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Title: Review of the algal biology program within the National Alliance for Advanced Biofuels and Bioproducts

In 2010,when the National Alliance for Advanced Biofuels and Bioproducts (NAABB) consortium began, little was known about the molecular basis of algal biomass or oil production. Very few algal genome sequences were available and efforts to identify the best-producing wild species through bioprospecting approaches had largely stalled after the U.S. Department of Energy's Aquatic Species Program. This lack of knowledge included how reduced carbon was partitioned into storage products like triglycerides or starch and the role played by metabolite remodeling in the accumulation of energy-dense storage products. Furthermore, genetic transformation and metabolic engineering approaches to improve algal biomass and oil yields were in their infancy. Genome sequencing and transcriptional profiling were becoming less expensive, however; and the tools to annotate gene expression profiles under various growth and engineered conditions were just starting to be developed for algae. It was in this context that an integrated algal biology program was introduced in the NAABB to address the greatest constraints limiting algal biomass yield. Our review describes the NAABB algal biology program, including hypotheses, research objectives, and strategies to move algal biology research into the twenty-first century and to realize the greatest potential of algae biomass systems to produce biofuels.
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  1. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
  2. Los Alamos National Lab. (LANL), Los Alamos, NM (United States); New Mexico Consortium, Los Alamos, NM (United States)
  3. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  4. US Dept. of Agriculture (USDA)., St. Louis, MO (United States). Donald Danforth Plant Science Center
  5. Univ. of California, Los Angeles, CA (United States). Dept. of Chemistry and Biochemistry
  6. Univ. of Arizona, Tucson, AZ (United States)
  7. Matrix Genetics, LLC, Seattle, WA (United States)
  8. Univ. of Washington, Seattle, WA (United States)
  9. Texas A&M Univ., College Station, TX (United States)
  10. New Mexico State Univ., Las Cruces, NM (United States)
  11. Washington Univ., St. Louis, MO (United States)
  12. Donald Danforth Plant Science Center, St. Louis, MO (United States)
  13. Michigan State Univ., East Lansing, MI (United States)
  14. Brooklyn College of the Univ. of New York, Brooklyn, NY (United States)
  15. Cellana Inc., Kailua-Kona, HI (United States)
Publication Date:
Report Number(s):
LA-UR-14-28953; LA-UR-16-21596
Journal ID: ISSN 2211-9264
Grant/Contract Number:
EE0003046; AC52-06NA25396
Published Article
Journal Name:
Algal Research
Additional Journal Information:
Journal Volume: 22; Journal ID: ISSN 2211-9264
Research Org:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org:
USDOE Office of Energy Efficiency and Renewable Energy (EERE), Bioenergy Technologies Office (EE-3B)
Country of Publication:
United States
59 BASIC BIOLOGICAL SCIENCES; 09 BIOMASS FUELS; Biological Science; Energy Sciences
OSTI Identifier:
Alternate Identifier(s):
OSTI ID: 1329552; OSTI ID: 1338798