Extraction of 211At from nitric acid solutions into various organic solvents for use as an α-source for radiation chemistry studies
Abstract
The partitioning of 211At from an irradiated bismuth target using solvent extraction into several organic solvents is presented. Although astatine speciation is difficult to measure given its invariably low chemical concentration its extraction here is consistent with the existence of a cationic species in nitric acid that is not reduced upon contact with the organic phase. This is consistent with previous work that postulated the most probable species in acidic solution as AtO+. The technique presented here has a simple experimental set up and provides high specific activity astatine solutions compatible for use in α-radiolysis studies.
- Authors:
-
- Chalmers Univ. of Technology, Gothenburg (Sweden). Nuclear Chemistry and Industrial Materials Recycling
- Rigshospitalet, Copenhagen (Denmark). The PET Centre
- California State Univ., Long Beach, CA (United States). Dept. of Chemistry and Biochemistry
- Idaho National Lab. (INL), Idaho Falls, ID (United States). Aqueous Separations and Radiochemistry Dept.
- Publication Date:
- Research Org.:
- Idaho National Laboratory (INL), Idaho Falls, ID (United States)
- Sponsoring Org.:
- USDOE Office of Nuclear Energy (NE), Fuel Cycle Technologies (NE-5)
- OSTI Identifier:
- 1400268
- Report Number(s):
- INL/JOU-16-40093
Journal ID: ISSN 0236-5731; PII: 5364
- Grant/Contract Number:
- AC07-05ID14517
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Journal of Radioanalytical and Nuclear Chemistry
- Additional Journal Information:
- Journal Volume: 314; Journal Issue: 1; Journal ID: ISSN 0236-5731
- Publisher:
- Springer
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 07 ISOTOPE AND RADIATION SOURCES; 211At; radiation chemistry; solvent extraction; speciation
Citation Formats
Ekberg, Christian, Jensen, Holger, Mezyk, Stephen P., Mincher, Bruce J., and Skarnemark, Gunnar. Extraction of 211At from nitric acid solutions into various organic solvents for use as an α-source for radiation chemistry studies. United States: N. p., 2017.
Web. doi:10.1007/s10967-017-5364-1.
Ekberg, Christian, Jensen, Holger, Mezyk, Stephen P., Mincher, Bruce J., & Skarnemark, Gunnar. Extraction of 211At from nitric acid solutions into various organic solvents for use as an α-source for radiation chemistry studies. United States. https://doi.org/10.1007/s10967-017-5364-1
Ekberg, Christian, Jensen, Holger, Mezyk, Stephen P., Mincher, Bruce J., and Skarnemark, Gunnar. Fri .
"Extraction of 211At from nitric acid solutions into various organic solvents for use as an α-source for radiation chemistry studies". United States. https://doi.org/10.1007/s10967-017-5364-1. https://www.osti.gov/servlets/purl/1400268.
@article{osti_1400268,
title = {Extraction of 211At from nitric acid solutions into various organic solvents for use as an α-source for radiation chemistry studies},
author = {Ekberg, Christian and Jensen, Holger and Mezyk, Stephen P. and Mincher, Bruce J. and Skarnemark, Gunnar},
abstractNote = {The partitioning of 211At from an irradiated bismuth target using solvent extraction into several organic solvents is presented. Although astatine speciation is difficult to measure given its invariably low chemical concentration its extraction here is consistent with the existence of a cationic species in nitric acid that is not reduced upon contact with the organic phase. This is consistent with previous work that postulated the most probable species in acidic solution as AtO+. The technique presented here has a simple experimental set up and provides high specific activity astatine solutions compatible for use in α-radiolysis studies.},
doi = {10.1007/s10967-017-5364-1},
journal = {Journal of Radioanalytical and Nuclear Chemistry},
number = 1,
volume = 314,
place = {United States},
year = {Fri Jul 21 00:00:00 EDT 2017},
month = {Fri Jul 21 00:00:00 EDT 2017}
}
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Works referenced in this record:
Wet harvesting of no-carrier-added 211At from an irradiated 209Bi target for radiopharmaceutical applications
journal, January 2004
- Yordanov, A. T.; Pozzi, O.; Carlin, S.
- Journal of Radioanalytical and Nuclear Chemistry, Vol. 262, Issue 3
SOLVENT EXTRACTION STUDIES OF INTERHALOGEN COMPOUNDS OF ASTATINE 1
journal, February 1961
- Appelman, Evan H.
- The Journal of Physical Chemistry, Vol. 65, Issue 2
Reactivity and Selectivity of the Astatine Interhalogen Compounds AtCI and AtBr Towards Simple Aromatic Substrates
journal, January 1977
- Meyer, G. -J.; RÖSsler, K.; StÖCklin, G.
- Radiochimica Acta, Vol. 24, Issue 2-3
Evaluation of a Wet Chemistry Method for Isolation of Cyclotron Produced [211At]Astatine
journal, September 2013
- Balkin, Ethan; Hamlin, Donald; Gagnon, Katherine
- Applied Sciences, Vol. 3, Issue 3
Extraction of astatine isotopes for development of radiopharmaceuticals using a 211Rn–211At generator
journal, September 2014
- Maeda, E.; Yokoyama, A.; Taniguchi, T.
- Journal of Radioanalytical and Nuclear Chemistry, Vol. 303, Issue 2
Design and evaluation of an external high-current target for production of 211 At
journal, October 2012
- Gagnon, K.; Risler, R.; Pal, S.
- Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 55, Issue 12
Extraction of Nitric Acid into Alcohol: Kerosene Mixtures
journal, August 2010
- Geist, Andreas
- Solvent Extraction and Ion Exchange, Vol. 28, Issue 5
Rapid continuous separation procedures for zirconium, niobium, technetium, bromine and iodine from complex reaction product mixtures
journal, January 1981
- Brodén, K.; Skarnemark, G.; Björnstad, T.
- Journal of Inorganic and Nuclear Chemistry, Vol. 43, Issue 4
Some microdosmetric data on Astatine-211
journal, January 2003
- Ünak, Turan
- Applied Radiation and Isotopes, Vol. 58, Issue 1
Alpha and gamma radiolysis of nuclear solvent extraction ligands used for An(III) and Ln(III) separations
journal, August 2012
- Mezyk, Stephen P.; Mincher, Bruce J.; Ekberg, Christian
- Journal of Radioanalytical and Nuclear Chemistry, Vol. 296, Issue 2
Separation of astatine-211 from bismuth metal
journal, January 1973
- Neirinckx, R. D.; Smit, J. A.
- Analytica Chimica Acta, Vol. 63, Issue 1
Using 211At as internal alpha radiolysis source allowing for simple detection of radiolysis products
journal, April 2010
- Ekberg, C.; Aneheim, E.; Fermvik, A.
- Radiation Physics and Chemistry, Vol. 79, Issue 4
Astatine-211: Its possible applications in cancer therapy
journal, January 1986
- Brown, I.
- International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 37, Issue 8
Dry-distillation of astatine-211 from irradiated bismuth targets: a time-saving procedure with high recovery yields
journal, August 2001
- Lindegren, Sture; Bäck, Tom; Jensen, Holger J.
- Applied Radiation and Isotopes, Vol. 55, Issue 2
Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle
journal, May 2016
- Dekempeneer, Yana; Keyaerts, Marleen; Krasniqi, Ahmet
- Expert Opinion on Biological Therapy, Vol. 16, Issue 8
Astatine Standard Redox Potentials and Speciation in Acidic Medium
journal, January 2010
- Champion, J.; Alliot, C.; Renault, E.
- The Journal of Physical Chemistry A, Vol. 114, Issue 1
Detonability of the System Nitrobenzene, Nitric Acid, and Water.
journal, April 1965
- Mason, C. M.; Van Dolah, R. W.; Ribovich, John
- Journal of Chemical & Engineering Data, Vol. 10, Issue 2
Tumor Immunotargeting Using Innovative Radionuclides
journal, February 2015
- Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline
- International Journal of Molecular Sciences, Vol. 16, Issue 2
Nuclear Data Sheets for A = 211
journal, June 2013
- Singh, Balraj; Abriola, Daniel; Baglin, Coral
- Nuclear Data Sheets, Vol. 114, Issue 6-7
Extraction of astatine-211 in diisopropylether (DIPE)
journal, January 2009
- Alliot, Cyrille; Chérel, Michel; Barbet, Jacques
- Radiochimica Acta, Vol. 97, Issue 3
Astatine
journal, February 1968
- Nefedov, V. D.; Norseev, Yu V.; Toropova, M. A.
- Russian Chemical Reviews, Vol. 37, Issue 2
Review Article: The Effects of Radiation Chemistry on Solvent Extraction: 1. Conditions in Acidic Solution and a Review of TBP Radiolysis
journal, January 2009
- Mincher, Bruce J.; Modolo, Giuseppe; Mezyk, Stephen P.
- Solvent Extraction and Ion Exchange, Vol. 27, Issue 1
Astatine-211: Production and Availability
journal, July 2011
- R. Zalutsky, Michael; Pruszynski, Marek
- Current Radiopharmaceuticalse, Vol. 4, Issue 3
Investigation of Astatine(III) Hydrolyzed Species: Experiments and Relativistic Calculations
journal, February 2013
- Champion, Julie; Sabatié-Gogova, Andréa; Bassal, Fadel
- The Journal of Physical Chemistry A, Vol. 117, Issue 9
Inorganic Astatine Chemistry
journal, January 1989
- Visser, Gerard W. M.
- Radiochimica Acta, Vol. 47, Issue 2-3
Works referencing / citing this record:
Investigation of a tellurium-packed column for isolation of astatine-211 from irradiated bismuth targets and demonstration of a semi-automated system
journal, November 2019
- Li, Yawen; Hamlin, Donald K.; Chyan, Ming-Kuan
- Scientific Reports, Vol. 9, Issue 1
Towards elucidating the radiochemistry of astatine – Behavior in chloroform
journal, November 2019
- Aneheim, Emma; Palm, Stig; Jensen, Holger
- Scientific Reports, Vol. 9, Issue 1