Roles of Individual Domains and Conserved Motifs of the AAA+ Chaperone ClpB in Oligomerization, ATP Hydrolysis, and Chaperone Activity
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journal
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March 2003 |
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity
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journal
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January 2007 |
A tightly regulated molecular toggle controls AAA+ disaggregase
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journal
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November 2012 |
The Amino-terminal Domain of ClpB Supports Binding to Strongly Aggregated Proteins
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journal
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August 2005 |
In vivo aspects of protein folding and quality control
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journal
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June 2016 |
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
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journal
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June 2017 |
Structure and Activity of ClpB from Escherichia coli: ROLE OF THE AMINO- AND CARBOXYL-TERMINAL DOMAINS
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journal
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September 2000 |
Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine
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journal
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August 2012 |
Molecular chaperones: guardians of the proteome in normal and disease states
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journal
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January 2015 |
Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine
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journal
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August 2012 |
Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation
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journal
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August 2012 |
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity
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journal
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January 2007 |
A tightly regulated molecular toggle controls AAA+ disaggregase
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journal
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November 2012 |
Hsp70 proteins bind Hsp100 regulatory M domains to activate AAA+ disaggregase at aggregate surfaces
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journal
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November 2012 |
Aggregate reactivation mediated by the Hsp100 chaperones
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journal
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April 2012 |
AAA+ Proteases: ATP-Fueled Machines of Protein Destruction
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journal
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July 2011 |
Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor
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journal
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May 2013 |
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
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journal
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June 2017 |
In vivo aspects of protein folding and quality control
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journal
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June 2016 |
ClpS, a Substrate Modulator of the ClpAP Machine
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journal
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March 2002 |
Structure and mechanism of the hexameric MecA–ClpC molecular machine
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journal
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March 2011 |
Protein rescue from aggregates by powerful molecular chaperone machines
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journal
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September 2013 |
Crystal Structure of the E. coli Hsp100 ClpB N-Terminal Domain
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journal
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March 2003 |
ClpB N-terminal domain plays a regulatory role in protein disaggregation
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journal
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November 2015 |
Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation
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journal
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April 2011 |
Inorganic phosphate assay with malachite green: An improvement and evaluation
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journal
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December 1982 |
In Vivo Monitoring of the Prion Replication Cycle Reveals a Critical Role for Sis1 in Delivering Substrates to Hsp104
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journal
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November 2008 |
Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation
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journal
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April 2011 |
The Structure of ClpB
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journal
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October 2003 |
AAA+ Proteases: ATP-Fueled Machines of Protein Destruction
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journal
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July 2011 |
Hsp104, Hsp70, and Hsp40
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journal
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July 1998 |
Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor
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journal
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May 2013 |
Structural basis for the disaggregase activity and regulation of Hsp104
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journal
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November 2016 |
Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA + Chaperone, ClpA
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journal
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September 2002 |
The M-Domain Controls Hsp104 Protein Remodeling Activity in an Hsp70/Hsp40-Dependent Manner
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journal
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September 2010 |
The M-Domain Controls Hsp104 Protein Remodeling Activity in an Hsp70/Hsp40-Dependent Manner
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journal
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September 2010 |
Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation
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journal
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August 2016 |
Peptide and Protein Binding in the Axial Channel of Hsp104: INSIGHTS INTO THE MECHANISM OF PROTEIN UNFOLDING
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journal
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August 2008 |
Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation
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journal
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August 2016 |
Orientation of the amino-terminal domain of ClpB affects the disaggregation of the protein: Orientation of the N-terminal domain of ClpB
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journal
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March 2012 |
Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions
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journal
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October 2008 |
Saccharomyces cerevisiae Hsp104 Enhances the Chaperone Capacity of Human Cells and Inhibits Heat Stress-Induced Proapoptotic Signaling †
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journal
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June 2004 |
The Hsp104 N-Terminal Domain Enables Disaggregase Plasticity and Potentiation
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journal
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March 2015 |
Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding Events
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journal
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January 2014 |
Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions
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journal
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October 2008 |
Molecular Basis for the Unique Role of the AAA + Chaperone ClpV in Type VI Protein Secretion
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journal
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July 2011 |
Arginine phosphorylation marks proteins for degradation by a Clp protease
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journal
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October 2016 |
CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation
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journal
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April 2010 |
N-Terminal Domain of Yeast Hsp104 Chaperone Is Dispensable for Thermotolerance and Prion Propagation but Necessary for Curing Prions by Hsp104 Overexpression
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journal
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April 2006 |
Dominant Gain-of-Function Mutations in Hsp104p Reveal Crucial Roles for the Middle Region
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journal
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May 2004 |
Protein rescue from aggregates by powerful molecular chaperone machines
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journal
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September 2013 |
Cooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregation
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journal
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May 2015 |
The N-terminal domain of Escherichia coli ClpB enhances chaperone function
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journal
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July 2005 |
The N-terminal domain of Escherichia coli ClpB enhances chaperone function
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journal
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July 2005 |
Cooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregation
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journal
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May 2015 |
The N Terminus of ClpB from Thermus thermophilus Is Not Essential for the Chaperone Activity
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journal
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September 2002 |
The Truncated Form of the Bacterial Heat Shock Protein ClpB/HSP100 Contributes to Development of Thermotolerance in the Cyanobacterium Synechococcus sp. Strain PCC 7942
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journal
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December 2000 |
Evidence for an Unfolding/Threading Mechanism for Protein Disaggregation by Saccharomyces cerevisiae Hsp104
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journal
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May 2004 |
Interaction of the N-terminal domain of Escherichia coli heat-shock protein ClpB and protein aggregates during chaperone activity
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journal
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December 2004 |
ClpB N-terminal domain plays a regulatory role in protein disaggregation
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journal
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November 2015 |
Aggregate reactivation mediated by the Hsp100 chaperones
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journal
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April 2012 |
Saccharomyces cerevisiae Hsp104 Enhances the Chaperone Capacity of Human Cells and Inhibits Heat Stress-Induced Proapoptotic Signaling †
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journal
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June 2004 |
Structure and mechanism of the hexameric MecA–ClpC molecular machine
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journal
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March 2011 |
N-Terminal Domain of Yeast Hsp104 Chaperone Is Dispensable for Thermotolerance and Prion Propagation but Necessary for Curing Prions by Hsp104 Overexpression
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journal
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April 2006 |
Arginine phosphorylation marks proteins for degradation by a Clp protease
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journal
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October 2016 |
[20] Processing of X-ray diffraction data collected in oscillation mode
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book
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January 1997 |
Conserved Amino Acid Residues within the Amino-terminal Domain of ClpB are Essential for the Chaperone Activity
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journal
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August 2002 |
Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation
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journal
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April 2008 |
Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding Events
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journal
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January 2014 |
Site-directed mutagenesis of the dual translational initiation sites of the clpB gene of Escherichia coli and characterization of its gene products.
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journal
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September 1993 |