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Title: Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states

Authors:
 [1];  [1]
  1. Molecular and Structural Biochemistry Department, North Carolina State University, Raleigh NC USA, Neutron Sciences Directorate, Oak Ridge National Laboratory, TN USA
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1400588
Grant/Contract Number:  
AC05-00OR22725
Resource Type:
Publisher's Accepted Manuscript
Journal Name:
FEBS Letters
Additional Journal Information:
Journal Name: FEBS Letters Journal Volume: 590 Journal Issue: 23; Journal ID: ISSN 0014-5793
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
Netherlands
Language:
English

Citation Formats

Bodenheimer, Annette M., and Meilleur, Flora. Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states. Netherlands: N. p., 2016. Web. doi:10.1002/1873-3468.12464.
Bodenheimer, Annette M., & Meilleur, Flora. Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states. Netherlands. doi:10.1002/1873-3468.12464.
Bodenheimer, Annette M., and Meilleur, Flora. Mon . "Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states". Netherlands. doi:10.1002/1873-3468.12464.
@article{osti_1400588,
title = {Crystal structures of wild-type Trichoderma reesei Cel7A catalytic domain in open and closed states},
author = {Bodenheimer, Annette M. and Meilleur, Flora},
abstractNote = {},
doi = {10.1002/1873-3468.12464},
journal = {FEBS Letters},
number = 23,
volume = 590,
place = {Netherlands},
year = {2016},
month = {11}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1002/1873-3468.12464

Citation Metrics:
Cited by: 2 works
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Works referenced in this record:

Studies of the cellulolytic system of Trichoderma reesei QM 9414. Analysis of domain function in two cellobiohydrolases by limited proteolysis
journal, January 1988


Novel enzymes for the degradation of cellulose
journal, January 2012

  • Horn, Svein; Vaaje-Kolstad, Gustav; Westereng, Bjørge
  • Biotechnology for Biofuels, Vol. 5, Issue 1, Article No. 45
  • DOI: 10.1186/1754-6834-5-45

MolMovDB: analysis and visualization of conformational change and structural flexibility
journal, January 2003


Fungal Cellulases
journal, January 2015

  • Payne, Christina M.; Knott, Brandon C.; Mayes, Heather B.
  • Chemical Reviews, Vol. 115, Issue 3
  • DOI: 10.1021/cr500351c

Small Angle Neutron Scattering Reveals pH-dependent Conformational Changes in Trichoderma reesei Cellobiohydrolase I : IMPLICATIONS FOR ENZYMATIC ACTIVITY
journal, July 2011

  • Pingali, Sai Venkatesh; O'Neill, Hugh M.; McGaughey, Joseph
  • Journal of Biological Chemistry, Vol. 286, Issue 37
  • DOI: 10.1074/jbc.M111.263004

Overview of the CCP 4 suite and current developments
journal, March 2011

  • Winn, Martyn D.; Ballard, Charles C.; Cowtan, Kevin D.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444910045749

A solution for the best rotation to relate two sets of vectors
journal, September 1976


High-resolution crystal structures reveal how a cellulose chain is bound in the 50 Å long tunnel of cellobiohydrolase I from Trichoderma reesei
journal, January 1998

  • Divne, Christina; Ståhlberg, Jerry; Teeri, Tuula T.
  • Journal of Molecular Biology, Vol. 275, Issue 2, p. 309-325
  • DOI: 10.1006/jmbi.1997.1437

Alleviating product inhibition in cellulase enzyme Cel7A: Alleviating Product Inhibition in Cel7A
journal, September 2015

  • Atreya, Meera E.; Strobel, Kathryn L.; Clark, Douglas S.
  • Biotechnology and Bioengineering, Vol. 113, Issue 2
  • DOI: 10.1002/bit.25809

A New Model For Enzymatic Hydrolysis of Cellulose Based on the Two-Domain Structure of Cellobiohydrolase I
journal, March 1991

  • Ståhlberg, Jerry; Johansson, Gunnar; Pettersson, Göran
  • Nature Biotechnology, Vol. 9, Issue 3, p. 286-290
  • DOI: 10.1038/nbt0391-286

High Speed Atomic Force Microscopy Visualizes Processive Movement of Trichoderma reesei Cellobiohydrolase I on Crystalline Cellulose
journal, October 2009

  • Igarashi, Kiyohiko; Koivula, Anu; Wada, Masahisa
  • Journal of Biological Chemistry, Vol. 284, Issue 52
  • DOI: 10.1074/jbc.M109.034611

The Mechanism of Cellulose Hydrolysis by a Two-Step, Retaining Cellobiohydrolase Elucidated by Structural and Transition Path Sampling Studies
journal, December 2013

  • Knott, Brandon C.; Haddad Momeni, Majid; Crowley, Michael F.
  • Journal of the American Chemical Society, Vol. 136, Issue 1
  • DOI: 10.1021/ja410291u

Activity Studies and Crystal Structures of Catalytically Deficient Mutants of Cellobiohydrolase I fromTrichoderma reesei
journal, November 1996

  • Ståhlberg, Jerry; Divne, Christina; Koivula, Anu
  • Journal of Molecular Biology, Vol. 264, Issue 2
  • DOI: 10.1006/jmbi.1996.0644

Hypocrea jecorina (Trichoderma reesei) Cel7A as a molecular machine: A docking study
journal, July 2005

  • Mulakala, Chandrika; Reilly, Peter J.
  • Proteins: Structure, Function, and Bioinformatics, Vol. 60, Issue 4
  • DOI: 10.1002/prot.20547

CASTp: computed atlas of surface topography of proteins with structural and topographical mapping of functionally annotated residues
journal, July 2006

  • Dundas, J.; Ouyang, Z.; Tseng, J.
  • Nucleic Acids Research, Vol. 34, Issue Web Server
  • DOI: 10.1093/nar/gkl282

Recalcitrant polysaccharide degradation by novel oxidative biocatalysts
journal, August 2013

  • Dimarogona, Maria; Topakas, Evangelos; Christakopoulos, Paul
  • Applied Microbiology and Biotechnology, Vol. 97, Issue 19
  • DOI: 10.1007/s00253-013-5197-y

The three-dimensional crystal structure of the catalytic core of cellobiohydrolase I from Trichoderma reesei
journal, July 1994


Transient Kinetics and Rate-Limiting Steps for the Processive Cellobiohydrolase Cel7A: Effects of Substrate Structure and Carbohydrate Binding Domain
journal, November 2013

  • Cruys-Bagger, Nicolaj; Tatsumi, Hirosuke; Ren, Guilin Robin
  • Biochemistry, Vol. 52, Issue 49
  • DOI: 10.1021/bi401210n

Sequencing, biochemical characterization, crystal structure and molecular dynamics of cellobiohydrolase Cel7A from Geotrichum candidum 3C
journal, October 2015

  • Borisova, Anna S.; Eneyskaya, Elena V.; Bobrov, Kirill S.
  • FEBS Journal, Vol. 282, Issue 23
  • DOI: 10.1111/febs.13509

C1-Cx revisited: intramolecular synergism in a cellulase.
journal, November 1994

  • Din, N.; Damude, H. G.; Gilkes, N. R.
  • Proceedings of the National Academy of Sciences, Vol. 91, Issue 24
  • DOI: 10.1073/pnas.91.24.11383

Computational Investigation of the pH Dependence of Loop Flexibility and Catalytic Function in Glycoside Hydrolases
journal, March 2013

  • Bu, Lintao; Crowley, Michael F.; Himmel, Michael E.
  • Journal of Biological Chemistry, Vol. 288, Issue 17
  • DOI: 10.1074/jbc.M113.462465

Cellobiohydrolase Hydrolyzes Crystalline Cellulose on Hydrophobic Faces
journal, January 2011

  • Liu, Yu-San; Baker, John O.; Zeng, Yining
  • Journal of Biological Chemistry, Vol. 286, Issue 13
  • DOI: 10.1074/jbc.M110.216556

Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms
journal, May 2014

  • Bodenheimer, Annette M.; Cuneo, Matthew J.; Swartz, Paul D.
  • Acta Crystallographica Section F Structural Biology Communications, Vol. 70, Issue 6
  • DOI: 10.1107/S2053230X14008851

Structural Changes of the Active Site Tunnel of Humicola insolens Cellobiohydrolase, Cel6A, upon Oligosaccharide Binding ,
journal, July 1999

  • Varrot, Annabelle; Schülein, Martin; Davies, Gideon J.
  • Biochemistry, Vol. 38, Issue 28
  • DOI: 10.1021/bi9903998

Engineering the Exo-loop of Trichoderma reesei Cellobiohydrolase, Cel7A. A comparison with Phanerochaete chrysosporium Cel7D
journal, October 2003

  • von Ossowski, Ingemar; Ståhlberg, Jerry; Koivula, Anu
  • Journal of Molecular Biology, Vol. 333, Issue 4, p. 817-829
  • DOI: 10.1016/S0022-2836(03)00881-7

Veratryl Alcohol Oxidase Activity of a Chemically Modified Cellulase Protein
journal, August 1994

  • Evans, B. R.; Margalit, R.; Woodward, J.
  • Archives of Biochemistry and Biophysics, Vol. 312, Issue 2
  • DOI: 10.1006/abbi.1994.1332

Enzymatic hydrolysis of cellulosic biomass
journal, July 2011


Computational Evaluation of the Dynamic Fluctuations of Peripheral Loops Enclosing the Catalytic Tunnel of a Family 7 Cellobiohydrolase
journal, April 2014

  • Granum, David M.; Schutt, Timothy C.; Maupin, C. Mark
  • The Journal of Physical Chemistry B, Vol. 118, Issue 20
  • DOI: 10.1021/jp5011555

Features and development of Coot
journal, March 2010

  • Emsley, P.; Lohkamp, B.; Scott, W. G.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4
  • DOI: 10.1107/S0907444910007493

Carbohydrate-binding modules: fine-tuning polysaccharide recognition
journal, September 2004

  • Boraston, Alisdair B.; Bolam, David N.; Gilbert, Harry J.
  • Biochemical Journal, Vol. 382, Issue 3
  • DOI: 10.1042/BJ20040892

Bio3d: an R package for the comparative analysis of protein structures
journal, August 2006


REFMAC 5 for the refinement of macromolecular crystal structures
journal, March 2011

  • Murshudov, Garib N.; Skubák, Pavol; Lebedev, Andrey A.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444911001314

Force calculations in automated docking: Enzyme-substrate interactions in Fusarium oxysporum Cel7B
journal, September 2005

  • Mulakala, Chandrika; Reilly, Peter J.
  • Proteins: Structure, Function, and Bioinformatics, Vol. 61, Issue 3
  • DOI: 10.1002/prot.20632

Structural basis for enantiomer binding and separation of a common β-blocker: crystal structure of cellobiohydrolase Cel7A with bound (S)-propranolol at 1.9 Å resolution
journal, January 2001

  • Ståhlberg, Jerry; Henriksson, Hongbin; Divne, Christina
  • Journal of Molecular Biology, Vol. 305, Issue 1
  • DOI: 10.1006/jmbi.2000.4237

Carbohydrate–Protein Interactions That Drive Processive Polysaccharide Translocation in Enzymes Revealed from a Computational Study of Cellobiohydrolase Processivity
journal, June 2014

  • Knott, Brandon C.; Crowley, Michael F.; Himmel, Michael E.
  • Journal of the American Chemical Society, Vol. 136, Issue 24
  • DOI: 10.1021/ja504074g

Towards a molecular-level theory of carbohydrate processivity in glycoside hydrolases
journal, June 2014


Flexibility analysis of enzyme active sites by crystallographic temperature factors
journal, February 2003

  • Yuan, Zheng; Zhao, Ju; Wang, Zhi-Xin
  • Protein Engineering, Design and Selection, Vol. 16, Issue 2
  • DOI: 10.1093/proeng/gzg014

Limited proteolysis of the cellobiohydrolase I from Trichoderma reesei: Separation of functional domains
journal, August 1986


Respective roles of short- and long-range interactions in protein folding.
journal, February 1978

  • Go, N.; Taketomi, H.
  • Proceedings of the National Academy of Sciences, Vol. 75, Issue 2
  • DOI: 10.1073/pnas.75.2.559

A Processive Single-Headed Motor: Kinesin Superfamily Protein KIF1A
journal, February 1999


Cellobiohydrolase 1 from Trichoderma reesei degrades cellulose in single cellobiose steps
journal, December 2015

  • Brady, Sonia K.; Sreelatha, Sarangapani; Feng, Yinnian
  • Nature Communications, Vol. 6, Issue 1
  • DOI: 10.1038/ncomms10149

Molecular Dynamics Simulations of Family 7 Cellobiohydrolase Mutants Aimed at Reducing Product Inhibition
journal, September 2014

  • Silveira, Rodrigo L.; Skaf, Munir S.
  • The Journal of Physical Chemistry B, Vol. 119, Issue 29
  • DOI: 10.1021/jp509911m

Loop Motions Important to Product Expulsion in the Thermobifida fusca Glycoside Hydrolase Family 6 Cellobiohydrolase from Structural and Computational Studies
journal, September 2013

  • Wu, Miao; Bu, Lintao; Vuong, Thu V.
  • Journal of Biological Chemistry, Vol. 288, Issue 46
  • DOI: 10.1074/jbc.M113.502765

Long range recognition and selection in IDPs: the interactions of the C-terminus of p53
journal, March 2016

  • Kannan, Srinivasaraghavan; Lane, David P.; Verma, Chandra S.
  • Scientific Reports, Vol. 6, Issue 1
  • DOI: 10.1038/srep23750

Cellulose Degradation by Polysaccharide Monooxygenases
journal, June 2015


Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

VMD: Visual molecular dynamics
journal, February 1996


Structural, Biochemical, and Computational Characterization of the Glycoside Hydrolase Family 7 Cellobiohydrolase of the Tree-killing Fungus Heterobasidion irregulare
journal, January 2013

  • Momeni, Majid Haddad; Payne, Christina M.; Hansson, Henrik
  • Journal of Biological Chemistry, Vol. 288, Issue 8
  • DOI: 10.1074/jbc.M112.440891

Mechanism of the single-headed processivity: Diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin
journal, January 2000

  • Okada, Y.; Hirokawa, N.
  • Proceedings of the National Academy of Sciences, Vol. 97, Issue 2
  • DOI: 10.1073/pnas.97.2.640