Reconstitution of Blue−Green Reversible Photoconversion of a Cyanobacterial Photoreceptor, PixJ1, in Phycocyanobilin-Producing Escherichia coli
journal, March 2006

  • Yoshihara, Shizue; Shimada, Takashi; Matsuoka, Daisuke
  • Biochemistry, Vol. 45, Issue 11
  • DOI: 10.1021/bi051983l

Broad Phylogenomic Sampling and the Sister Lineage of Land Plants
journal, January 2012


Biosynthesis of phycobilins
journal, March 1993


Primary endosymbiosis and the evolution of light and oxygen sensing in photosynthetic eukaryotes
journal, October 2014

  • Rockwell, Nathan C.; Lagarias, J. C.; Bhattacharya, Debashish
  • Frontiers in Ecology and Evolution, Vol. 2
  • DOI: 10.3389/fevo.2014.00066