Chromate Binding and Removal by the Molybdate‐Binding Protein ModA

Karpus, Jason; Bosscher, Michael; Ajiboye, Ifedayo; Zhang, Liang; He, Chuan

doi:10.1002/cbic.201700051

Title: Chromate Binding and Removal by the Molybdate‐Binding Protein ModA

Journal Article · 06 March 2017 · ChemBioChem: a European journal of chemical biology

DOI: https://doi.org/10.1002/cbic.201700051 · OSTI ID:1400604

Karpus, Jason ^[1]; Bosscher, Michael ^[1]; Ajiboye, Ifedayo ^[1]; Zhang, Liang ^[1]; He, Chuan ^[1]

Department of Chemistry University of Chicago 929 East 57th Street Chicago IL 60637 USA

Abstract Effective and cheap methods and techniques for the safe removal of hexavalent chromate from the environment are in increasingly high demand. High concentrations of hexavalent chromate have been shown to have numerous harmful effects on human biology. We show that the E. coli molybdate‐binding protein ModA is a genetically encoded tool capable of removing chromate from aqueous solutions. Although previously reported to not bind chromate, we show that ModA binds chromate tightly and is capable of removing chromate to levels well below current US federal standards.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: FG02-07ER15865

OSTI ID:: 1400604

Journal Information:: ChemBioChem: a European journal of chemical biology, Journal Name: ChemBioChem: a European journal of chemical biology Journal Issue: 7 Vol. 18; ISSN 1439-4227

Publisher:: Wiley Blackwell (John Wiley & Sons)Copyright Statement

Country of Publication:: France

Language:: English

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